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Directly Observed Therapy in HIV Infected Adolescent Focus Groups



Directly Observed Therapy in HIV Infected Adolescent Focus Groups

For Condition: HIV Infections
Status: Recruiting
Sponsor(s): National Institute of Allergy and Infectious Diseases (NIAID) , National Institute of Child Health and Human Development (NICHD)
Synopsis: The purpose of this study is to help researchers use information from HIV infected adolescents to design a directly observed therapy (DOT) program that will help adolescents take their anti-HIV medications correctly.
Details: The rate of HIV infection among adolescents is increasing at an alarming rate. Adherence to antiretroviral therapy has been a major challenge in achieving and maintaining adequate control of the disease in this population. DOT has been shown effective in individuals with tuberculosis (TB), but DOT in HIV infected populations has not been thoroughly examined. This study will collect information from HIV infected adolescents in order to establish a DOT program that will increase successful adherence to HIV treatment and will benefit the public by preventing development of viral resistance and reducing the risk of transmission. Adolescent participants in this study will be assigned to one of three 2-hour focus group sessions, each at a different site. The participants will complete a questionnaire and will give input about designing a DOT intervention model that will be accepted by adolescents. The model will then be used in a pilot study to determine the feasibility of implementing DOT programs in the community to help HIV infected adolescents.
Eligibility:
Study Type:
  Observational, Cross-Sectional, Defined Population, Prospective Study
Minimum Age/Maximum Age: 16 Years/21 Years
Genders: Both
Protocol Entry Criteria: Inclusion Criteria: - HIV infected due to high-risk behavior - Regular attendee of local adolescent HIV support group - Current use of antiretrovirals or history of antiretroviral therapy - Permission of parent or legal guardian if participant is less than the legal age of consent. Assent of the minor participant should be obtained where required. Exclusion Criteria: - Perinatal HIV infection - Visibly distraught or emotionally unstable - Pregnancy or breast-feeding
Total Enrollment: 30

Location and Contact Information:

Overall Study Official:
PatriciaFlynn,  Study Chair,  St. Jude Children's Research Hospital

Los Angeles County Medical Center/USC *Recruiting*
Los Angeles,  California,  90033
United States
Recruiting Eva  Operskalski 323-226-2226


Additional Information:
Study ID Numbers:
  PACTG P1036A; 
Study Start Date: 
Record last reviewed: May 2004
Additional information available at: clinicaltrials.gov
Clinicaltrials.gov Reference link: NCT00079729

Other Hiv Infections Studies:
1. A Phase I, Observer-Blind, Placebo-Controlled Study of the Chiron Vaccine HIV p24/MF59 Administered to Healthy HIV-Seronegative Adults

2. A Study of Three Anti-HIV Drug Combinations in Patients Who Have Taken Amprenavir

3. A Phase III, Randomized, Double-Blind, Multicentre Study to Evaluate the Safety and Efficacy of 1592U89 in Patients With AIDS Dementia Complex

4. Measuring HIV Quality of Care

5. Safety of and Immune Response to Polyvalent HIV-1 Vaccine in HIV Uninfected Adults

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Directly Observed Therapy in HIV Infected Adolescent Focus Groups

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