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Home > "C" Clinical Trials Conditions > Comparison of daily nocturnal hemodialysis with daily hemodialysis  Comparison of daily nocturnal hemodialysis with daily hemodialysis
Comparison of daily nocturnal hemodialysis with daily hemodialysis
For Condition: Kidney Failure, Chronic
Status: Recruiting
Sponsor(s): National Center for Research Resources (NCRR) ,
Synopsis: Hemodialysis remains associated with a high mortality (approximately 22% per year) and many complications despite improvements over the last twenty years. Several nephrologists have suggested that increasing the frequency and amount of dialysis will result in improved outcomes. In fact, various forms of daily dialysis have been performed in over 300 patients in the last 30 years with improvements in blood pressure, quality-of-life, bone disease, and other complications of renal failure. Whether this form of treatment can be expanded to the 220,000 Americans on hemodialysis is unknown. The primary outcome of this study is to determine the effectiveness of nocturnal dialysis in hemodialysis patients in St. Louis. If the pilot study is effective, then participation in a larger, multicenter trial is expected. The endpoints measured are use of antihypertension medications, improvement in secondary hyperparathyroidism and use of phosphorus binders, quality-of-life measured by SF-36 surveys, and improvement in physical function as measured by maximal oxygen uptake.
Details:
Eligibility:
Study Type: Interventional, Treatment, Non-Randomized, Efficacy Study
Minimum Age/Maximum Age: 21 Years/75 Years
Genders: Both
Protocol Entry Criteria: Adult patients with chronic renal failure requiring intermittent hemodialysis with a life expectancy of greater than 2 years
Total Enrollment:
Location and Contact Information:
Washington University School of Medicine *Recruiting*
St. Louis, Missouri, 63108
United States
Recruiting Brent Miller 314-286-0801
Additional Information:
Study ID Numbers: NCRR-M01RR00036-0781;
Study Start Date:
Record last reviewed: December 2003
Additional information available at: clinicaltrials.gov
Clinicaltrials.gov Reference link: NCT00012441
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3. Study to Evaluate the Effects of Zemplar Injection and Calcijex on Intestinal Absorption of Calcium
4. Study to evaluate the effectiveness of StaphVAX in adults on hemodialysis
5. Fifteen Year Follow-up of 5,500 Black and 5,500 Other Hypertensives
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Comparison of daily nocturnal hemodialysis with daily hemodialysis
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