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Effects of Exercise on patients with Hemiparetic Stroke Clinical Trials Information presented on Clinical Trials Search isn't intended to be a substitute for proven healthcare advice, trips or treatment using a real physician. We are not docs. Always confer with your mD on Effects of Exercise on patients with Hemiparetic Stroke conditions. Clinical Trials Search.org is a site dedicated to listing clinical research studies in human subjects. Effects of Exercise on patients with Hemiparetic Stroke Clinical research trials and Effects of Exercise on patients with Hemiparetic Stroke medical trials take place in hundreds of localities across the U.S.. A clinical trial or clinical study is a research project with human volunteer subjects. Clinical drug trials and pharmaceutical clinical trials usually measure the effectiveness of new drugs. The intention of the studies / projects is to resolve certain human health questions. Clinical trials are a popular means for physicians, government agencies, and private sector corporations to detect remedies for all forms of circumstances, like Effects of Exercise on patients with Hemiparetic Stroke. Effects of Exercise on patients with Hemiparetic Stroke Clinical Trials and other clinical trials allow for volunteers to undergo healthcare treatment options before they are available to the masses. Most times the participants receive treatment for free, and every now and again they are paid for their time. Occasionally there is a cost for a Effects of Exercise on patients with Hemiparetic Stroke clinical trial. Subjects typically recieve the finest healthcare available for their Effects of Exercise on patients with Hemiparetic Stroke condition. Hazards are a reality, nonetheless, and might include more or frequent mD trips, health risks (potentially life-endangering), and/or the treatment being ineffective. Trials are federally regulated with stern guidelines to protect clinical trials subjects.
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Home > "E" Clinical Trials Conditions > Effects of Exercise on patients with Hemiparetic Stroke  Effects of Exercise on patients with Hemiparetic Stroke
Effects of Exercise on patients with Hemiparetic Stroke
For Condition: Cardiovascular Disease,Hemiplegia,Stroke
Status: Recruiting
Sponsor(s): Department of Veterans Affairs Medical Research Service ,
Synopsis: This randomized trial investigates the hypothesis that regular aerobic exercise training using a task specific gait training modality will improve cardiovascular fitness, functional mobility, and reduce risk factors for recurrent cardiovascular events in chronic hemiparetic stroke patients, when compared to matched controls performing just stretching.
Details: The aims are to determine whether 6 months progressive graded treadmill training: 1) improves cardiovascular fitness levels and reduces the excessive energy demands of hemiparetic gait, as defined by oxygen consumption levels based on open circuit spirometry during peak and submaximal exercise ambulation tasks; 2) increases free living physical activity measured by portable kinematic recording devices and quantitative in vivo determination of energy expenditure using stable isotopes; and, 3) improves the cardiovascular-metabolic risk factor profile including measures of key endogenous fibrinolysis regulatory enzymes [plasma tissue plasminogen activator (t-PA) and its main circulating inhibitor (PAI-1)], fasting lipoprotein lipid profiles, blood pressure, and oral glucose tolerance and insulin responses. Measurements of body composition at baseline and after training will further determine the effects of aerobic exercise training on muscle mass and central obesity.
Eligibility:
Study Type: Interventional, Treatment, Randomized, Active Control, Parallel Assignment, Efficacy Study
Minimum Age/Maximum Age: 40 Years/80 Years
Genders: Both
Protocol Entry Criteria: Males or Females Ages 40 yrs to 80 yrs who are chronic hemiparetic stroke patients.
Total Enrollment:
Location and Contact Information:
VA Maryland Health Care System *Recruiting*
Baltimore, Maryland, 21201
United States
Recruiting Richard Macko 410-605-7063
Additional Information:
Study ID Numbers: CADE-RA;
Study Start Date: July 1997
Record last reviewed: June 2001
Additional information available at: clinicaltrials.gov
Clinicaltrials.gov Reference link: NCT00018421
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Effects of Exercise on patients with Hemiparetic Stroke
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