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Home > "B" Clinical Trials Conditions > Brain Tissue Collection for Neuropathological Studies  Brain Tissue Collection for Neuropathological Studies
Brain Tissue Collection for Neuropathological Studies
For Condition: Bipolar Disorder,Huntington Disease,Schizophrenia,Tourette Syndrome,Dementia
Status: Recruiting
Sponsor(s): National Institute of Mental Health (NIMH) ,
Synopsis: The purpose of this study is to collect and study the brain tissue of deceased individuals to learn more about the nervous system and mental disorders. Information gained from donated tissue may lead to better treatments and potential cures for nervous system and mental disorders. This study will ask relatives of deceased individuals to donate the brains of their deceased relatives to allow further study of neurological and psychiatric disorders.
Details: The knowledge of how affected tissue deviates from normal control tissue is an integral part of fully understanding a neurological or psychiatric disorder. The purpose of this protocol is to establish a coordinating program with the pathology departments of the Washington, D.C. and metropolitan area hospitals and local medical examiner's offices for the donation of brain tissue.
Eligibility:
Study Type: Observational, Natural History
Minimum Age/Maximum Age: /
Genders: Both
Protocol Entry Criteria: INCLUSION CRITERIA: Individuals suffering from a variety of neuropsychiatric disorders, especially schizophrenia, but also Huntington's chorea, suicide, manic-depressive illness, depression, Tourette's Syndrome, drug addictions (PCP, cocaine, alcohol, heroin or the like) and any form of dementia. Brain tissue from afflicted individuals is needed for the study. Brains (fresh or preserved tissue) from normal individuals without a history of neuropsychiatric disease.
Total Enrollment: 1250
Location and Contact Information:
National Institute of Mental Health (NIMH) *Recruiting*
Bethesda, Maryland, 20892
United States
Recruiting Joel Kleinman 3014027909
Additional Information:
Study ID Numbers: 900142; 90-M-0142
Study Start Date: May 29, 1990
Record last reviewed: May 11, 2003
Additional information available at: clinicaltrials.gov
Clinicaltrials.gov Reference link: NCT00001260
Other Dementia Studies:
1. Magnetic Resonance Spectroscopy to Evaluate Tourette's Syndrome
2. Study of GABA-A receptors in the Generation of Tics in Patients with Tourette's Syndrome
3. Brain Tissue Collection for Neuropathological Studies
4. Phase II Pilot Controlled Study of Short vs Longer Term Pimozide (Orap) Therapy in Tourette Syndrome
5. Brain Dynamics Involved in Generating Tics and Controlling Voluntary Movement
Related Studies:
Other Dementia Clinical Trials
Other Maryland Clinical Trials
Other Bethesda Clinical Trials
Brain Tissue Collection for Neuropathological Studies
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