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Buprenorphine/Naloxone Treatment for Opioid Dependence-Experiment II-1 - 4



Buprenorphine/Naloxone Treatment for Opioid Dependence-Experiment II-1 - 4

For Condition: Heroin Dependence,Opioid-Related Disorders
Status: Completed
Sponsor(s): National Institute on Drug Abuse (NIDA) , University of Colorado
Synopsis: To assess the abuse liability and examine the reinforcing effects of intravenous buprenorphine and buprenorphine/naloxone combinations in buprenorphine-naloxone maintained volunteers
Details: Ongoing study - results not available at this time
Eligibility:
Study Type:  Interventional, Treatment, Double-Blind, Placebo Control
Minimum Age/Maximum Age: 18 Years/65 Years
Genders: Both
Protocol Entry Criteria: Inclusion Criteria: Individuals must be at least 18 yrs of age, currently opioid dependent and meet FDA critera for narcotic maintenance treatment. Co-morbid substance abuse or dependence disorders may also be present. Individuals must be healthy despite drug dependency and have a history of IV opioid use. Exclusion Criteria: Individuals with evidence of ant active DSM-IV Axis I psychiatric disorder (e.g. psychosis, manic-depressive illness, organic psychiatric disorders), significant medical illness (e.g. liver or cardiovascular disease) or pregnant female subjects are excluded from study participation.
Total Enrollment: 0

Location and Contact Information:

Overall Study Official:
LeslieAmass,  Principal Investigator,  University of Colorado

University of Colorado Health Sciences Center
Denver,  Colorado,  80206
United States
 


Additional Information:
Study ID Numbers:  NIDA-11160-4;  R01-11160-4
Study Start Date: April 1999
Record last reviewed: April 1999
Additional information available at: clinicaltrials.gov
Clinicaltrials.gov Reference link: NCT00000329

Other Heroin Dependence Studies:
1. Expanded Steady-State Pharmacokinetic Study, Comparing Liquid and Tablet Buprenorphine Formulations - 5

2. Counseling Conditions for Thrice Weekly Buprenorphine in a Primary Care Clinic - 1

3. Buprenorphine/Naloxone Treatment for Opioid Dependence-Experiment I(2) - 2

4. Buprenorphine/Naloxone Treatment for Opioid Dependence-Experiment II-1 - 4

5. CS1008 A&B Eff/Safety trial of BUP/NX for the Treatment of Opiate Dependence - 1

Related Studies:

Other Heroin Dependence Clinical Trials
Other Colorado Clinical Trials
Other Denver Clinical Trials

Buprenorphine/Naloxone Treatment for Opioid Dependence-Experiment II-1 - 4
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