|
Brain Imaging - Acupuncture and Osteoarthritis Clinical Trials Resources presented on Clinical Trials Search is not meant to be a substitute for proven health advice, calls or treatment with a real medical. We aren't mDs. Always consult your doctor on Brain Imaging - Acupuncture and Osteoarthritis conditions. Clinical Trials Search.org is a website dedicated to listing clinical research studies in human subjects. Brain Imaging - Acupuncture and Osteoarthritis Clinical research trials and Brain Imaging - Acupuncture and Osteoarthritis healthcare trials take place in a lot of of localities throughout the U.S.. A clinical trial or clinical study is a research project with human volunteer subjects. Clinical drug trials and pharmaceutical clinical trials typically assess the effectiveness of new does drugs. The function of the studies / projects is to figure out specific human medical questions. Clinical trials are a popular means for doctors, government agencies, and private sector corporations to find cures for all varieties of conditions, like Brain Imaging - Acupuncture and Osteoarthritis. Brain Imaging - Acupuncture and Osteoarthritis Clinical Trials and other clinical trials allow volunteers to access health treatment options before they are available to the masses. Many times the subjects receive professional assistance for free, and every now and again they are compensated for their time. Sometimes there is a cost for a Brain Imaging - Acupuncture and Osteoarthritis clinical trial. Human subjects often obtain the finest healthcare possible for their Brain Imaging - Acupuncture and Osteoarthritis condition. Hazards are a reality, nevertheless, and might include additional or frequent dr. calls, health hazards (potentially life-jeopardizing), and/or the treatment being uneffective. Trials are federally regulated with stern guidelines to protect clinical trials patients.
|
|
|
|
|
|
|
Home > "B" Clinical Trials Conditions > Brain Imaging - Acupuncture and Osteoarthritis  Brain Imaging - Acupuncture and Osteoarthritis
Brain Imaging - Acupuncture and Osteoarthritis
For Condition: Osteoarthritis
Status: Not yet recruiting
Sponsor(s): National Center for Complementary and Alternative Medicine (NCCAM) ,
Synopsis: The goal of this study is to use single photon emission computed tomography (SPECT) and functional magnetic resonance imaging (f-MRI) of the brain to study the response of both normal participants and participants with Osteoarthritis of the knee to acupuncture.
Details: Recent experimental studies in both animal and humans have begun to demonstrate some measureable physiologic effects that are associated with acupuncture, suggesting the possibility of a neurophysiologic explanation. In addition, brain research continues to uncover a complex set of endogenous neurologic control systems, such that it has become clear that the brain plays a major role in the modulation of pain perception and control. If acupuncture can be demonstrated to have a consistent effect on specific areas of the brain, it will become possible to explore the potential efficacy of acupuncture based on measurable neurophysiologic responses.
Eligibility:
Study Type: Interventional, Diagnostic, Randomized, Single Blind, Active Control, Crossover Assignment, Pharmacodynamics Study
Minimum Age/Maximum Age: 40 Years/
Genders: Both
Protocol Entry Criteria: Inclusion criteria: - Seen in an outpatient clinical setting - Have active knee OA of >6 months including Kellgren x-ray changes >2 from an x-ray report <12 months old or new x-ray interpretation - Moderate unilateral only pain (average >4/10 on a 0-10 likert scale) for more than 5 out of 7 days - Have the capacity to understand the requirements of the study and complete the baseline studies in a reasonable time frame, as determined by the interviewer Exclusion criteria: - Having had acupuncture before (must be acupuncture naïve) - Any history of claustrophobia that could affect the subject’s ability to tolerate the f-MRI study - Hip or ankle disease by history or exam severe enough to cause pain >2/10 daily - Bleeding disorder or current use of warfarin or heparin by patient history - Other primary causes of chronic knee pain, per the referring physician, including chondromalacia patella, torn meniscus or ligament injury.
Total Enrollment: 32
Location and Contact Information:
Overall Study Official:
JohnFarrar, Principal Investigator, University of Pennsylvania
Hospital of the University of Pennsylvania
Philadelphia, Pennsylvania, 19104-4283
United States
Andrew Newberg 215-662-3014
Additional Information:
Study ID Numbers: R21 AT000960-01A1;
Study Start Date: January 2004
Record last reviewed: October 2003
Additional information available at: clinicaltrials.gov
Clinicaltrials.gov Reference link: NCT00070824
Other Osteoarthritis Studies:
1. Doxycycline and OA Progression
2. Osteoarthritis Initiative (OAI): A Knee Health Study
3. Knee Stability Training for Knee Osteoarthritis (OA)
4. Glucosamine/Chondroitin Arthritis Intervention Trial (GAIT)
5. Efficacy of Acupuncture with Physical Therapy for Knee Osteo-Arthritis
Related Studies:
Other Osteoarthritis Clinical Trials
Other Pennsylvania Clinical Trials
Other Philadelphia Clinical Trials
Brain Imaging - Acupuncture and Osteoarthritis
|
|
|
|
|
|
|
|
