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Effects of exercise on markers of inflammation in skeletal muscle in elderly hip fracture patients



Effects of exercise on markers of inflammation in skeletal muscle in elderly hip fracture patients

For Condition: Hip Fractures,Muscular Atrophy
Status: Completed
Sponsor(s): National Center for Research Resources (NCRR) ,
Synopsis: Decreased skeletal muscle mass is a prevalent condition among the elderly, and an important cause of disability and functional decline. The declines in muscle mass associated with aging may be related to alterations in specific kinds of growth factors in the muscle. Elderly hip fracture patients often have significant decreases in muscle mass. The purpose of this study is to investigate whether an exercise program can induce changes in muscle growth factors that are associated with increases in muscle mass and strength in elderly hip fracture patients.
Details:
Eligibility:
Study Type:
  Interventional, Treatment, Randomized, Single Group Assignment
Minimum Age/Maximum Age: 65 Years/
Genders: Both
Protocol Entry Criteria: Inclusion Criteria: - Enrollment in HSC protocol #97-0695 "Rehabilitation Intensification Post Hip Fracture" - Community-dwelling - Hip fracture within 16 weeks of the screening assessment for protocol 97-0695 - Persistent mobility and/or ADL impairments, but independent in ambulation - Modified Physical Performance Test (PPT) score between 12 and 28
Total Enrollment: 

Location and Contact Information:

Washington University
St. Louis,  Missouri,  63110
United States
 


Additional Information:
Study ID Numbers:
  NCRR-M01RR00036-0764;  M01RR00036
Study Start Date: 
Record last reviewed: December 2003
Additional information available at: clinicaltrials.gov
Clinicaltrials.gov Reference link: NCT00006194

Other Muscular Atrophy Studies:
1. The HIP Impact Protection Program (HIP PRO)

2. Effects of exercise on markers of inflammation in skeletal muscle in elderly hip fracture patients

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Effects of exercise on markers of inflammation in skeletal muscle in elderly hip fracture patients

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