|
Clinical Evaluation of a Laser Heated, Fiberoptic-Coupled Radiation Dose Verification System Clinical Trials Info presented on Clinical Trials Search isn't intended to be a substitute for qualified medical advice, visits or professional assistance by using a real mD. We are not docs. Always confer with your physician about Clinical Evaluation of a Laser Heated, Fiberoptic-Coupled Radiation Dose Verification System conditions. Clinical Trials Search.org is a website committed to listing clinical research studies in human subjects. Clinical Evaluation of a Laser Heated, Fiberoptic-Coupled Radiation Dose Verification System Clinical research trials and Clinical Evaluation of a Laser Heated, Fiberoptic-Coupled Radiation Dose Verification System health trials occur in many of cities throughout the US. A clinical trial or clinical study is a research project with human volunteer subjects. Clinical drug trials and pharmaceutical clinical trials generally evaluate the effectivity of new does drugs. The intent of the studies / undertakings is to resolve particular human health questions. Clinical trials are a popular way for physicians, government agencies, and private sector companies to detect remedies for all sorts of conditions, including Clinical Evaluation of a Laser Heated, Fiberoptic-Coupled Radiation Dose Verification System. Clinical Evaluation of a Laser Heated, Fiberoptic-Coupled Radiation Dose Verification System Clinical Trials and other clinical trials permit volunteers to obtain healthcare treatment alternatives before they are available to the masses. Most times the participants undergo professional assistance for without cost, and occasionally they are compensated for their time. Occasionally there is a cost for a Clinical Evaluation of a Laser Heated, Fiberoptic-Coupled Radiation Dose Verification System clinical trial. Test subjects typically receive the most expert healthcare available for their Clinical Evaluation of a Laser Heated, Fiberoptic-Coupled Radiation Dose Verification System condition. Dangers are a reality, however, and may include more or frequent mD visits, healthcare dangers (perhaps life-endangering), and/or the treatment being ineffectual. Trials are federally regulated with rigid guidelines to protect clinical trials patients.
|
|
|
|
|
|
|
Home > "C" Clinical Trials Conditions > Clinical Evaluation of a Laser Heated, Fiberoptic-Coupled Radiation Dose Verification System  Clinical Evaluation of a Laser Heated, Fiberoptic-Coupled Radiation Dose Verification System
Clinical Evaluation of a Laser Heated, Fiberoptic-Coupled Radiation Dose Verification System
For Condition: Neoplasm
Status: Recruiting
Sponsor(s): National Cancer Institute (NCI) ,
Synopsis: We propose to determine the response of a newly developed laser heated, vycor glass fiberoptic radiation dosimetry system to ionizing radiation in a clinical radiotherapy environment. Present systems measure only total dose or have limitations, such as instability, non-linearity, excessive size or a decoupled measurement system, making them unsuitable in a variety of clinical applications. This fiberoptic coupled dosimetry system is a new and innovative technology application which allows on-line measurement of instantaneous dose rate and total dose never before achievable. It offers a clear advantage in patient treatment delivery, allowing on-line corrections essential to a new generation of radiotherapy treatment machines with development of beam intensity modulation as an adjunct to 3D conformal therapy. It also has the advantage of submillimeter size and is minimally invasive, making it ideal for brachytherapy. This system has the potential for stable, accurate, reproducible, clinically feasible measurements of total dose and dose rate. The output of this system will be measured under various clinical conditions encountered in a clinical setting and compared against existing thermolumeniscent and diode dosimetry standards. Initial measurements will use a tissue equivalent phantom for depth dose and accuracy measurements. Additional studies will include dosimetric measurements of routine clinical treatment setups on patients receiving therapeutic irradiation.
Details: We propose to determine the response of a newly developed laser heated, vycor glass fiberoptic radiation dosimetry system to ionizing radiation in a clinical radiotherapy environment. Present systems measure only total dose or have limitations, such as instability, non-linearity, excessive size or a decoupled measurement system, making them unsuitable in a variety of clinical applications. This fiberoptic coupled dosimetry system is a new and innovative technology application which allows on-line measurement of instantaneous dose rate and total dose never before achievable. It offers a clear advantage in patient treatment delivery, allowing on-line corrections essential to a new generation of radiotherapy treatment machines with development of beam intensity modulation as an adjunct to 3D conformal therapy. It also has the advantage of submillimeter size and is minimally invasive, making it ideal for brachytherapy. This system has the potential for stable, accurate, reproducible, clinically feasible measurements of total dose and dose rate. The output of this system will be measured under various clinical conditions encountered in a clinical setting and compared against existing thermolumeniscent and diode dosimetry standards. Initial measurements will use a tissue equivalent phantom for depth dose and accuracy measurements. Additional studies will include dosimetric measurements of routine clinical treatment setups on patients receiving therapeutic irradiation.
Eligibility:
Study Type: Interventional, Treatment, Safety
Minimum Age/Maximum Age: /
Genders: Both
Protocol Entry Criteria: INCLUSION CRITERIA: Patients receiving either external beam radiotherapy or a radioactive implant under established primary clinical protocols at the NCI or the National Naval Medical Center. Patients must be willing to have the additional measurements performed and sign an informed consent. EXCLUSION CRITERIA: Pediatric and cognitively impaired subjects will not be eligible for this study.
Total Enrollment: 20
Location and Contact Information:
National Cancer Institute (NCI) *Recruiting*
Bethesda, Maryland, 20892
United States
Recruiting Clinical Support Center/NCI 1-888-624-1937
Additional Information:
Study ID Numbers: 970129; 97-C-0129
Study Start Date: July 17, 1997
Record last reviewed: April 1, 2004
Additional information available at: clinicaltrials.gov
Clinicaltrials.gov Reference link: NCT00026871
Other Neoplasm Studies:
1. A Pilot Study of Oxaliplatin in Combination with Capecitabine in Adult Cancer Patients
2. Phase I Trial of a Four Hour Infusion of Depsipeptide (NSC 630176) Given on Days 1 and 5 of a 21 Day Cycle in Patients with Refractory Neoplasms
3. Clinical Evaluation of a Laser Heated, Fiberoptic-Coupled Radiation Dose Verification System
4. Cellular Immunotherapy with Autologous T Lymphocytes Stimulated with the Patient's Tumor-Specific Mutated Ras Peptides
5. Evaluation for NCI Radiation Oncology Branch Clinical Research Protocols
Related Studies:
Other Neoplasm Clinical Trials
Other Maryland Clinical Trials
Other Bethesda Clinical Trials
Clinical Evaluation of a Laser Heated, Fiberoptic-Coupled Radiation Dose Verification System
|
|
|
|
|
|
|
|
