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Combination Chemotherapy in Treating Children With Progressive Brain Tumors Clinical Trials Data presented on Clinical Trials Search is not meant to be a substitute for qualified health advice, visits or treatment with a real mD. We are not doctors. Always consult your doctor about Combination Chemotherapy in Treating Children With Progressive Brain Tumors conditions. Clinical Trials Search.org is a site devoted to listing clinical research studies in human subjects. Combination Chemotherapy in Treating Children With Progressive Brain Tumors Clinical research trials and Combination Chemotherapy in Treating Children With Progressive Brain Tumors healthcare trials happen in many of places across the United States. A clinical trial or clinical study is a research project with human volunteer subjects. Clinical drug trials and pharmaceutical clinical trials generally assess the effectivity of new drugs. The purpose of the studies / projects is to solve particular human medical questions. Clinical trials are a popular way for doctors, government agencies, and private sector companies to discover cures for all varieties of conditions, such as Combination Chemotherapy in Treating Children With Progressive Brain Tumors. Combination Chemotherapy in Treating Children With Progressive Brain Tumors Clinical Trials and other clinical trials allow volunteers to have health treatment alternatives before they are available to the masses. Some times the human subjects obtain treatment for without cost, and sometimes they are compensated for their time. Occasionally there is a cost for a Combination Chemotherapy in Treating Children With Progressive Brain Tumors clinical trial. Test subjects oftentimes receive the most effective healthcare possible for their Combination Chemotherapy in Treating Children With Progressive Brain Tumors condition. Dangers are a reality, however, and may include extra or frequent physician visits, healthcare dangers (possibly life-jeopardising), and/or the treatment being uneffective. Trials are federally governed with rigorous guidelines to protect clinical trials patients.
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Home > "C" Clinical Trials Conditions > Combination Chemotherapy in Treating Children With Progressive Brain Tumors  Combination Chemotherapy in Treating Children With Progressive Brain Tumors
Combination Chemotherapy in Treating Children With Progressive Brain Tumors
For Condition: recurrent childhood brain stem glioma,recurrent childhood visual pathway glioma,recurrent childhood cerebral astrocytoma,recurrent childhood cerebellar astrocytoma
Status: Recruiting
Sponsor(s): Children's Oncology Group , National Cancer Institute (NCI)
Synopsis: RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Combining more than one drug may kill more tumor cells. PURPOSE: Randomizedphase III trial to determine the effectiveness of combination chemotherapy in treating children who have low-grade astrocytomas or other residual tumors of the brain.
Details: OBJECTIVES: - Compare the event free survival as a result of treatment with carboplatin and vincristine versus thioguanine, procarbazine, lomustine, and vincristine in children with progressive brain tumors. - Estimate tumor response rates to each regimen of chemotherapy in these patients. - Determine toxic effects and quality of life of children treated with each regimen of chemotherapy. - Investigate biological and clinical factors which may predict tumor response and early progression (tumor size, location, pathologic subtype, cytogenetics, and proliferative index by MIB-1 (Ki67)) in these patients. - Investigate factors contributing to neuropsychological and endocrine status of children with brain tumors treated without irradiation. OUTLINE: This is a randomized study. Patients are stratified according to site of disease, status at entry, and pathology. Patients are randomized to one of two treatment arms. Patients with neurofibromatosis are nonrandomly assigned to arm II. - Arm I: Patients receive induction with carboplatin and vincristine for 10 weeks followed by 2 weeks of rest. Induction is followed by 8 courses of maintenance beginning on day 84 of induction or upon hematopoietic recovery. Each course consists of 4 weekly doses of carboplatin and 3 weekly doses of vincristine (given concurrently with the first 3 weeks of carboplatin), followed by 2 weeks of rest. - Arm II: Patients receive oral thioguanine, procarbazine, and lomustine on days 0-4, followed by vincristine IV on days 14 and 28. Treatment continues every 6 weeks for a maximum of 8 courses. PROJECTED ACCRUAL: A total of 280-340 patients will be accrued over 4 years.
Eligibility:
Study Type: Interventional, Treatment
Minimum Age/Maximum Age: /9 Years
Genders: Both
Protocol Entry Criteria: DISEASE CHARACTERISTICS: - Pathologically confirmed low grade residual astrocytomas or other eligible residual tumors of the brain interpreted as low grade (WHO grades I and II) such as the following: - Glial Tumors - Astrocytic tumors - Low grade astrocytoma (variants: fibrillary, protoplasmic, gemistocytic) - Pilocytic astrocytoma - Pleomorphic xanthoastrocytomas - Subependymal giant cell astrocytoma - Infantile desmoplastic astrocytoma - Low grade oligodendroglial tumors - Low grade oligodendroglioma - Low grade mixed gliomas - Oligo-astrocytoma - Neuronal Tumors - Ganglioglioma (excluding tumors with anaplastic astrocytic components) - Infantile desmoplastic ganglioglioma - Chiasmatic-hypothalamic tumor without histologic confirmation - All of the following diagnostic tests (radiological or clinical evidence of progression, surgery, or confirmatory MRI) must be carried out within 6 weeks of enrollment into this study - Progressive disease following surgical excision based on clear radiological or clinical evidence of progression, or an incomplete excision (less than 95% or greater than 1.5 cm2) with necessity to begin treatment because of a risk of neurologic impairment with progression - Chiasmatic lesions that have contiguous extensions of tumor into other regions of the visual pathways demonstrated on contrast MRI will be eligible for study without histopathological confirmation - Patients with neurofibromatosis who have radiographic diagnosis of chiasmatic-hypothalamic tumor are eligible for the study, without requiring a biopsy confirmation of tumor histology, but not unless tumor progression is documented radiographically - No intrinsic brain stem tumors of the pons or isolated optic nerve tumors without definitive involvement of the optic chiasm PATIENT CHARACTERISTICS: Age: - Under 10 Performance status: - Not specified Life expectancy: - Not specified Hematopoietic: - Absolute neutrophil count greater than 1,000/mm^3 (arm II) - Platelet count greater than 100,000/mm^3 (arm II) Hepatic: - Not specified Renal: - Creatinine less than 1.5 times upper limit of normal for age OR - Creatinine clearance or radioisotope GFR greater than 70 mL/min or equivalent GFR as determined by the institutional normal range PRIOR CONCURRENT THERAPY: Biologic therapy: - Not specified Chemotherapy: - No prior chemotherapy for the tumor Endocrine therapy: - Prior corticosteroid therapy allowed Radiotherapy: - No prior radiotherapy for the tumor Surgery: - See Disease Characterisitcs Other: - Prior diuretic therapy allowed
Total Enrollment:
Location and Contact Information:
Overall Study Official:
JoannAter, Study Chair, M.D. Anderson Cancer Center
Cedars-Sinai Comprehensive Cancer Center at Cedars-Sinai Medical Center *Recruiting*
Los Angeles, California, 90048
United States
Recruiting Moshe Arditi 310-423-4471
Chao Family Comprehensive Cancer Center at University of California Irvine Cancer Center *Recruiting*
Orange, California, 92868
United States
Recruiting Stanley Calderwood 714-456-6615
Swiss Pediatric Oncology Group Lausanne *Recruiting*
Lausanne, , CH 1011
Switzerland
Recruiting Maja Popovic 41-21-314-3567
UNMC Eppley Cancer Center at the University of Nebraska Medical Center *Recruiting*
Omaha, Nebraska, 68198-2168
United States
Recruiting Peter Coccia 402-559-7257
William Beaumont Hospital - Royal Oak *Recruiting*
Royal Oak, Michigan, 48073-6769
United States
Recruiting Charles Main 248-551-0360
Marshfield Clinic *Recruiting*
Marshfield, Wisconsin, 54449-5772
United States
Recruiting H. Nickerson 715-387-5018
University of Minnesota Cancer Center *Recruiting*
Minneapolis, Minnesota, 55455
United States
Recruiting Joseph Neglia 612-625-6903
Children's Hospitals and Clinics - Minnesota *Recruiting*
St. Paul, Minnesota, 55102
United States
Recruiting Christopher Moertel 651-220-6732
State University of New York Health Science Center at Brooklyn College of Medicine *Recruiting*
Brooklyn, New York, 11203
United States
Recruiting Sreedhar Rao 718-270-1693
Children's Hospital of Austin *Recruiting*
Austin, Texas, 78701
United States
Recruiting Sharon Lockhart 512-324-8480
Curtis & Elizabeth Anderson Cancer Institute at Memorial Health University Medical Center *Recruiting*
Savannah, Georgia, 31405
United States
Recruiting Tribhawan Vats 912-350-8194
Children's Hospital of Western Ontario *Recruiting*
London, Ontario, N6C 2V5
Canada
Recruiting Anne Lois Cairney 519-685-8494
Saskatoon Cancer Centre *Recruiting*
Saskatoon, Saskatchewan, S7N 4H4
Canada
Recruiting Ali Kaiser 306-655-2684
Kosair Children's Hospital *Recruiting*
Louisville, Kentucky, 40202-3830
United States
Recruiting Salvatore Bertolone 502-852-8450
Herbert Irving Comprehensive Cancer Center at Columbia University *Recruiting*
New York City, New York, 10032
United States
Recruiting Linda Granowetter 212-305-8652
Children's Hospital of Pittsburgh *Recruiting*
Pittsburgh, Pennsylvania, 15213
United States
Recruiting Arthur Ritchey 412-692-5949
Children's Hospital and Research Center at Oakland *Recruiting*
Oakland, California, 94609-1809
United States
Recruiting James Feusner 510-428-3000
Phoenix Children's Hospital *Recruiting*
Phoenix, Arizona, 85016
United States
Recruiting Dale Singer 602-546-0920
Mission St. Joseph's Health System *Recruiting*
Asheville, North Carolina, 28801
United States
Recruiting Orren Beaty 823-213-5770
Baystate Medical Center *Recruiting*
Springfield, Massachusetts, 01107
United States
Recruiting David Steele 413-794-9338
Lutheran General Cancer Care Center *Recruiting*
Park Ridge, Illinois, 60068-1174
United States
Recruiting Jong-Hyo Kwon 847-723-5962
Memorial Sloan-Kettering Cancer Center *Recruiting*
New York City, New York, 10021
United States
Recruiting Peter Steinherz 212-639-7951
Brooklyn Hospital Center *Recruiting*
Brooklyn, New York, 11201-5493
United States
Recruiting Swayamprabha Sadanandan 718-250-6074
Sinai Hospital of Baltimore *Recruiting*
Baltimore, Maryland, 21225
United States
Recruiting Joseph Wiley 410-601-5864
Kaiser Permanente Medical Center - Santa Clara *Recruiting*
Santa Clara, California, 95051-5386
United States
Recruiting Carolyn Russo 408-236-5028
CCOP - Christiana Care Health Services *Recruiting*
Newark, Delaware, 19713
United States
Recruiting Gregory Griffin 302-651-5757
Methodist Cancer Center at Methodist Specialty and Transplant Hospital *Recruiting*
San Antonio, Texas, 78229-3902
United States
Recruiting Jaime Estrada 210-575-8130
City of Hope Comprehensive Cancer Center *Recruiting*
Duarte, California, 91010-3000
United States
Recruiting Judith Sato 626-930-5430
Markey Cancer Center at University of Kentucky Chandler Medical Center *Recruiting*
Lexington, Kentucky, 40536-0284
United States
Recruiting Martha Greenwood 859-323-6771
St. Mary's - Duluth Clinic Cancer Center *Recruiting*
Duluth, Minnesota, 55805
United States
Recruiting Jacquelyn Wiermaa 218-786-3625
West Virginia University Hospitals *Recruiting*
Morgantown, West Virginia, 26506-9300
United States
Recruiting Frank Keller 304-293-1217
Jonsson Comprehensive Cancer Center, UCLA *Recruiting*
Los Angeles, California, 90095-1781
United States
Recruiting Stephen Feig 310-825-5268
Albert Einstein Clinical Cancer Center *Recruiting*
Bronx, New York, 10461
United States
Recruiting Eva Radel 718-920-7844
Cincinnati Children's Hospital Medical Center *Recruiting*
Cincinnati, Ohio, 45229-3039
United States
Recruiting John Perentesis 513-636-6090
Starship Children's Hospital *Recruiting*
Auckland, ,
New Zealand
Recruiting Lochie Teague 64-9-307-4949 ext. 6295
Princess Margaret Hospital for Children *Recruiting*
Perth, Western Australia, 6001
Australia
Recruiting David Baker 61-8-9340-8234
St. Joseph's Hospital and Medical Center *Recruiting*
Paterson, New Jersey, 07503
United States
Recruiting Mary Bonilla 973-754-3230
MBCCOP - LSU Health Sciences Center *Recruiting*
New Orleans, Louisiana, 70112
United States
Recruiting Jill Gilbert 504-568-5136
Children's Hospital Medical Center of Akron *Recruiting*
Akron, Ohio, 44308
United States
Recruiting Jeffrey Hord 330-543-8580
New York Weill Cornell Cancer Center at Cornell University *Recruiting*
New York City, New York, 10021
United States
Recruiting Patricia Giardina 212-746-3400
Texas Tech University Health Sciences Center School of Medicine *Recruiting*
Amarillo, Texas, 79106
United States
Recruiting Curtis Turner 806-354-5434
Loma Linda University Cancer Institute at Loma Linda University Medical Center *Recruiting*
Loma Linda, California, 92354
United States
Recruiting Antranik Bedros 909-558-3391
Sioux Valley Hospital at University of South Dakota Medical Center *Recruiting*
Sioux Falls, South Dakota, 57117
United States
Recruiting Jakica Tancabelic 605-333-7171
Children's Hospital of Orange County *Recruiting*
Orange, California, 92868
United States
Recruiting Wei-Ping Shen 714-532-8636
Meritcare Roger Maris Cancer Center *Recruiting*
Fargo, North Dakota, 58122
United States
Recruiting Nathan Kobrinsky 701-234-2735
Santa Barbara Cottage Hospital *Recruiting*
Santa Barbara, California, 93102
United States
Recruiting Felicity Hodder 805-569-8394
Children's Hospital of Philadelphia *Recruiting*
Philadelphia, Pennsylvania, 19104
United States
Recruiting Beverly Lange 215-590-2249
Children's Hospital of the King's Daughters *Recruiting*
Norfolk, Virginia, 23507
United States
Recruiting Rebecca Byrd 757-668-7243
Josephine Ford Cancer Center at Henry Ford Hospital *Recruiting*
Detroit, Michigan, 48202
United States
Recruiting Hassan Yaish 313-916-3138
Mayo Clinic Cancer Center *Recruiting*
Rochester, Minnesota, 55905
United States
Recruiting Carola Arndt 507-284-4822
Children's Hospital of Omaha *Recruiting*
Omaha, Nebraska, 68114
United States
Recruiting Minnie Abromowitch 402-955-3950
Covenant Children's Hospital *Recruiting*
Lubbock, Texas, 79410
United States
Recruiting John Iacuone 806-725-1011
University of Chicago Cancer Research Center *Recruiting*
Chicago, Illinois, 60601
United States
Recruiting James Nachman 773-702-6808
St. Vincent Mercy Medical Center *Recruiting*
Toledo, Ohio, 43608
United States
Recruiting Rama Jasty 419-251-8215
Medical College of Georgia Comprehensive Cancer Center *Recruiting*
Augusta, Georgia, 30912-4000
United States
Recruiting Hernan Sabio 706-721-3626
CCOP - Columbia River Oncology Program *Recruiting*
Portland, Oregon, 97225
United States
Recruiting Keith Lanier 503-216-6260
Toledo Children's Hospital *Recruiting*
Toledo, Ohio, 43601
United States
Recruiting Richard Shore 419-471-5437
Dakota Cancer Institute at Innovis Health - Dakota Clinic *Recruiting*
Fargo, North Dakota, 58103-4940
United States
Recruiting Janet Tillisch 701-364-4966
Southern California Permanente Medical Group *Recruiting*
Downey, California, 90242
United States
Recruiting Willye Powell 562-803-2472
IWK Health Centre *Recruiting*
Halifax, Nova Scotia, B3J 3G9
Canada
Recruiting Dorothy Barnard 902-470-8291
Children's Mercy Hospital *Recruiting*
Kansas City, Missouri, 64108
United States
Recruiting Maxine Hetherington 816-234-3265
Indiana University Cancer Center *Recruiting*
Indianapolis, Indiana, 46202-5289
United States
Recruiting Robert Fallon 317-274-8784
Newark Beth Israel Medical Center *Recruiting*
Newark, New Jersey, 07112-2094
United States
Recruiting Peri Kamalakar 973-926-7161
Blumenthal Cancer Center at Carolinas Medical Center *Recruiting*
Charlotte, North Carolina, 28232-2861
United States
Recruiting Daniel McMahon 704-355-1130
East Tennessee Children's Hospital *Recruiting*
Knoxville, Tennessee, 37901
United States
Recruiting Ray Pais 865-541-8266
Cabell Huntington Hospital *Recruiting*
Huntington, West Virginia, 25701
United States
Recruiting Andrew Pendleton 304-691-1384
Presbyterian-St Luke's Medical Center *Recruiting*
Denver, Colorado, 80218
United States
Recruiting Stephen Palmer 719-471-2462
University of Connecticut Cancer Center at University of Connecticut Health Center *Recruiting*
Farmington, Connecticut, 06360-7106
United States
Recruiting Arnold Altman 860-545-9630
Spectrum Health and DeVos Children's Hospital *Recruiting*
Grand Rapids, Michigan, 49503
United States
Recruiting David Freyer 616-391-2086
Bronson Methodist Hospital *Recruiting*
Kalamazoo, Michigan, 49007
United States
Recruiting Leonard Mattano 269-341-6350
Mary Bridge Children's Health Center *Recruiting*
Tacoma, Washington, 98415-0299
United States
Recruiting William Thomas 253-403-4915
Children's Hospital Central California *Recruiting*
Madera, California, 93638-8762
United States
Recruiting Vonda Crouse 559-353-5480
CCOP - Beaumont *Recruiting*
Royal Oak, Michigan, 48073-6769
United States
Recruiting David Decker 248-551-7695
Lineberger Comprehensive Cancer Center at University of North Carolina - Chapel Hill *Recruiting*
Chapel Hill, North Carolina, 27599-7295
United States
Recruiting Stuart Gold 919-966-0985
Children's National Medical Center *Recruiting*
Washington D.C., District of Columbia, 20010-2970
United States
Recruiting Nita Seibel 202-884-2144
Mountain States Tumor Institute - Boise *Recruiting*
Boise, Idaho, 83712
United States
Recruiting J. Johnston 208-381-2782
Children's Medical Center - Dayton *Recruiting*
Dayton, Ohio, 45404
United States
Recruiting Emmett Broxson 937-641-3111
Kaiser Permanente Medical Center - San Francisco Geary Campus *Recruiting*
San Francisco, California, 94115
United States
Recruiting Kenneth Leung 415-833-3528
Schneider Children's Hospital *Recruiting*
New Hyde Park, New York, 11042
United States
Recruiting Arlene Redner 718-470-3460
Rhode Island Hospital *Recruiting*
Providence, Rhode Island, 02818
United States
Recruiting William Ferguson 401-444-5171
Medical City Dallas Hospital *Recruiting*
Dallas, Texas, 75230
United States
Recruiting Carl Lenarsky 214-788-6647
UCSF Comprehensive Cancer Center *Recruiting*
San Francisco, California, 94115
United States
Recruiting Katherine Matthay 415-353-9510
Geisinger Medical Center *Recruiting*
Danville, Pennsylvania, 17822-1320
United States
Recruiting Jeffrey Taylor 570-271-6848
University of Michigan Comprehensive Cancer Center *Recruiting*
Ann Arbor, Michigan, 48109-0914
United States
Recruiting Raymond Hutchinson 734-936-8785
Brookdale University Hospital and Medical Center *Recruiting*
Brooklyn, New York, 11212
United States
Recruiting Kusum Viswanathan 718-240-5904
CancerCare Manitoba *Recruiting*
Winnipeg, Manitoba, R3E 0V9
Canada
Recruiting Rochelle Yanofsky 204-787-4163
University of Illinois Medical Center *Recruiting*
Chicago, Illinois, 60612
United States
Recruiting Mary Schmidt 312-996-6143
Penn State Cancer Institute at Milton S. Hershey Medical Center *Recruiting*
Hershey, Pennsylvania, 17033-0850
United States
Recruiting John Neely 717-531-6012
CCOP - Marshfield Clinic Research Foundation *Recruiting*
Marshfield, Wisconsin, 54449
United States
Recruiting Tarit Banerjee 715-387-5134
Kaiser Permanente Medical Center/Kaiser Foundation Hospital - San Diego *Recruiting*
San Diego, California, 92120
United States
Recruiting Wellington Loh 619-516-6144
AFLAC Cancer Center and Blood Disorders Service of Children's Healthcare of Atlanta - Scottish Rite Campus *Recruiting*
Atlanta, Georgia, 30342
United States
Recruiting Stephen Lauer 404-250-2781
University of Wisconsin Comprehensive Cancer Center *Recruiting*
Madison, Wisconsin, 53792-6164
United States
Recruiting Diane Puccetti 608-263-0320
Swiss Pediatric Oncology Group Geneva *Recruiting*
Geneva, , CH 1211
Switzerland
Recruiting Pierre Wacker 41-22-382-3311
Children's Hospitals and Clinics - Minneapolis *Recruiting*
Minneapolis, Minnesota, 55404
United States
Recruiting Maura O'Leary 612-813-5940
Children's Hospital Los Angeles *Recruiting*
Los Angeles, California, 90027-0700
United States
Recruiting Paul Gaynon 323-669-2163
Sunrise Hospital and Medical Center *Recruiting*
Las Vegas, Nevada, 89109
United States
Recruiting Jonathan Bernstein 702-732-0971
University of Texas - MD Anderson Cancer Center *Recruiting*
Houston, Texas, 77030-4009
United States
Recruiting Joann Ater 713-792-6665
Doernbecher Children's Hospital at Oregon Health & Science University *Recruiting*
Portland, Oregon, 97239-3098
United States
Recruiting H. Nicholson 503-494-1543
New York Medical College *Recruiting*
Valhalla, New York, 10595
United States
Recruiting M. Ozkaynak 914-493-7997
Southern Illinois University School of Medicine *Recruiting*
Springfield, Illinois, 62794-9658
United States
Recruiting Gregory Brandt 217-545-5817
Long Island Cancer Center at Stony Brook University Hospital *Recruiting*
Stony Brook, New York, 11794
United States
Recruiting Robert Parker 631-689-6000
Ireland Cancer Center *Recruiting*
Cleveland, Ohio, 44106-5065
United States
Recruiting Eric Kodish 216-844-5432
Children's Hospital and Regional Medical Center - Seattle *Recruiting*
Seattle, Washington, 98105
United States
Recruiting Douglas Hawkins 206-987-3096
Janeway Children's Health and Rehabilitation Centre *Recruiting*
St. John's, Newfoundland and Labrador, A1B 3V6
Canada
Recruiting John Hand 709-777-4799
Valerie Fund Children's Center at Atlantic Health *Recruiting*
Summit, New Jersey, 07901
United States
Recruiting Hazem Mahmoud 973-971-6731
Holden Comprehensive Cancer Center at University of Iowa *Recruiting*
Iowa City, Iowa, 52242-1009
United States
Recruiting Raymond Tannous 319-356-1905
Cancer Center of Albany Medical Center *Recruiting*
Albany, New York, 12208
United States
Recruiting Jennifer Pearce 518-262-5513
David Grant Medical Center *Recruiting*
Travis Air Force Base, California, 94535
United States
Recruiting Peter Chenaille 707-423-7176
East Tennessee State University Cancer Center at Johnson City Medical Center *Recruiting*
Johnson City, Tennessee, 37604
United States
Recruiting Sharon Castellino 423-433-6200
Allan Blair Cancer Centre *Recruiting*
Regina, Saskatchewan, S4T 7T1
Canada
Recruiting Christina Suan Goh 306-766-2205
Deaconess Medical Center *Recruiting*
Spokane, Washington, 99210-0248
United States
Recruiting Steven Bergstrom 509-473-7012
University Hospital at State University of New York - Upstate Medical University *Recruiting*
Syracuse, New York, 13210
United States
Recruiting Ronald Dubowy 315-464-5294
Children's Hospital of Columbus *Recruiting*
Columbus, Ohio, 43205-2696
United States
Recruiting Amanda Termuhlen 614-722-3552
Maimonides Medical Center *Recruiting*
Brooklyn, New York, 11219
United States
Recruiting Ludovico Guarini 718-283-8173
British Columbia Children's Hospital *Recruiting*
Vancouver, British Columbia, V6H 3V4
Canada
Recruiting Paul Rogers 604-875-2322
Sydney Children's Hospital *Recruiting*
Randwick, New South Wales, 2031
Australia
Recruiting Glenn Marshall 61-2-9382-1721
Bellin Memorial Hospital *Recruiting*
Green Bay, Wisconsin, 54301
United States
Recruiting Dorothy Ganick 920-433-6025
Raymond Blank Memorial Hospital for Children *Recruiting*
Des Moines, Iowa, 50308
United States
Recruiting Torrey Mitchell 515-241-8912
Medical Center of Central Georgia *Recruiting*
Macon, Georgia, 31201
United States
Recruiting Hassan Dannawi 478-633-1104
Children's Hospital of Denver *Recruiting*
Denver, Colorado, 80218-1088
United States
Recruiting Roger Giller 303-861-6892
CCOP - Scott and White Hospital *Recruiting*
Temple, Texas, 76508
United States
Recruiting Lucas Wong 254-724-7048
Gundersen Lutheran Cancer Center at Gundersen Lutheran Medical Center *Recruiting*
La Crosse, Wisconsin, 54601
United States
Recruiting Robert Ettinger 608-782-7300
North Shore University Hospital *Recruiting*
Manhasset, New York, 11030
United States
Recruiting Indira Sahdev 718-470-3460
Cancer Institute of New Jersey *Recruiting*
New Brunswick, New Jersey, 08903
United States
Recruiting Richard Drachtman 732-235-7898
Broward General Medical Center *Recruiting*
Ft. Lauderdale, Florida, 33316
United States
Recruiting Rudolph Roskos 954-355-4527
Breslin Cancer Center at Ingham Regional Medical Center *Recruiting*
Lansing, Michigan, 48910
United States
Recruiting Renuka Gera 517-334-2337
Vanderbilt-Ingram Cancer Center at Vanderbilt Medical Center *Recruiting*
Nashville, Tennessee, 37232-6838
United States
Recruiting James Whitlock 615-936-1762
Lombardi Cancer Center at Georgetown University Medical Center *Recruiting*
Washington D.C., District of Columbia, 20007
United States
Recruiting Aziza Shad 202-687-2224
St. Barnabas Medical Center *Recruiting*
Livingston, New Jersey, 07039
United States
Recruiting Brenda Sison 973-322-2800
Swiss Pediatric Oncology Group Bern *Recruiting*
Bern, , CH 3010
Switzerland
Recruiting Annette Ridolfi-Luethy 41-31-632-9372
Group Health Central Hospital *Recruiting*
Seattle, Washington, 98112
United States
Recruiting Philip Herzog 425-883-5291
Additional Information:
Study ID Numbers: CDR0000065394; COG-A9952,CCG-A9952,POG-A9952,CCG-9952
Study Start Date:
Record last reviewed: September 2000
Additional information available at: clinicaltrials.gov
Clinicaltrials.gov Reference link: NCT00002944
Other Recurrent Childhood Brain Stem Glioma Studies:
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2. Vinorelbine in Treating Children With Recurrent or Refractory Cancers
3. Combination Chemotherapy in Treating Children With Progressive Brain Tumors
4. Docetaxel in Treating Children With Recurrent Solid Tumors
5. O6-benzylguanine and Carmustine in Treating Children With Refractory CNS Tumors
Related Studies:
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Combination Chemotherapy in Treating Children With Progressive Brain Tumors
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