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Diagnosis and Treatment of Pheochromocytoma Clinical Trials Info presented on Clinical Trials Search isn't intended to be a substitute for certified medical advice, calls or professional assistance using a genuine dr.. We aren't physicians. Always confer with your dr. on Diagnosis and Treatment of Pheochromocytoma conditions. Clinical Trials Search.org is a website committed to listing clinical research studies in human subjects. Diagnosis and Treatment of Pheochromocytoma Clinical research trials and Diagnosis and Treatment of Pheochromocytoma medical trials happen in hundreds of localities throughout the U.S.A.. A clinical trial or clinical study is a research project with human volunteer subjects. Clinical drug trials and pharmaceutical clinical trials typically measure the effectualness of new does drugs. The intent of the studies / undertakings is to answer particular human health questions. Clinical trials are a popular manner for physicians, government agencies, and private sector corporations to find cures for all kinds of circumstances, like Diagnosis and Treatment of Pheochromocytoma. Diagnosis and Treatment of Pheochromocytoma Clinical Trials and other clinical trials permit volunteers to acquire healthcare treatment options before they are available to the general public. Some times the subjects acquire professional assistance for free, and sometimes they are paid for their time. Sometimes there is a cost for a Diagnosis and Treatment of Pheochromocytoma clinical trial. Participants frequently obtain the most expert healthcare available for their Diagnosis and Treatment of Pheochromocytoma condition. Dangers are a reality, nevertheless, and can include more or frequent doctor calls, health risks (potentially life-jeopardizing), and/or the treatment being ineffectual. Trials are federally regulated with strict guidelines to protect clinical trials subjects.
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Home > "D" Clinical Trials Conditions > Diagnosis and Treatment of Pheochromocytoma  Diagnosis and Treatment of Pheochromocytoma
Diagnosis and Treatment of Pheochromocytoma
For Condition: Pheochromocytoma
Status: Completed
Sponsor(s): National Heart, Lung, and Blood Institute (NHLBI) ,
Synopsis: Pheochromocytoma is a tumor of the adrenal gland. This tumor is typically benign (not cancerous) and can be cured by surgical removal. However, pheochromocytomas produce neurohormones called cateholamines (epinephrine and norepinephrine). High levels of catecholamines can result in high blood pressure, headaches, sweating, heart palpitations, nausea, vomiting, and other symptoms. These tumors are considered dangerous because of their unpredictable behavior. Patients with pheochromocytoma may experience blood pressures high enough to cause a stroke or heart attack in patients. This study is designed to take patients suspected of having pheochromocytoma and confirm the diagnosis. This will be done using a variety of laboratory tests including a clonidine suppression test and glucagon stimulation test. These tests use drugs that can stimulate or reduce the activity of the tumor if it is present in the body. Once a diagnosis is confirmed, patients participating in this study will undergo standard procedures to find the exact location of the tumor and receive standard therapy for the condition.
Details: Patients suspected of having a pheochromocytoma will be studied via a series of tests in an attempt to ascertain biochemically whether or not they really have such a tumor. These procedures will include a standard clonidine suppression test and a standard glucagon stimulation test. Once the diagnosis has been made on the basis of biochemistry, then localization and therapy will be done via standard procedures. Measurement of plasma metanephrines on mailed samples is available for physicians who seek further evidence for the diagnosis of pheochromocytoma.
Eligibility:
Study Type: Observational, Natural History
Minimum Age/Maximum Age: /
Genders: Both
Protocol Entry Criteria: Patients of any age and either sex who are suspected of having a pheochromocytoma on the basis of one or more of the following: 1. hypertensive episodes in a normotensive subject, 2. abnormal levels of blood and/or urinary catecholamines or their metabolites, or 3. an otherwise unexplained abdominal mass. Patients without any evidence of pheochromocytoma are excluded.
Total Enrollment: 240
Location and Contact Information:
National Heart, Lung and Blood Institute (NHLBI)
Bethesda, Maryland, 20892
United States
Additional Information:
Study ID Numbers: 880189; 88-H-0189
Study Start Date: October 14, 1988
Record last reviewed: November 17, 1999
Additional information available at: clinicaltrials.gov
Clinicaltrials.gov Reference link: NCT00001229
Other Pheochromocytoma Studies:
1. Catecholamine Release in Pseudopheochromocytoma
2. Blood Sampling for Neurochemical and Genetic Testing
3. Diagnosis and Treatment of Pheochromocytoma
4. Diagnosis of Pheochromocytoma
5. 131MIBG to Treat Malignant Pheochromocytoma
Related Studies:
Other Pheochromocytoma Clinical Trials
Other Maryland Clinical Trials
Other Bethesda Clinical Trials
Diagnosis and Treatment of Pheochromocytoma
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