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Home > "C" Clinical Trials Conditions > Collaborative Study of 1,3 Butadiene Biomarkers Collaborative Study of 1,3 Butadiene Biomarkers
Collaborative Study of 1,3 Butadiene Biomarkers
For Condition: Cancer
Status: Recruiting
Sponsor(s): National Institute of Environmental Health Sciences (NIEHS) ,
Synopsis: Butadiene is a suspect human carcinogen to which most people are exposed daily. Exposures are difficult to measure by air sampling. This study examines the relationship between air levels and several biomarkers of exposure. Biomarkers are substances analyzed in human tissues or waste products. Adducts are materials formed when a chemical reacts with a biological material. In this study we are looking at biomarkers in the blood: hemoglobin and DNA adducts, and urinary metabolites. If a strong relationship is found then the amounts of biomarkers in a person's blood or urine can tell us how much they have been exposed. The tests are being conducted on petrochemical workers who have a wide range of exposures to butadiene. An international group of investigators is conducting the study.
Details:
Eligibility:
Study Type: Observational, Natural History, Longitudinal, Defined Population, Prospective Study
Minimum Age/Maximum Age: 19 Years/65 Years
Genders: Both
Protocol Entry Criteria: Healthy adults without metabolic disorders
Total Enrollment: 80
Location and Contact Information:
Harvard School of Public Health *Recruiting*
Boston, Massachusetts, 02115
United States
Recruiting Thomas Smith 617-432-3315
National Chung Kung University *Recruiting*
Tainan, ,
Taiwan, Province of China
Recruiting Ho-Yuan Chang
Additional Information:
Study ID Numbers: 9401-CP-001;
Study Start Date: July 1999
Record last reviewed: July 2000
Additional information available at: clinicaltrials.gov
Clinicaltrials.gov Reference link: NCT00023140
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Collaborative Study of 1,3 Butadiene Biomarkers
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