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Home > "C" Clinical Trials Conditions > Characteristics of Idiopathic Familial Speech Disorders Characteristics of Idiopathic Familial Speech Disorders
Characteristics of Idiopathic Familial Speech Disorders
For Condition: Developmental Articulation Disorder,Speech Disorder,Stuttering
Status: Recruiting
Sponsor(s): National Institute of Neurological Disorders and Stroke (NINDS) ,
Synopsis: According to studies, speech disorders with unknown causes (idiopathic) affect approximately 5% of the population at some point in their life. Some of these disorders like, stuttering and cluttering, are known for being detected early, during speech development. Stuttering is characterized by sound and syllable repetitions and consonant/vowel prolongations. When stuttering is moderate to severe, it can interfere with a person's job and social activities. Speech articulation disorders are characterized by omissions, or substitutions of speech sounds. The speech of a person who clutters is often difficult to understand. People are often unaware of the errors they make when speaking causing treatment of the condition to be very difficult. The purpose of this research is to study an extended family whose members exhibit a pure form of speech articulation disorders In addition, the study will use data and information gathered from the study and use it to develop guidelines (criteria) for defining and differentiating patients with speech disorders.
Details: The purpose of this protocol is to examine factors involved in the development of speech disorders -- stuttering and familial phonological processing disorder. Both disorders are developmental and occur during the critical period of speech development between 2.5 and 12 years of age. The majority of children affected with stuttering recover spontaneously during the critical period. Because of previous difficulties with definitions of cluttering, we have renamed the syndrome we are comparing with stuttering as a familial phonological processing disorder (FPPD). When symptoms persist, both stuttering and FPPD become life long chronic disorders. Our purpose is to determine which factors are involved in the development of these disorders and are associated with a familial pattern of inheritance.
Eligibility:
Study Type: Observational, Natural History
Minimum Age/Maximum Age: /
Genders: Both
Protocol Entry Criteria: INCLUSION CRITERIA: Developmental stuttering with onset prior to puberty with or without subsequent recovery. Developmental phonological disorders includes speech sound omissions or errors during conversational speech with poor error awareness with or without subsequent recovery. EXCLUSION CRITERIA: Individuals who developed stuttering following brain injury.
Total Enrollment: 375
Location and Contact Information:
National Institute of Neurological Disorders and Stroke (NINDS) *Recruiting*
Bethesda, Maryland, 20892
United States
Recruiting Patient and Public Liaison Office 1-800-411-1222
Additional Information:
Study ID Numbers: 960088; 96-N-0088
Study Start Date: May 22, 1996
Record last reviewed: July 1, 2003
Additional information available at: clinicaltrials.gov
Clinicaltrials.gov Reference link: NCT00001551
Other Stuttering Studies:
1. Characteristics of Idiopathic Familial Speech Disorders
2. Study of Brain Activity during Speech Production and Speech Perception
Related Studies:
Other Stuttering Clinical Trials
Other Maryland Clinical Trials
Other Bethesda Clinical Trials
Characteristics of Idiopathic Familial Speech Disorders
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