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Double-Blind Study of Timunox (Thymopentin) in Asymptomatic HIV-Infected Patients Receiving Either Mono (AZT or ddI) or Combination (AZT / ddI or AZT / ddC) Anti-Retroviral Therapy Clinical Trials Facts presented on Clinical Trials Search isn't designed to be a substitute for proven healthcare advice, calls or treatment using a real mD. We aren't mDs. Always confer with your physician on Double-Blind Study of Timunox (Thymopentin) in Asymptomatic HIV-Infected Patients Receiving Either Mono (AZT or ddI) or Combination (AZT / ddI or AZT / ddC) Anti-Retroviral Therapy conditions. Clinical Trials Search.org is a website dedicated to listing clinical research studies in human subjects. Double-Blind Study of Timunox (Thymopentin) in Asymptomatic HIV-Infected Patients Receiving Either Mono (AZT or ddI) or Combination (AZT / ddI or AZT / ddC) Anti-Retroviral Therapy Clinical research trials and Double-Blind Study of Timunox (Thymopentin) in Asymptomatic HIV-Infected Patients Receiving Either Mono (AZT or ddI) or Combination (AZT / ddI or AZT / ddC) Anti-Retroviral Therapy healthcare trials happen in a lot of of localities across the United States of America. A clinical trial or clinical study is a research project with human volunteer subjects. Clinical drug trials and pharmaceutical clinical trials generally measure the potency of new drugs. The aim of the studies / undertakings is to answer particular human medical questions. Clinical trials are a popular manner for doctors, government agencies, and private sector corporations to discover remedies for all kinds of circumstances, such as Double-Blind Study of Timunox (Thymopentin) in Asymptomatic HIV-Infected Patients Receiving Either Mono (AZT or ddI) or Combination (AZT / ddI or AZT / ddC) Anti-Retroviral Therapy. Double-Blind Study of Timunox (Thymopentin) in Asymptomatic HIV-Infected Patients Receiving Either Mono (AZT or ddI) or Combination (AZT / ddI or AZT / ddC) Anti-Retroviral Therapy Clinical Trials and other clinical trials allow volunteers to get healthcare treatment alternatives before they are available to the general public. Most times the participants receive treatment for without cost, and occasionally they are paid for their time. Sometimes there is a cost for a Double-Blind Study of Timunox (Thymopentin) in Asymptomatic HIV-Infected Patients Receiving Either Mono (AZT or ddI) or Combination (AZT / ddI or AZT / ddC) Anti-Retroviral Therapy clinical trial. Human subjects often receive the most effective healthcare possible for their Double-Blind Study of Timunox (Thymopentin) in Asymptomatic HIV-Infected Patients Receiving Either Mono (AZT or ddI) or Combination (AZT / ddI or AZT / ddC) Anti-Retroviral Therapy condition. Risks are a reality, nonetheless, and may include more or frequent dr. calls, healthcare hazards (perhaps life-threatening), and/or the treatment being ineffective. Trials are federally governed with rigorous guidelines to protect clinical trials subjects.

Home > "D" Clinical Trials Conditions > Double-Blind Study of Timunox (Thymopentin) in Asymptomatic HIV-Infected Patients Receiving Either Mono (AZT or ddI) or Combination (AZT / ddI or AZT / ddC) Anti-Retroviral Therapy

Double-Blind Study of Timunox (Thymopentin) in Asymptomatic HIV-Infected Patients Receiving Either Mono (AZT or ddI) or Combination (AZT / ddI or AZT / ddC) Anti-Retroviral Therapy



Double-Blind Study of Timunox (Thymopentin) in Asymptomatic HIV-Infected Patients Receiving Either Mono (AZT or ddI) or Combination (AZT / ddI or AZT / ddC) Anti-Retroviral Therapy

For Condition: HIV Infections
Status: Completed
Sponsor(s): Immunobiology Research Institute ,
Synopsis: To confirm results from a previous study in which the combination of thymopentin plus zidovudine ( AZT ), an antiretroviral agent, slowed disease progression in HIV-infected asymptomatic patients. To evaluate the efficacy and safety of thymopentin in HIV-infected asymptomatic patients receiving either monotherapy with AZT, didanosine ( ddI ), or stavudine ( d4T ), or combination antiretroviral therapy with AZT / ddI or AZT / zalcitabine ( ddC ).
Details:
Eligibility:
Study Type:
  Interventional, Treatment, Double-Blind, Safety Study
Minimum Age/Maximum Age: 18 Years/
Genders: Both
Protocol Entry Criteria: Inclusion Criteria Patients must have: - Asymptomatic HIV infection. - CD4 count 100-400 cells/mm3. - No HIV-associated neurologic abnormalities or constitutional symptoms. - No oral hairy leukoplakia. - At least 6 months of prior AZT. Exclusion Criteria Co-existing Condition: Patients with the following symptoms or conditions are excluded: - Abnormal chest x-ray, consistent with active opportunistic infection. - Hypersensitivity to thymopentin. - Significant chronic underlying medical illness. - Grade 2 or worse peripheral neuropathy. Concurrent Medication: Excluded: - HIV vaccines. - Investigational or non-FDA approved medication. - Immunomodulatory therapies. - Experimental therapies. - Any antiretroviral therapy other than AZT, ddI, ddC, d4T, or 3TC. Patients with the following prior conditions are excluded: - Herpes zoster (within the past year). - Recurrent (> one episode) oral candidiasis (confirmed). - Vulvovaginal candidiasis (persistent, frequent, or poorly responsive to therapy). - Bacillary angiomatosis. - Listeriosis. - Idiopathic thrombocytopenia purpura. Prior Medication: Excluded at any time prior to study entry: More than one dose of thymopentin. Excluded within 30 days prior to study entry: - HIV vaccines. - Investigational or non-FDA approved medication. - Immunomodulatory therapies. - Experimental therapies. - Any antiretroviral therapy other than AZT, ddI, ddC, d4T, or 3TC. Required: - Prior AZT (>= 300 mg/day) for at least 6 months; on current regimen (any combination of approved nucleoside analogues) for at least 4 weeks. Significant active alcohol or drug abuse.
Total Enrollment: 

Location and Contact Information:

Van Etten Hosp / Bronx Municipal Hosp Ctr
Bronx,  New York,  10461
United States
 

West Paces Clinical Research Inc
Atlanta,  Georgia,  30327
United States
 

Initiativa Comunitaria de Investigacion
San Juan,  ,  00902
Puerto Rico
 

CRI of New England
Brookline,  Massachusetts,  02445
United States
 

Dr Christopher McNulty
Dallas,  Texas,  75219
United States
 

Ctr for Special Immunology
Irvine,  California,  92718
United States
 

Cleveland Clinic
Cleveland,  Ohio,  44106
United States
 

Rush Presbyterian - Saint Luke's Med Ctr
Chicago,  Illinois,  60612
United States
 

Community Research Initiative
Coral Gables,  Florida,  33146
United States
 

New York Hosp - Cornell Med Ctr
New York City,  New York,  10021
United States
 

Associates Med and Mental Health
Tulsa,  Oklahoma,  741141325
United States
 

Houston Clinical Research Network
Houston,  Texas,  77006
United States
 

Dr Patrick Hennessey
New York City,  New York,  10016
United States
 

HIV Research Group
San Diego,  California,  92102
United States
 

Univ of Kansas School of Medicine
Wichita,  Kansas,  67214
United States
 

SUNY / Health Sciences Ctr at Stony Brook
Stony Brook,  New York,  117948153
United States
 

Ctr for Special Immunology
New York City,  New York,  10010
United States
 

Harbor - UCLA Med Ctr
Torrance,  California,  90502
United States
 

Dr Howard A Grossman
New York City,  New York,  10014
United States
 

Dr Joel Godbey
Portland,  Oregon,  97232
United States
 

Ctr for Special Immunology
Ft. Lauderdale,  Florida,  33316
United States
 

Infectious Diseases Research Clinic / Indiana Univ Hosp
Indianapolis,  Indiana,  46202
United States
 

Dr Larry Bruni
Washington D.C.,  District of Columbia,  20003
United States
 

Ctr for Special Immunology
Chicago,  Illinois,  60657
United States
 

Fisher Med Group
Phoenix,  Arizona,  85013
United States
 

Stratogen of South Florida
Miami,  Florida,  33140
United States
 

Saint Joseph's Hosp / Infectious Disease Rsch Institute
Tampa,  Florida,  33614
United States
 

Philadelphia FIGHT
Philadelphia,  Pennsylvania,  19107
United States
 

Stratogen of Ft Lauderdale
Ft. Lauderdale,  Florida,  33334
United States
 

Kaiser Permanente Med Ctr
San Francisco,  California,  94115
United States
 

Kansas City AIDS Research Consortium
Kansas City,  Missouri,  641082792
United States
 

Novum Inc
Kirkland,  Washington,  98034
United States
 

Northwestern Univ Med Ctr
Chicago,  Illinois,  60611
United States
 

Novum Inc
Pittsburgh,  Pennsylvania,  15206
United States
 

Infectious Disease Research Institute Inc
Tampa,  Florida,  33614
United States
 

Central Texas Med Foundation
Austin,  Texas,  78751
United States
 

Beer Med Group
Los Angeles,  California,  90036
United States
 

Conant Med Group
San Francisco,  California,  94115
United States
 

Novum Inc
Washington D.C.,  District of Columbia,  20037
United States
 

Graduate Hosp
Philadelphia,  Pennsylvania,  19146
United States
 

AIDS Community Research Consortium
Redwood City,  California,  94063
United States
 

Dr Gary Blick
Greenwich,  Connecticut,  06830
United States
 

Dr David DiPietro
New York City,  New York,  10001
United States
 

Univ of Puerto Rico Med Sciences Campus
Rio Piedras,  ,  00935
Puerto Rico
 

Hampton Roads Med Specialists
Hampton,  Virginia,  23666
United States
 

Gottlieb Med Group
Pasadena,  California,  90112
United States
 

Lovelace Scientific Resource
Albuquerque,  New Mexico,  87108
United States
 

Pacific Oaks Med Group
Sherman Oaks,  California,  91403
United States
 

Nelson-Tebedo Community Clinic
Dallas,  Texas,  75219
United States
 

Systemic Mycoses Pathogen Study Group / Wash Univ Sch of Med
St. Louis,  Missouri,  63108
United States
 


Additional Information:
Study ID Numbers:
  015H;  07.32.033-93
Study Start Date: 
Record last reviewed: March 1996
Additional information available at: clinicaltrials.gov
Clinicaltrials.gov Reference link: NCT00002109

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