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Carperitide in Acute Respiratory Distress Syndrome (ARDS) Clinical Trials Facts presented on Clinical Trials Search isn't designed to be a substitute for proven healthcare advice, calls or treatment using a real mD. We aren't mDs. Always confer with your physician on Carperitide in Acute Respiratory Distress Syndrome (ARDS) conditions. Clinical Trials Search.org is a website dedicated to listing clinical research studies in human subjects. Carperitide in Acute Respiratory Distress Syndrome (ARDS) Clinical research trials and Carperitide in Acute Respiratory Distress Syndrome (ARDS) healthcare trials happen in a lot of of localities across the United States of America. A clinical trial or clinical study is a research project with human volunteer subjects. Clinical drug trials and pharmaceutical clinical trials generally measure the potency of new drugs. The aim of the studies / undertakings is to answer particular human medical questions. Clinical trials are a popular manner for doctors, government agencies, and private sector corporations to discover remedies for all kinds of circumstances, such as Carperitide in Acute Respiratory Distress Syndrome (ARDS). Carperitide in Acute Respiratory Distress Syndrome (ARDS) Clinical Trials and other clinical trials allow volunteers to get healthcare treatment alternatives before they are available to the general public. Most times the participants receive treatment for without cost, and occasionally they are paid for their time. Sometimes there is a cost for a Carperitide in Acute Respiratory Distress Syndrome (ARDS) clinical trial. Human subjects often receive the most effective healthcare possible for their Carperitide in Acute Respiratory Distress Syndrome (ARDS) condition. Risks are a reality, nonetheless, and may include more or frequent dr. calls, healthcare hazards (perhaps life-threatening), and/or the treatment being ineffective. Trials are federally governed with rigorous guidelines to protect clinical trials subjects.

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Carperitide in Acute Respiratory Distress Syndrome (ARDS)



Carperitide in Acute Respiratory Distress Syndrome (ARDS)

For Condition: Respiratory Distress Syndrome
Status: No longer recruiting
Sponsor(s): Suntory Pharmaceutical ,
Synopsis: The purpose of this study is to determine whether Carperitide is safe and effective in the management of Acute Respiratory Distress Syndrome (ARDS).
Details: Acute respiratory distress syndrome (ARDS is a severe form of acute lung injury. ARDS is characterized by an increase in pulmonary vascular permeability resulting from a non-cardiogenic cause, leading to an increased vascular water volume, pulmonary inflammation, and severe hypoxemia. Conventional therapy for ARDS is primarily respiratory management by mechanical ventilation using positive end-expiratory pressure (PEEP). Mechanical ventilation is the major management concern in patients with ARDS, due to its higher risk of infections and morbidity. Treatment with Carperitide may reduce time on the ventilator by reducing pulmonary edema and by improving gas exchange. The results of Carperitide studies in animals and humans support the idea that the hormone will be effective in managing the acute pulmonary complications and hypoxemia seen in ARDS.
Eligibility:
Study Type:  Interventional, Treatment, Randomized, Double-Blind, Placebo Control, Parallel Assignment, Safety/Efficacy Study
Minimum Age/Maximum Age: 18 Years/
Genders: Both
Protocol Entry Criteria: Inclusion: In order to participate in the study, patients must: - be 18 years or older - have an acceptable PF ratio - have adequate fluid volume - be intubated less than 7 days Exclusion: In order to participate in the study, patients must not meet any of the following criteria: - be moribund - be immunocompromised - have pneumonia (caused by Pneumocystis carinii) - have recieved another investigational drug or device within the last 30 days - have a Do not Resuscitate order
Total Enrollment: 

Location and Contact Information:


Additional Information:
Study ID Numbers:  SPI-001; 
Study Start Date: December 1999
Record last reviewed: November 2002
Additional information available at: clinicaltrials.gov
Clinicaltrials.gov Reference link: NCT00030121

Other Respiratory Distress Syndrome Studies:
1. Early Inhaled Nitric Oxide for Respiratory Failure in Newborns

2. Epidemiology of Surfactant Protein-B Deficiency

3. Impact of Surfactant's Availability on Newborns

4. Phase III Randomized, Double-Blind, Placebo-Controlled Study of Antenatal Thyrotropin-Releasing Hormone in Pregnant Women with Threatened Premature Delivery

5. Study of the Pathobiology of Bronchopulmonary Dysplasia in Newborns

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