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Combination Chemotherapy in Treating Children With Acute Lymphoblastic Leukemia Clinical Trials Information presented on Clinical Trials Search is not designed to be a substitute for certified medical advice, trips or professional assistance with a real medical doctor. We aren't docs. Always confer with your doctor about Combination Chemotherapy in Treating Children With Acute Lymphoblastic Leukemia conditions. Clinical Trials Search.org is a website committed to listing clinical research studies in human subjects. Combination Chemotherapy in Treating Children With Acute Lymphoblastic Leukemia Clinical research trials and Combination Chemotherapy in Treating Children With Acute Lymphoblastic Leukemia health trials happen in many of cities across the US. A clinical trial or clinical study is a research project with human volunteer subjects. Clinical drug trials and pharmaceutical clinical trials generally measure the effectualness of new does drugs. The intention of the studies / projects is to figure out particular human healthcare questions. Clinical trials are a popular manner for doctors, government agencies, and private sector corporations to detect cures for all forms of circumstances, like Combination Chemotherapy in Treating Children With Acute Lymphoblastic Leukemia. Combination Chemotherapy in Treating Children With Acute Lymphoblastic Leukemia Clinical Trials and other clinical trials allow for volunteers to undergo medical treatment options before they are available to the general public. Most times the subjects get treatment for free of charge, and occasionally they are paid for their time. Occasionally there is a cost for a Combination Chemotherapy in Treating Children With Acute Lymphoblastic Leukemia clinical trial. Subjects frequently get the best healthcare possible for their Combination Chemotherapy in Treating Children With Acute Lymphoblastic Leukemia condition. Hazards are a reality, however, and could include more or frequent mD visits, health risks (possibly life-jeopardizing), and/or the treatment being ineffectual. Trials are federally regulated with exacting guidelines to protect clinical trials patients.
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Home > "C" Clinical Trials Conditions > Combination Chemotherapy in Treating Children With Acute Lymphoblastic Leukemia  Combination Chemotherapy in Treating Children With Acute Lymphoblastic Leukemia
Combination Chemotherapy in Treating Children With Acute Lymphoblastic Leukemia
For Condition: B-cell childhood acute lymphoblastic leukemia,childhood acute lymphoblastic leukemia in remission
Status: Recruiting
Sponsor(s): Children's Oncology Group , National Cancer Institute (NCI)
Synopsis: RATIONALE: Drugs used in chemotherapy use different ways to stop cancer cells from dividing so they stop growing or die. Combining more than one drug may kill more cancer cells. It is not yet known which regimen of combination chemotherapy is more effective for childhood acute lymphoblastic leukemia. PURPOSE: Randomizedphase III trial to compare the effectiveness of different regimens of combination chemotherapy in treating children who have acute lymphoblastic leukemia.
Details: OBJECTIVES: - Compare the efficacy and toxicity of short methotrexate infusion vs longer infusion in patients with low-risk acute lymphoblastic leukemia. - Compare the efficacy of these regimens of methotrexate, with or without multidrug intensification, in these patients. OUTLINE: This is a randomized, multicenter study. Patients are stratified according to genetics (stratum 1: trisomy 4/10 but not TEL/AML1 vs stratum 2: TEL/AML1 with or without trisomy 4/10). All patients receive induction therapy (weeks 1-4) on another protocol (POG-9900). Stratum 1 - Consolidation therapy begins on week 5. Patients are randomized to arm I or II. - Arm I: Patients receive methotrexate (MTX) IV over 24 hours on day 1 and oral leucovorin calcium (CF) every 6 hours for 3 doses beginning 42 hours after initiation of MTX infusion during weeks 7, 10, 13, 16, and 19. - Arm II: Patients receive MTX IV over 4 hours on day 1 and oral CF as in arm I during weeks 7, 10, 13, 16, and 19. - Patients in arms I and II also receive MTX intrathecally (IT) on weeks 7, 10, 13, 16, 19, and 22; oral mercaptopurine (6-MP) daily on weeks 5-24; oral dexamethasone (DM) twice daily on days 1-7 of weeks 8 and 17; and vincristine (VCR) IV on day 1 of weeks 8, 9, 17, and 18. Stratum 2 - Consolidation therapy begins on week 5 and delayed intensification therapy begins on week 16. Patients are randomized to delayed intensification or no delayed intensification. Patients randomized to no delayed intensification are then randomized to consolidation therapy on arm I or II. Patients randomized to delayed intensification are then randomized to arm III or IV. Patients with trisomy 4/10 are not randomized to arms III and IV. - Arm III: Patients receive MTX IV and CF as in arm I on weeks 7, 10, 13, 24, 27, and 30. - Arm IV: Patients receive MTX IV and CF as in arm II on weeks 7, 10, 13, 24, 27, and 30. - Patients in arms III and IV also receive oral 6-MP daily on weeks 5-13 and then beginning on week 24 and continuing until the end of consolidation; MTX IT on weeks 7, 10, 13, 16, 20, 21, and 30; oral DM twice daily on days 1-7 of weeks 8, 16-18, and 28; VCR IV on day 1 of weeks 8, 9, 16-18, 28, and 29; pegaspargase intramuscularly on week 16; daunorubicin IV on day 1 of weeks 16-18; cyclophosphamide IV on day 1 of week 20; cytarabine IV or subcutaneously on days 2-5 of weeks 20 and 21; and oral thioguanine daily on days 1-14 of weeks 20 and 21. All patients then receive continuation therapy beginning on week 25 for arms I and II and week 33 for arms III and IV and continuing until week 130 for all arms. Continuation - Arms I and II: Patients receive oral 6-MP daily on weeks 25-130; oral DM twice a day on days 1-7 and VCR IV on days 1 and 8 during weeks 25, 41, 57, 73, 89, and 105; oral MTX weekly on weeks 25-130 (except during weeks of IT MTX); and MTX IT on weeks 25, 37, 49, 61, 73, 85, 97, and 109. - Arms III and IV: Patients receive oral 6-MP daily on weeks 33-130; oral DM twice a day on days 1-7 and VCR IV on days 1 and 8 during weeks 41, 57, 73, 89, and 105; oral MTX weekly on weeks 33-130 (except during weeks of IT MTX); and MTX IT on weeks 37, 49, 61, 73, 85, 97, and 109. Patients are followed every 2 months for 2 years, every 3 months for 1 year, every 6 months for 2 years, and then annually thereafter. PROJECTED ACCRUAL: A total 902 patients will be accrued for this study within 3.22 years.
Eligibility:
Study Type: Interventional, Treatment
Minimum Age/Maximum Age: 1 Year/9 Years
Genders: Both
Protocol Entry Criteria: DISEASE CHARACTERISTICS: - Diagnosis of B-cell precursor acute lymphoblastic leukemia - Registered on POG-9900 Classification Study - Registered within 7 days of documenting complete response (CR) after induction therapy on day 29 or, if 2 more weeks of induction are required, within 7 days of CR determination - Classified as low-risk: - WBC less than 50,000/mm^3 - Age 1 to 9 - No adverse translocations [E2A-PBX1, t(1;19) or BCR/ABL, t(9;22); and MLL rearrangements] - No CNS 3 disease (CSF WBC at least 5/mm^3 with blasts present) - No testicular disease - At least one of the following present: - TEL/AML1, t(12;21) - Simultaneous trisomy of chromosomes 4 and 10 PATIENT CHARACTERISTICS: Age: - 1 to 9 Performance status: - Not specified Life expectancy: - Not specified Hematopoietic: - See Disease Characteristics Hepatic: - Not specified Renal: - Not specified Other: - Not pregnant or nursing - Fertile patients must use effective contraception PRIOR CONCURRENT THERAPY: Biologic therapy - Not specified Chemotherapy - Not specified Endocrine therapy - Not specified Radiotherapy - Not specified Surgery - Not specified
Total Enrollment:
Location and Contact Information:
Overall Study Official:
PaulMartin, Study Chair, Duke Comprehensive Cancer Center
Children's Hospital of Southwest Florida *Recruiting*
Ft. Myers, Florida, 33908
United States
Recruiting Emad Salman 941-432-3333
Carilion Medical Center for Children *Recruiting*
Roanoke, Virginia, 24029
United States
Recruiting Joan Fisher 540-985-8055
University of Alabama at Birmingham Comprehensive Cancer Center *Recruiting*
Birmingham, Alabama, 35233
United States
Recruiting Robert Castleberry 205-939-9285
Arizona Cancer Center at University of Arizona Health Sciences Center *Recruiting*
Tucson, Arizona, 85724
United States
Recruiting Michael Graham 520-626-6044
Maine Children's Cancer Program *Recruiting*
Scarborough, Maine, 04074-9308
United States
Recruiting Craig Hurwitz 207-885-7565
Centre de Recherche du Centre Hospitalier de l'Universite Laval *Recruiting*
Sainte-Foy, Quebec, GIV 4G2
Canada
Recruiting Yvan Samson 418-656-4141
MBCCOP - LSU Health Sciences Center *Recruiting*
New Orleans, Louisiana, 70112
United States
Recruiting Jill Gilbert 504-568-5136
Rebecca and John Moores UCSD Cancer Center *Recruiting*
La Jolla, California, 92093-0658
United States
Recruiting Richard Kadota 858-657-7020
Rush-Presbyterian-St. Luke's Medical Center *Recruiting*
Chicago, Illinois, 60612
United States
Recruiting Allen Korenblit 312-942-5983
Blumenthal Cancer Center at Carolinas Medical Center *Recruiting*
Charlotte, North Carolina, 28232-2861
United States
Recruiting Daniel McMahon 704-355-1130
University of California Davis Cancer Center *Recruiting*
Sacramento, California, 95817
United States
Recruiting Theodore Zwerdling 916-734-2781
University of Massachusetts Memorial Medical Center - University Campus *Recruiting*
Worcester, Massachusetts, 01655
United States
Recruiting Ghazala Usmani 508-856-4225
St. Vincent Hospital *Recruiting*
Green Bay, Wisconsin, 54307-9070
United States
Recruiting Jon Brandt 920-433-8670
Saint Jude Midwest Affiliate *Recruiting*
Peoria, Illinois, 61637
United States
Recruiting John McCallister 309-624-4945
Roswell Park Cancer Institute *Recruiting*
Buffalo, New York, 14263-0001
United States
Recruiting Martin Brecher 716-845-2333
Floating Hospital for Children *Recruiting*
Boston, Massachusetts, 02111
United States
Recruiting Cynthia Kretschmar 617-636-5535
Presbyterian Healthcare *Recruiting*
Charlotte, North Carolina, 28233
United States
Recruiting Mark Mogul 704-384-1900
Warren Clinic *Recruiting*
Tulsa, Oklahoma, 74136
United States
Recruiting Martina Hum 918-494-2525 ext. 2557
Swiss Pediatric Oncology Group Bern *Recruiting*
Bern, , CH 3010
Switzerland
Recruiting Annette Ridolfi-Luethy 41-31-632-9372
Children's Hospital of Michigan *Recruiting*
Detroit, Michigan, 48201
United States
Recruiting Yaddanapudi Ravindranath 313-745-5649
Royal Children's Hospital *Recruiting*
Brisbane, Queensland, 4029
Australia
Recruiting Helen Irving 61-7-3636-8111
Academisch Ziekenhuis Groningen *Recruiting*
Groningen, , 9700 RB
Netherlands
Recruiting Willem Kamps 31-50-361-4213
Oklahoma University Medical Center at University of Oklahoma Health Sciences Center *Recruiting*
Oklahoma City, Oklahoma, 73126
United States
Recruiting William Meyer 405-271-4022
Nemours Children's Clinic *Recruiting*
Jacksonville, Florida, 32207
United States
Recruiting Eric Sandler 904-390-3793
James P. Wilmot Cancer Center at University of Rochester Medical Center *Recruiting*
Rochester, New York, 14642
United States
Recruiting Barbara Asselin 716-275-2981
McGill University Health Center - Montreal Children's Hospital *Recruiting*
Montreal, Quebec, H3G 1A4
Canada
Recruiting Carolyn Freeman 514-412-8040
Kaiser Permanente Medical Center - Santa Clara *Recruiting*
Santa Clara, California, 95051-5386
United States
Recruiting Carolyn Russo 408-236-5028
Simmons Cancer Center at University of Texas Southwestern Medical Center - Dallas *Recruiting*
Dallas, Texas, 75390-9063
United States
Recruiting Naomi Winick 214-648-3074
CCOP - Columbia River Oncology Program *Recruiting*
Portland, Oregon, 97225
United States
Recruiting Keith Lanier 503-216-6260
Children's Hospital of Greenville Hospital System *Recruiting*
Greenville, South Carolina, 29605
United States
Recruiting Cary Stroud 864-455-8898
Children's Hospital of Eastern Ontario *Recruiting*
Ottawa, Ontario, K1H 8L1
Canada
Recruiting Jacqueline Halton 613-737-7600 ext. 2370
University of Missouri - Columbia *Recruiting*
Columbia, Missouri, 65203
United States
Recruiting Katherine Kelly 573-882-3933
Rhode Island Hospital *Recruiting*
Providence, Rhode Island, 02818
United States
Recruiting William Ferguson 401-444-5171
Baptist Hospital of Miami *Recruiting*
Miami, Florida, 33176-2197
United States
Recruiting Doured Daghistani 786-596-1960
Sacred Heart Children's Hospital *Recruiting*
Pensacola, Florida, 32504
United States
Recruiting John Kelleher 850-505-4798
Children's Hospital at Westmead *Recruiting*
Westmead, New South Wales, 2145
Australia
Recruiting Geoffrey McCowage 61-2-9845-2122
Medical City Dallas Hospital *Recruiting*
Dallas, Texas, 75230
United States
Recruiting Carl Lenarsky 214-788-6647
St. Mary's Hospital *Recruiting*
West Palm Beach, Florida, 33407
United States
Recruiting Narayana Gowda 561-840-6125
University of Miami Sylvester Cancer Center *Recruiting*
Miami, Florida, 33136
United States
Recruiting Stuart Toledano 305-585-5635
Children's Hospital of New Orleans *Recruiting*
New Orleans, Louisiana, 70118
United States
Recruiting Rajasekharan Warrier 504-568-4561
Kaiser Permanente Medical Center/Kaiser Foundation Hospital - San Diego *Recruiting*
San Diego, California, 92120
United States
Recruiting Wellington Loh 619-516-6144
Nemours Children's Clinic-Orlando *Recruiting*
Orlando, Florida, 32806
United States
Recruiting Vincent Giusti 407-650-7230
Florida Hospital Cancer Institute *Recruiting*
Orlando, Florida, 32804
United States
Recruiting Jane Crofton 407-303-2090
Children's Memorial Hospital - Chicago *Recruiting*
Chicago, Illinois, 60614
United States
Recruiting Susan Cohn 773-880-4562
Tulane University School of Medicine *Recruiting*
New Orleans, Louisiana, 70112
United States
Recruiting Marshall Schorin 504-588-5412
Advocate Hope Children's Hospital *Recruiting*
Oak Lawn, Illinois, 60453
United States
Recruiting Sharad Salvi 708-346-4094
Cross Cancer Institute *Recruiting*
Edmonton, Alberta, T6G 1Z2
Canada
Recruiting Paul Grundy 780-432-8894
St. John Hospital and Medical Center *Recruiting*
Detroit, Michigan, 48236
United States
Recruiting Hadi Sawaf 313-343-3964
Hopital Sainte Justine *Recruiting*
Montreal, Quebec, H3T 1C5
Canada
Recruiting Albert Moghrabi 514-345-4969
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins *Recruiting*
Baltimore, Maryland, 21231-2410
United States
Recruiting Cindy Schwartz 410-955-2457
Tampa Children's Hospital *Recruiting*
Tampa, Florida, 33677-4227
United States
Recruiting Cameron Tebbi 813-870-4252
Ochsner Clinic Foundation *Recruiting*
New Orleans, Louisiana, 70121
United States
Recruiting Marquis Hodes 504-842-5230
All Children's Hospital *Recruiting*
St. Petersburg, Florida, 33701
United States
Recruiting Jerry Barbosa 727-892-4176
Beth Israel Medical Center - Singer Division *Recruiting*
New York City, New York, 10128
United States
Recruiting Jeffrey Allen 212-870-9407
Sutter Cancer Center *Recruiting*
Sacramento, California, 95816
United States
Recruiting Yisheng Lee 916-454-6700
Yale Comprehensive Cancer Center *Recruiting*
New Haven, Connecticut, 06520-8028
United States
Recruiting Jack Hoff 203-785-4095
St. Jude Children's Research Hospital *Recruiting*
Memphis, Tennessee, 38105-2794
United States
Recruiting Ching-Hon Pui 901-495-3335
CCOP - Scott and White Hospital *Recruiting*
Temple, Texas, 76508
United States
Recruiting Lucas Wong 254-724-7048
Duke Comprehensive Cancer Center *Recruiting*
Durham, North Carolina, 27710
United States
Recruiting Philip Breitfeld 919-684-3377
Eastern Maine Medical Center *Recruiting*
Bangor, Maine, 04401
United States
Recruiting Judith Allen 207-973-7520
West Virginia University Hospitals *Recruiting*
Morgantown, West Virginia, 26506-9300
United States
Recruiting Frank Keller 304-293-1217
Stanford Cancer Center at Stanford University Medical Center *Recruiting*
Stanford, California, 94305-5208
United States
Recruiting Michael Link 650-723-5535
West Virginia University - Robert C. Byrd Health Sciences Center - Charleston Division *Recruiting*
Charleston, West Virginia, 25302
United States
Recruiting Sanjeev Grover 304-388-1540
University of Arkansas for Medical Sciences *Recruiting*
Little Rock, Arkansas, 72205
United States
Recruiting David Becton 501-320-5650
Norris Cotton Cancer Center at Dartmouth Medical School *Recruiting*
Lebanon, New Hampshire, 03756
United States
Recruiting Eric Larsen 603-650-5541
Miami Children's Hospital *Recruiting*
Miami, Florida, 33155-4069
United States
Recruiting Enrique Escalon 305-662-8360
Cancer Research Center of Hawaii *Recruiting*
Honolulu, Hawaii, 96813
United States
Recruiting Robert Wilkinson 808-586-2979
Inova Fairfax Hospital *Recruiting*
Falls Church, Virginia, 22042-3300
United States
Recruiting Jay Greenberg 703-698-1110
Shands Cancer Center at the University of Florida Health Science Center *Recruiting*
Gainesville, Florida, 32610-0296
United States
Recruiting Stephen Hunger 352-392-5633
Royal Children's Hospital *Recruiting*
Parkville, Victoria, 3052
Australia
Recruiting David Ashley 61-39-345-5522
Naval Medical Center, Portsmouth *Recruiting*
Portsmouth, Virginia, 23708-5100
United States
Recruiting Paulette Bryant 804-398-5767
San Jorge Childrens Hospital *Recruiting*
Santurce, , 00912
Puerto Rico
Recruiting Luis Clavell 787-728-1575
McMaster Children's Hospital at Hamilton Health Sciences *Recruiting*
Hamilton, Ontario, L8N 3Z5
Canada
Recruiting Ronald Barr 905-521-2100 ext. 73464
Cook Children's Medical Center - Fort Worth *Recruiting*
Ft. Worth, Texas, 76104
United States
Recruiting Timothy Griffin 682-885-4020
Cancer Center at the University of Virginia *Recruiting*
Charlottesville, Virginia, 22908
United States
Recruiting Pedro de Alarcon 434-924-5105
Alberta Children's Hospital *Recruiting*
Calgary, Alberta, T2T 5C7
Canada
Recruiting Douglas Strother 403-943-7272
Comprehensive Cancer Center at Wake Forest University *Recruiting*
Winston Salem, North Carolina, 27157-1081
United States
Recruiting Thomas McLean 336-716-4324
Swiss Pediatric Oncology Group Geneva *Recruiting*
Geneva, , CH 1211
Switzerland
Recruiting Pierre Wacker 41-22-382-3311
Tripler Army Medical Center *Recruiting*
Honolulu, Hawaii, 96859-5000
United States
Recruiting Braden Shoupe 808-433-6057
Keesler Medical Center - Keesler Air Force Base *Recruiting*
Keesler AFB, Mississippi, 39534-2511
United States
Recruiting Wanda Salzer 228-377-6524
Texas Children's Cancer Center *Recruiting*
Houston, Texas, 77030-2399
United States
Recruiting C. Steuber 832-822-4200
San Antonio Military Pediatric Cancer and Blood Disorders Center *Recruiting*
Lackland Air Force Base, Texas, 78236
United States
Recruiting Aaron Pitney 210-292-5684
Leo W. Jenkins Cancer Center of University Health Systems of Eastern Carolina *Recruiting*
Greenville, North Carolina, 27858-4354
United States
Recruiting Sarah Strandjord 252-744-4676
Midwest Children's Cancer Center *Recruiting*
Milwaukee, Wisconsin, 53226
United States
Recruiting Bruce Camitta 414-456-4118
Hurley Medical Center *Recruiting*
Flint, Michigan, 48503
United States
Recruiting Susumu Inoue 810-762-7303
Marlene and Stewart Greenebaum Cancer Center, University of Maryland *Recruiting*
Baltimore, Maryland, 21201-1595
United States
Recruiting Neil Grossman 410-328-2808
University of New Mexico Cancer Research and Treatment Center *Recruiting*
Albuquerque, New Mexico, 87131
United States
Recruiting Jami Frost 505-272-4461
Vermont Cancer Center at University of Vermont *Recruiting*
Burlington, Vermont, 05401-3498
United States
Recruiting Alan Homans 802-847-2850
Children's Hospital and Health Center, San Diego *Recruiting*
San Diego, California, 92123-4282
United States
Recruiting Richard Kadota 858-966-5811
Broward General Medical Center *Recruiting*
Ft. Lauderdale, Florida, 33316
United States
Recruiting Rudolph Roskos 954-355-4527
University of Texas Medical Branch *Recruiting*
Galveston, Texas, 77555-0361
United States
Recruiting Kwesi Sackey 409-772-2341
Madigan Army Medical Center *Recruiting*
Tacoma, Washington, 98431-5000
United States
Recruiting Kelly Faucette 253-968-1864
Joe DiMaggio Children's Hospital at Memorial *Recruiting*
Hollywood, Florida, 33021
United States
Recruiting Iftikhar Hanif 954-986-2234
Center for Cancer Prevention and Care at Scott and White Clinic *Recruiting*
Temple, Texas, 76508
United States
Recruiting Lawrence Frankel 254-724-2006
University Hospital at State University of New York - Upstate Medical University *Recruiting*
Syracuse, New York, 13210
United States
Recruiting Ronald Dubowy 315-464-5294
Mission St. Joseph's Health System *Recruiting*
Asheville, North Carolina, 28801
United States
Recruiting Orren Beaty 823-213-5770
Driscoll Children's Hospital *Recruiting*
Corpus Christi, Texas, 78466
United States
Recruiting Judith Mullins 361-694-5311
CCOP - Wichita *Recruiting*
Wichita, Kansas, 67214-3882
United States
Recruiting David Rosen 316-268-5784
Kansas Cancer Institute at the University of Kansas Medical Center *Recruiting*
Kansas City, Kansas, 66160-7357
United States
Recruiting Robert Trueworthy 913-588-6340
Schneider Children's Hospital *Recruiting*
New Hyde Park, New York, 11042
United States
Recruiting Arlene Redner 718-470-3460
Wesley Medical Center *Recruiting*
Wichita, Kansas, 67214
United States
Recruiting David Rosen 316-962-2025
Legacy Emanuel Hospital and Health Center & Children's Hospital *Recruiting*
Portland, Oregon, 97227
United States
Recruiting Janice Olson 503-413-2200
Massachusetts General Hospital Cancer Center *Recruiting*
Boston, Massachusetts, 02114
United States
Recruiting Howard Weinstein 617-724-3315
Cardinal Glennon Children's Hospital *Recruiting*
St. Louis, Missouri, 63104
United States
Recruiting Dennis O'Connor 314-577-5638
Hollings Cancer Center at Medical University of South Carolina *Recruiting*
Charleston, South Carolina, 29425-0721
United States
Recruiting Julio Barredo 803-792-2957
East Tennessee State University Cancer Center at Johnson City Medical Center *Recruiting*
Johnson City, Tennessee, 37604
United States
Recruiting Sharon Castellino 423-433-6200
Long Island Cancer Center at Stony Brook University Hospital *Recruiting*
Stony Brook, New York, 11794
United States
Recruiting Robert Parker 631-689-6000
University of Texas Health Science Center at San Antonio *Recruiting*
San Antonio, Texas, 78207
United States
Recruiting Paul Thomas 210-704-3405
Via Christi Regional Medical Center *Recruiting*
Wichita, Kansas, 67214
United States
Recruiting David Rosen 316-268-5000
University of Mississippi Medical Center *Recruiting*
Jackson, Mississippi, 39216-4505
United States
Recruiting Dale Pullen 601-984-5220
Dana-Farber/Harvard Cancer Center at Dana Farber Cancer Institute *Recruiting*
Boston, Massachusetts, 02115
United States
Recruiting Holcombe Grier 617-632-3971
Cancer Center at Hackensack University Medical Center *Recruiting*
Hackensack, New Jersey, 07601
United States
Recruiting Michael Harris 201-996-5437
St. Christopher's Hospital for Children *Recruiting*
Philadelphia, Pennsylvania, 19134-1095
United States
Recruiting Gregory Halligan 215-427-5000
AFLAC Cancer Center and Blood Disorders Service of Children's Healthcare of Atlanta - Scottish Rite Campus *Recruiting*
Atlanta, Georgia, 30342
United States
Recruiting Stephen Lauer 404-250-2781
Mount Sinai School of Medicine *Recruiting*
New York City, New York, 10029
United States
Recruiting Elizabeth Raetz 212-241-7022
Massey Cancer Center at Virginia Commonwealth University *Recruiting*
Richmond, Virginia, 23298-0037
United States
Recruiting Edward Russell 804-828-0450
Hospital for Sick Children *Recruiting*
Toronto, Ontario, M5G 1X8
Canada
Recruiting Victor Blanchette 416-598-5852
Walter Reed Army Medical Center *Recruiting*
Washington D.C., District of Columbia, 20307-5000
United States
Recruiting E. Edwards 202-782-9449
CCOP - Marshfield Clinic Research Foundation *Recruiting*
Marshfield, Wisconsin, 54449
United States
Recruiting Tarit Banerjee 715-387-5134
Washington University Medical Center *Recruiting*
St. Louis, Missouri, 63105
United States
Recruiting Lori Luchtman-Jones 314-454-6018
University of South Alabama Medical Center *Recruiting*
Mobile, Alabama, 36604
United States
Recruiting Yih-Ming Yang 251-405-5115
Additional Information:
Study ID Numbers: CDR0000067657; COG-P9904,POG-9904
Study Start Date:
Record last reviewed: May 2003
Additional information available at: clinicaltrials.gov
Clinicaltrials.gov Reference link: NCT00005585
Other B-Cell Childhood Acute Lymphoblastic Leukemia Studies:
1. Combination Chemotherapy in Treating Children With Acute Lymphoblastic Leukemia
2. Dexamethasone Compared With Prednisone During Induction Therapy and Methotrexate With or Without Leucovorin During Maintenance Therapy in Treating Patients With Newly Diagnosed High-Risk Acute Lymphoblastic Leukemia
3. Combination Chemotherapy in Treating Patients With Non-Hodgkin's Lymphoma or Acute Lymphocytic Leukemia
4. Combination Chemotherapy and Rituximab in Treating Young Patients With Recurrent or Refractory Non-Hodgkin's Lymphoma or Acute Lymphoblastic Leukemia
5. Combination Chemotherapy in Treating Children With Very High Risk Acute Lymphocytic Leukemia
Related Studies:
Other B-cell childhood acute lymphoblastic leukemia Clinical Trials
Other North Carolina Clinical Trials
Other Asheville Clinical Trials
Combination Chemotherapy in Treating Children With Acute Lymphoblastic Leukemia
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