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Effects of St. John's Wort on the Effectiveness of Oral Contraceptives



Effects of St. John's Wort on the Effectiveness of Oral Contraceptives

For Condition: Contraception
Status: No longer recruiting
Sponsor(s): National Center for Complementary and Alternative Medicine (NCCAM) ,
Synopsis: The purpose of this study is to evaluate the effects of a common herbal remedy, St. John's Wort, on the effectiveness of birth control pills. St. John's Wort has recently been shown to increase metabolism of some drugs. If it could increase metabolism of oral contraceptives as well, it may increase the risk of contraceptive failure and unintended pregnancy. Study participants will be evaluated for risk of ovulation on oral contraceptives before and during simultaneous therapy with St. John's Wort.
Details:
Eligibility:
Study Type:
  Interventional, Treatment, Non-Randomized, Single Blind, Placebo Control, Single Group Assignment, Pharmacokinetics/Dynamics Study
Minimum Age/Maximum Age: 18 Years/40 Years
Genders: Female
Protocol Entry Criteria: Inclusion Criteria: - Women taking or willing to take low dose oral contraceptives for 5 months - No contraindications to hormonal contraception
Total Enrollment: 25

Location and Contact Information:

Columbia University Department of Obstetrics & Gynecology
New York City,  New York,  10032
United States
 


Additional Information:
Study ID Numbers:
  1 R21 AT00836-01; 
Study Start Date: January 2002
Record last reviewed: March 2004
Additional information available at: clinicaltrials.gov
Clinicaltrials.gov Reference link: NCT00026013

Other Contraception Studies:
1. Emergency Contraception (ECP): Reducing Unintended Pregnancies

2. Effects of St. John's Wort on the Effectiveness of Oral Contraceptives

3. Quick Start Approach to Birth Control Pills

4. The Direct Access Study: Access to Hormonal Birth Control Through Community Pharmacies

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Other Contraception Clinical Trials
Other New York Clinical Trials
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