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Combination Chemotherapy in Treating Children With Newly Diagnosed Acute Lymphoblastic Leukemia Clinical Trials Facts presented on Clinical Trials Search isn't designed to be a substitute for proven healthcare advice, calls or treatment using a real mD. We aren't mDs. Always confer with your physician on Combination Chemotherapy in Treating Children With Newly Diagnosed Acute Lymphoblastic Leukemia conditions. Clinical Trials Search.org is a website dedicated to listing clinical research studies in human subjects. Combination Chemotherapy in Treating Children With Newly Diagnosed Acute Lymphoblastic Leukemia Clinical research trials and Combination Chemotherapy in Treating Children With Newly Diagnosed Acute Lymphoblastic Leukemia healthcare trials happen in a lot of of localities across the United States of America. A clinical trial or clinical study is a research project with human volunteer subjects. Clinical drug trials and pharmaceutical clinical trials generally measure the potency of new drugs. The aim of the studies / undertakings is to answer particular human medical questions. Clinical trials are a popular manner for doctors, government agencies, and private sector corporations to discover remedies for all kinds of circumstances, such as Combination Chemotherapy in Treating Children With Newly Diagnosed Acute Lymphoblastic Leukemia. Combination Chemotherapy in Treating Children With Newly Diagnosed Acute Lymphoblastic Leukemia Clinical Trials and other clinical trials allow volunteers to get healthcare treatment alternatives before they are available to the general public. Most times the participants receive treatment for without cost, and occasionally they are paid for their time. Sometimes there is a cost for a Combination Chemotherapy in Treating Children With Newly Diagnosed Acute Lymphoblastic Leukemia clinical trial. Human subjects often receive the most effective healthcare possible for their Combination Chemotherapy in Treating Children With Newly Diagnosed Acute Lymphoblastic Leukemia condition. Risks are a reality, nonetheless, and may include more or frequent dr. calls, healthcare hazards (perhaps life-threatening), and/or the treatment being ineffective. Trials are federally governed with rigorous guidelines to protect clinical trials subjects.
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Home > "C" Clinical Trials Conditions > Combination Chemotherapy in Treating Children With Newly Diagnosed Acute Lymphoblastic Leukemia  Combination Chemotherapy in Treating Children With Newly Diagnosed Acute Lymphoblastic Leukemia
Combination Chemotherapy in Treating Children With Newly Diagnosed Acute Lymphoblastic Leukemia
For Condition: untreated childhood acute lymphoblastic leukemia
Status: Recruiting
Sponsor(s): Children's Oncology Group , National Cancer Institute (NCI)
Synopsis: RATIONALE: Drugs used in chemotherapy use different ways to stop cancer cells from dividing so they stop growing or die. Combining more than one drug may kill more cancer cells. It is not yet known which regimen of chemotherapy is more effective for acute lymphoblastic leukemia. PURPOSE: Randomizedphase III trial to compare the effectiveness of four regimens of combination chemotherapy in treating children who have newly diagnosed acute lymphoblastic leukemia.
Details: OBJECTIVES: - Determine if multidrug delayed-intensification therapy improves outcome in children with newly diagnosed standard-risk acute lymphocytic leukemia. - Compare the efficacy and toxicity of methotrexate administered over 4 hours vs methotrexate administered over 24 hours in this patient population. - Determine the correlation between event-free survival, minimal residual disease, and early response in this patient population treated with this multiple drug regimen. OUTLINE: This is a randomized, multicenter study. - Induction (weeks 1-4): Patients receive induction therapy on POG 9900. - Patients are randomized to one of four treatment arms. Patients with t(1;19) are randomized to either arm III or arm IV. - Arm I (weeks 5-24): Patients receive IT methotrexate (MTX) on day 1 followed by MTX IV over 20 minutes followed by MTX continuously over 23.6 hours on weeks 7, 10, 13, 16,19, and 22. At 42 hours after the beginning of the MTX infusion, patients receive oral leucovorin calcium every 6 hours for a total of 3 doses. Patients also receive oral mercaptopurine daily beginning on week 5 and continuing until the completion of consolidation therapy; oral dexamethasone twice daily on days 1-7 of weeks 8 and 17; and vincristine IV on day 1 of weeks 8, 9, 17, and 18. - Arm II (weeks 5-24): Patients receive MTX IV over 4 hours on weeks 7, 10, 13, 16, 19, and 22. At 42 hours after the beginning of the MTX infusion, patients receive oral leucovorin calcium as in arm I. Patients also receive mercaptopurine, dexamethasone, vincristine, and IT MTX as in arm I. - Arm III (weeks 5-32): Patients receive MTX IV as in arm I on weeks 7, 10, 13, 24, 27, and 30; leucovorin calcium as in arm I; pegaspargase IM on day 2, 3, OR 4 of week 16; and oral mercaptopurine daily on weeks 5-13, and from week 24 until the completion of consolidation therapy. Patients also receive IT MTX as in arm I on weeks 7, 10, 13, 16, 20, 21, and 30; oral dexamethasone twice daily on weeks 8, 16-18, and 28 for a total of 35 days; vincristine IV on day 1 of weeks 8, 9, 16, 17, 18, 28, and 29; daunorubicin IV on day 1 of weeks 16-18; cyclophosphamide IV over 30 minutes on day 1 of week 20; cytarabine IV or subcutaneously daily on days 2-5 of weeks 20 and 21; and oral thioguanine daily on weeks 20-21. - Arm IV (weeks 5-32): Patients receive MTX IV as in arm II on weeks 7, 10, 13, 24, 27, and 30; leucovorin calcium as in arm I; and pegaspargase, mercaptopurine, IT MTX, dexamethasone, vincristine, daunorubicin, cyclophosphamide, cytarabine, and thioguanine as in arm III. - Intensive continuation (weeks 25-80): At weeks 25-72 for arms I and II, and at weeks 33-80 for arms III and IV, patients receive oral MTX every 6 hours for 4 doses on weeks 1, 3, 5, 7, 9, and 11; oral mercaptopurine daily; oral leucovorin calcium every 12 hours for 2 doses beginning 48 hours after the start of MTX; IT MTX and vincristine IV on day 1 of week 12; and oral dexamethasone twice daily on days 1-7, beginning with the administration of vincristine. Treatment repeats every 12 weeks for 4 courses. - Additional continuation (weeks 73-130): At weeks 73-130 for arms I and II, and at weeks 81-130 for arms III and IV, patients receive oral MTX weekly; oral mercaptopurine daily; vincristine IV on day 1 every 12 weeks; oral dexamethasone as during intensive continuation therapy; and IT MTX on day 1 every 12 weeks, beginning with the last week of the first course (in place of oral MTX). Patients are followed monthly for 1 year, every 2 months for 1 year, every 3 months for 1 year, every 6 months for 1 year, and then every 6-12 months for 1 year. PROJECTED ACCRUAL: A total of 1,014 patients will be accrued for this study within 3.22 years.
Eligibility:
Study Type: Interventional, Treatment
Minimum Age/Maximum Age: 1 Year/21 Years
Genders: Both
Protocol Entry Criteria: DISEASE CHARACTERISTICS: - Confirmed diagnosis of newly diagnosed B-precursor acute lymphocytic leukemia - Standard risk (not low, high, or very high risk) - Prior registration and treatment on POG 9900 Classification Study PATIENT CHARACTERISTICS: Age: - 1 to 21 at diagnosis Performance status: - Not specified Life expectancy: - Not specified Hematopoietic: - Not specified Hepatic: - Not specified Renal: - Not specified Other: - Not pregnant or nursing - Fertile patients must use effective contraception PRIOR CONCURRENT THERAPY: Biologic therapy - Not specified Chemotherapy - Not specified Endocrine therapy - Not specified Radiotherapy - Not specified Surgery - Not specified
Total Enrollment:
Location and Contact Information:
Overall Study Official:
NaomiWinick, Study Chair, Simmons Cancer Center
Children's Hospital of Greenville Hospital System *Recruiting*
Greenville, South Carolina, 29605
United States
Recruiting Cary Stroud 864-455-8898
CCOP - Marshfield Clinic Research Foundation *Recruiting*
Marshfield, Wisconsin, 54449
United States
Recruiting Tarit Banerjee 715-387-5134
University of South Alabama Medical Center *Recruiting*
Mobile, Alabama, 36604
United States
Recruiting Yih-Ming Yang 251-405-5115
Advocate Hope Children's Hospital *Recruiting*
Oak Lawn, Illinois, 60453
United States
Recruiting Sharad Salvi 708-346-4094
Norris Cotton Cancer Center at Dartmouth Medical School *Recruiting*
Lebanon, New Hampshire, 03756
United States
Recruiting Eric Larsen 603-650-5541
Yale Comprehensive Cancer Center *Recruiting*
New Haven, Connecticut, 06520-8028
United States
Recruiting Jack Hoff 203-785-4095
All Children's Hospital *Recruiting*
St. Petersburg, Florida, 33701
United States
Recruiting Jerry Barbosa 727-892-4176
University of Missouri - Columbia *Recruiting*
Columbia, Missouri, 65203
United States
Recruiting Katherine Kelly 573-882-3933
Naval Medical Center, Portsmouth *Recruiting*
Portsmouth, Virginia, 23708-5100
United States
Recruiting Paulette Bryant 804-398-5767
Nemours Children's Clinic *Recruiting*
Jacksonville, Florida, 32207
United States
Recruiting Eric Sandler 904-390-3793
San Antonio Military Pediatric Cancer and Blood Disorders Center *Recruiting*
Lackland Air Force Base, Texas, 78236
United States
Recruiting Aaron Pitney 210-292-5684
Driscoll Children's Hospital *Recruiting*
Corpus Christi, Texas, 78466
United States
Recruiting Judith Mullins 361-694-5311
St. Jude Children's Research Hospital *Recruiting*
Memphis, Tennessee, 38105-2794
United States
Recruiting Ching-Hon Pui 901-495-3335
Tripler Army Medical Center *Recruiting*
Honolulu, Hawaii, 96859-5000
United States
Recruiting Braden Shoupe 808-433-6057
Vermont Cancer Center at University of Vermont *Recruiting*
Burlington, Vermont, 05401-3498
United States
Recruiting Alan Homans 802-847-2850
Joe DiMaggio Children's Hospital at Memorial *Recruiting*
Hollywood, Florida, 33021
United States
Recruiting Iftikhar Hanif 954-986-2234
St. John Hospital and Medical Center *Recruiting*
Detroit, Michigan, 48236
United States
Recruiting Hadi Sawaf 313-343-3964
Kansas Cancer Institute at the University of Kansas Medical Center *Recruiting*
Kansas City, Kansas, 66160-7357
United States
Recruiting Robert Trueworthy 913-588-6340
Mount Sinai School of Medicine *Recruiting*
New York City, New York, 10029
United States
Recruiting Elizabeth Raetz 212-241-7022
Kaiser Permanente Medical Center - Santa Clara *Recruiting*
Santa Clara, California, 95051-5386
United States
Recruiting Carolyn Russo 408-236-5028
Tampa Children's Hospital *Recruiting*
Tampa, Florida, 33677-4227
United States
Recruiting Cameron Tebbi 813-870-4252
Simmons Cancer Center at University of Texas Southwestern Medical Center - Dallas *Recruiting*
Dallas, Texas, 75390-9063
United States
Recruiting Naomi Winick 214-648-3074
Arizona Cancer Center at University of Arizona Health Sciences Center *Recruiting*
Tucson, Arizona, 85724
United States
Recruiting Michael Graham 520-626-6044
Madigan Army Medical Center *Recruiting*
Tacoma, Washington, 98431-5000
United States
Recruiting Kelly Faucette 253-968-1864
San Jorge Childrens Hospital *Recruiting*
Santurce, , 00912
Puerto Rico
Recruiting Luis Clavell 787-728-1575
Cancer Center at Hackensack University Medical Center *Recruiting*
Hackensack, New Jersey, 07601
United States
Recruiting Michael Harris 201-996-5437
Midwest Children's Cancer Center *Recruiting*
Milwaukee, Wisconsin, 53226
United States
Recruiting Bruce Camitta 414-456-4118
Children's Memorial Hospital - Chicago *Recruiting*
Chicago, Illinois, 60614
United States
Recruiting Susan Cohn 773-880-4562
Massey Cancer Center at Virginia Commonwealth University *Recruiting*
Richmond, Virginia, 23298-0037
United States
Recruiting Edward Russell 804-828-0450
James P. Wilmot Cancer Center at University of Rochester Medical Center *Recruiting*
Rochester, New York, 14642
United States
Recruiting Barbara Asselin 716-275-2981
University of Texas Medical Branch *Recruiting*
Galveston, Texas, 77555-0361
United States
Recruiting Kwesi Sackey 409-772-2341
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins *Recruiting*
Baltimore, Maryland, 21231-2410
United States
Recruiting Cindy Schwartz 410-955-2457
Saint Jude Midwest Affiliate *Recruiting*
Peoria, Illinois, 61637
United States
Recruiting John McCallister 309-624-4945
Warren Clinic *Recruiting*
Tulsa, Oklahoma, 74136
United States
Recruiting Martina Hum 918-494-2525 ext. 2557
Shands Cancer Center at the University of Florida Health Science Center *Recruiting*
Gainesville, Florida, 32610-0296
United States
Recruiting Stephen Hunger 352-392-5633
Tulane University School of Medicine *Recruiting*
New Orleans, Louisiana, 70112
United States
Recruiting Marshall Schorin 504-588-5412
Cross Cancer Institute *Recruiting*
Edmonton, Alberta, T6G 1Z2
Canada
Recruiting Paul Grundy 780-432-8894
Keesler Medical Center - Keesler Air Force Base *Recruiting*
Keesler AFB, Mississippi, 39534-2511
United States
Recruiting Wanda Salzer 228-377-6524
Oklahoma University Medical Center at University of Oklahoma Health Sciences Center *Recruiting*
Oklahoma City, Oklahoma, 73126
United States
Recruiting William Meyer 405-271-4022
Swiss Pediatric Oncology Group Bern *Recruiting*
Bern, , CH 3010
Switzerland
Recruiting Annette Ridolfi-Luethy 41-31-632-9372
University of California Davis Cancer Center *Recruiting*
Sacramento, California, 95817
United States
Recruiting Theodore Zwerdling 916-734-2781
CCOP - Wichita *Recruiting*
Wichita, Kansas, 67214-3882
United States
Recruiting David Rosen 316-268-5784
Stanford Cancer Center at Stanford University Medical Center *Recruiting*
Stanford, California, 94305-5208
United States
Recruiting Michael Link 650-723-5535
Hopital Sainte Justine *Recruiting*
Montreal, Quebec, H3T 1C5
Canada
Recruiting Albert Moghrabi 514-345-4969
Ochsner Clinic Foundation *Recruiting*
New Orleans, Louisiana, 70121
United States
Recruiting Marquis Hodes 504-842-5230
Baptist Hospital of Miami *Recruiting*
Miami, Florida, 33176-2197
United States
Recruiting Doured Daghistani 786-596-1960
CCOP - Columbia River Oncology Program *Recruiting*
Portland, Oregon, 97225
United States
Recruiting Keith Lanier 503-216-6260
Carilion Medical Center for Children *Recruiting*
Roanoke, Virginia, 24029
United States
Recruiting Joan Fisher 540-985-8055
Children's Hospital of Southwest Florida *Recruiting*
Ft. Myers, Florida, 33908
United States
Recruiting Emad Salman 941-432-3333
Rhode Island Hospital *Recruiting*
Providence, Rhode Island, 02818
United States
Recruiting William Ferguson 401-444-5171
Walter Reed Army Medical Center *Recruiting*
Washington D.C., District of Columbia, 20307-5000
United States
Recruiting E. Edwards 202-782-9449
Children's Hospital and Health Center, San Diego *Recruiting*
San Diego, California, 92123-4282
United States
Recruiting Richard Kadota 858-966-5811
Roswell Park Cancer Institute *Recruiting*
Buffalo, New York, 14263-0001
United States
Recruiting Martin Brecher 716-845-2333
Dana-Farber/Harvard Cancer Center at Dana Farber Cancer Institute *Recruiting*
Boston, Massachusetts, 02115
United States
Recruiting Holcombe Grier 617-632-3971
Via Christi Regional Medical Center *Recruiting*
Wichita, Kansas, 67214
United States
Recruiting David Rosen 316-268-5000
Wesley Medical Center *Recruiting*
Wichita, Kansas, 67214
United States
Recruiting David Rosen 316-962-2025
Marlene and Stewart Greenebaum Cancer Center, University of Maryland *Recruiting*
Baltimore, Maryland, 21201-1595
United States
Recruiting Neil Grossman 410-328-2808
Schneider Children's Hospital *Recruiting*
New Hyde Park, New York, 11042
United States
Recruiting Arlene Redner 718-470-3460
Mission St. Joseph's Health System *Recruiting*
Asheville, North Carolina, 28801
United States
Recruiting Orren Beaty 823-213-5770
University of Arkansas for Medical Sciences *Recruiting*
Little Rock, Arkansas, 72205
United States
Recruiting David Becton 501-320-5650
Cardinal Glennon Children's Hospital *Recruiting*
St. Louis, Missouri, 63104
United States
Recruiting Dennis O'Connor 314-577-5638
Leo W. Jenkins Cancer Center of University Health Systems of Eastern Carolina *Recruiting*
Greenville, North Carolina, 27858-4354
United States
Recruiting Sarah Strandjord 252-744-4676
Broward General Medical Center *Recruiting*
Ft. Lauderdale, Florida, 33316
United States
Recruiting Rudolph Roskos 954-355-4527
Rush-Presbyterian-St. Luke's Medical Center *Recruiting*
Chicago, Illinois, 60612
United States
Recruiting Allen Korenblit 312-942-5983
St. Mary's Hospital *Recruiting*
West Palm Beach, Florida, 33407
United States
Recruiting Narayana Gowda 561-840-6125
Kaiser Permanente Medical Center/Kaiser Foundation Hospital - San Diego *Recruiting*
San Diego, California, 92120
United States
Recruiting Wellington Loh 619-516-6144
MBCCOP - LSU Health Sciences Center *Recruiting*
New Orleans, Louisiana, 70112
United States
Recruiting Jill Gilbert 504-568-5136
University Hospital at State University of New York - Upstate Medical University *Recruiting*
Syracuse, New York, 13210
United States
Recruiting Ronald Dubowy 315-464-5294
AFLAC Cancer Center and Blood Disorders Service of Children's Healthcare of Atlanta - Scottish Rite Campus *Recruiting*
Atlanta, Georgia, 30342
United States
Recruiting Stephen Lauer 404-250-2781
Maine Children's Cancer Program *Recruiting*
Scarborough, Maine, 04074-9308
United States
Recruiting Craig Hurwitz 207-885-7565
Inova Fairfax Hospital *Recruiting*
Falls Church, Virginia, 22042-3300
United States
Recruiting Jay Greenberg 703-698-1110
Royal Children's Hospital *Recruiting*
Brisbane, Queensland, 4029
Australia
Recruiting Helen Irving 61-7-3636-8111
Long Island Cancer Center at Stony Brook University Hospital *Recruiting*
Stony Brook, New York, 11794
United States
Recruiting Robert Parker 631-689-6000
Duke Comprehensive Cancer Center *Recruiting*
Durham, North Carolina, 27710
United States
Recruiting Philip Breitfeld 919-684-3377
University of New Mexico Cancer Research and Treatment Center *Recruiting*
Albuquerque, New Mexico, 87131
United States
Recruiting Jami Frost 505-272-4461
Rebecca and John Moores UCSD Cancer Center *Recruiting*
La Jolla, California, 92093-0658
United States
Recruiting Richard Kadota 858-657-7020
Royal Children's Hospital *Recruiting*
Parkville, Victoria, 3052
Australia
Recruiting David Ashley 61-39-345-5522
Alberta Children's Hospital *Recruiting*
Calgary, Alberta, T2T 5C7
Canada
Recruiting Douglas Strother 403-943-7272
Florida Hospital Cancer Institute *Recruiting*
Orlando, Florida, 32804
United States
Recruiting Jane Crofton 407-303-2090
Cancer Research Center of Hawaii *Recruiting*
Honolulu, Hawaii, 96813
United States
Recruiting Robert Wilkinson 808-586-2979
McGill University Health Center - Montreal Children's Hospital *Recruiting*
Montreal, Quebec, H3G 1A4
Canada
Recruiting Carolyn Freeman 514-412-8040
Hollings Cancer Center at Medical University of South Carolina *Recruiting*
Charleston, South Carolina, 29425-0721
United States
Recruiting Julio Barredo 803-792-2957
Cook Children's Medical Center - Fort Worth *Recruiting*
Ft. Worth, Texas, 76104
United States
Recruiting Timothy Griffin 682-885-4020
Blumenthal Cancer Center at Carolinas Medical Center *Recruiting*
Charlotte, North Carolina, 28232-2861
United States
Recruiting Daniel McMahon 704-355-1130
Eastern Maine Medical Center *Recruiting*
Bangor, Maine, 04401
United States
Recruiting Judith Allen 207-973-7520
University of Alabama at Birmingham Comprehensive Cancer Center *Recruiting*
Birmingham, Alabama, 35233
United States
Recruiting Robert Castleberry 205-939-9285
Comprehensive Cancer Center at Wake Forest University *Recruiting*
Winston Salem, North Carolina, 27157-1081
United States
Recruiting Thomas McLean 336-716-4324
Cancer Center at the University of Virginia *Recruiting*
Charlottesville, Virginia, 22908
United States
Recruiting Pedro de Alarcon 434-924-5105
West Virginia University Hospitals *Recruiting*
Morgantown, West Virginia, 26506-9300
United States
Recruiting Frank Keller 304-293-1217
Miami Children's Hospital *Recruiting*
Miami, Florida, 33155-4069
United States
Recruiting Enrique Escalon 305-662-8360
Children's Hospital of Michigan *Recruiting*
Detroit, Michigan, 48201
United States
Recruiting Yaddanapudi Ravindranath 313-745-5649
CCOP - Scott and White Hospital *Recruiting*
Temple, Texas, 76508
United States
Recruiting Lucas Wong 254-724-7048
Children's Hospital at Westmead *Recruiting*
Westmead, New South Wales, 2145
Australia
Recruiting Geoffrey McCowage 61-2-9845-2122
Texas Children's Cancer Center *Recruiting*
Houston, Texas, 77030-2399
United States
Recruiting C. Steuber 832-822-4200
West Virginia University - Robert C. Byrd Health Sciences Center - Charleston Division *Recruiting*
Charleston, West Virginia, 25302
United States
Recruiting Sanjeev Grover 304-388-1540
Washington University Medical Center *Recruiting*
St. Louis, Missouri, 63105
United States
Recruiting Lori Luchtman-Jones 314-454-6018
Hospital for Sick Children *Recruiting*
Toronto, Ontario, M5G 1X8
Canada
Recruiting Victor Blanchette 416-598-5852
Nemours Children's Clinic-Orlando *Recruiting*
Orlando, Florida, 32806
United States
Recruiting Vincent Giusti 407-650-7230
Beth Israel Medical Center - Singer Division *Recruiting*
New York City, New York, 10128
United States
Recruiting Jeffrey Allen 212-870-9407
University of Miami Sylvester Cancer Center *Recruiting*
Miami, Florida, 33136
United States
Recruiting Stuart Toledano 305-585-5635
Medical City Dallas Hospital *Recruiting*
Dallas, Texas, 75230
United States
Recruiting Carl Lenarsky 214-788-6647
Swiss Pediatric Oncology Group Geneva *Recruiting*
Geneva, , CH 1211
Switzerland
Recruiting Pierre Wacker 41-22-382-3311
St. Vincent Hospital *Recruiting*
Green Bay, Wisconsin, 54307-9070
United States
Recruiting Jon Brandt 920-433-8670
Center for Cancer Prevention and Care at Scott and White Clinic *Recruiting*
Temple, Texas, 76508
United States
Recruiting Lawrence Frankel 254-724-2006
East Tennessee State University Cancer Center at Johnson City Medical Center *Recruiting*
Johnson City, Tennessee, 37604
United States
Recruiting Sharon Castellino 423-433-6200
Centre de Recherche du Centre Hospitalier de l'Universite Laval *Recruiting*
Sainte-Foy, Quebec, GIV 4G2
Canada
Recruiting Yvan Samson 418-656-4141
St. Christopher's Hospital for Children *Recruiting*
Philadelphia, Pennsylvania, 19134-1095
United States
Recruiting Gregory Halligan 215-427-5000
McMaster Children's Hospital at Hamilton Health Sciences *Recruiting*
Hamilton, Ontario, L8N 3Z5
Canada
Recruiting Ronald Barr 905-521-2100 ext. 73464
Floating Hospital for Children *Recruiting*
Boston, Massachusetts, 02111
United States
Recruiting Cynthia Kretschmar 617-636-5535
Legacy Emanuel Hospital and Health Center & Children's Hospital *Recruiting*
Portland, Oregon, 97227
United States
Recruiting Janice Olson 503-413-2200
University of Massachusetts Memorial Medical Center - University Campus *Recruiting*
Worcester, Massachusetts, 01655
United States
Recruiting Ghazala Usmani 508-856-4225
Sutter Cancer Center *Recruiting*
Sacramento, California, 95816
United States
Recruiting Yisheng Lee 916-454-6700
Massachusetts General Hospital Cancer Center *Recruiting*
Boston, Massachusetts, 02114
United States
Recruiting Howard Weinstein 617-724-3315
Children's Hospital of New Orleans *Recruiting*
New Orleans, Louisiana, 70118
United States
Recruiting Rajasekharan Warrier 504-568-4561
Hurley Medical Center *Recruiting*
Flint, Michigan, 48503
United States
Recruiting Susumu Inoue 810-762-7303
University of Mississippi Medical Center *Recruiting*
Jackson, Mississippi, 39216-4505
United States
Recruiting Dale Pullen 601-984-5220
Children's Hospital of Eastern Ontario *Recruiting*
Ottawa, Ontario, K1H 8L1
Canada
Recruiting Jacqueline Halton 613-737-7600 ext. 2370
Academisch Ziekenhuis Groningen *Recruiting*
Groningen, , 9700 RB
Netherlands
Recruiting Willem Kamps 31-50-361-4213
Presbyterian Healthcare *Recruiting*
Charlotte, North Carolina, 28233
United States
Recruiting Mark Mogul 704-384-1900
Sacred Heart Children's Hospital *Recruiting*
Pensacola, Florida, 32504
United States
Recruiting John Kelleher 850-505-4798
University of Texas Health Science Center at San Antonio *Recruiting*
San Antonio, Texas, 78207
United States
Recruiting Paul Thomas 210-704-3405
Additional Information:
Study ID Numbers: CDR0000067704; COG-P9905,POG-9905
Study Start Date:
Record last reviewed: October 2003
Additional information available at: clinicaltrials.gov
Clinicaltrials.gov Reference link: NCT00005596
Other Untreated Childhood Acute Lymphoblastic Leukemia Studies:
1. Combination Chemotherapy With or Without Donor Bone Marrow Transplantation in Treating Infants With Previously Untreated Acute Lymphoblastic Leukemia
2. Comparison of Different Combination Chemotherapy Regimens in Treating Children With Acute Lymphoblastic Leukemia
3. Combination Chemotherapy in Treating Patients With Newly Diagnosed Acute Lymphoblastic Leukemia
4. Radiation Therapy to the Head or Intrathecal Chemotherapy Plus High Dose Cytarabine in Preventing CNS Disease in Children With Acute Lymphoblastic Leukemia
5. Dexamethasone Compared With Prednisone During Induction Therapy and Methotrexate With or Without Leucovorin During Maintenance Therapy in Treating Patients With Newly Diagnosed High-Risk Acute Lymphoblastic Leukemia
Related Studies:
Other untreated childhood acute lymphoblastic leukemia Clinical Trials
Other New Hampshire Clinical Trials
Other Lebanon Clinical Trials
Combination Chemotherapy in Treating Children With Newly Diagnosed Acute Lymphoblastic Leukemia
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