|
Brain Function in Children Previously Treated on Clinical Trials POG-9605 and POG-9201 Clinical Trials Information presented on Clinical Trials Search is not designed to be a substitute for proven healthcare advice, travels to or treatment by using a genuine medical doctor. We are not physicians. Always confer with your doctor on Brain Function in Children Previously Treated on Clinical Trials POG-9605 and POG-9201 conditions. Clinical Trials Search.org is a site devoted to listing clinical research studies in human subjects. Brain Function in Children Previously Treated on Clinical Trials POG-9605 and POG-9201 Clinical research trials and Brain Function in Children Previously Treated on Clinical Trials POG-9605 and POG-9201 healthcare trials take place in many of cities across the United States of America. A clinical trial or clinical study is a research project with human volunteer subjects. Clinical drug trials and pharmaceutical clinical trials generally evaluate the effectiveness of new drugs. The function of the studies / undertakings is to answer specific human medical questions. Clinical trials are a popular means for mDs, government agencies, and private sector companies to find treatments for all forms of conditions, including Brain Function in Children Previously Treated on Clinical Trials POG-9605 and POG-9201. Brain Function in Children Previously Treated on Clinical Trials POG-9605 and POG-9201 Clinical Trials and other clinical trials allow for volunteers to access medical treatment alternatives before they are available to the masses. Many times the test subjects undergo treatment for without cost, and occasionally they are compensated for their time. Occasionally there is a cost for a Brain Function in Children Previously Treated on Clinical Trials POG-9605 and POG-9201 clinical trial. Test subjects oftentimes recieve the best healthcare possible for their Brain Function in Children Previously Treated on Clinical Trials POG-9605 and POG-9201 condition. Hazards are a reality, nonetheless, and might include additional or frequent doctor trips, healthcare hazards (perhaps life-jeopardizing), and/or the treatment being ineffective. Trials are federally regulated with rigid guidelines to protect clinical trials subjects.
|
|
|
|
|
|
|
Home > "B" Clinical Trials Conditions > Brain Function in Children Previously Treated on Clinical Trials POG-9605 and POG-9201  Brain Function in Children Previously Treated on Clinical Trials POG-9605 and POG-9201
Brain Function in Children Previously Treated on Clinical Trials POG-9605 and POG-9201
For Condition: neurotoxicity,long-term effects secondary to cancer therapy in children
Status: Recruiting
Sponsor(s): Children's Oncology Group , National Cancer Institute (NCI)
Synopsis: RATIONALE: Assessing the effects of methotrexate on brain function in children may improve the ability to plan treatment and decrease side effects. PURPOSE: Clinical trial to compare brain function of children who have been previously treated with methotrexate.
Details: OBJECTIVES: - Compare the incidence of neuropsychological abnormalities and leukoencephalopathy in children previously treated with methotrexate on protocols POG-9605 versus POG-9201. OUTLINE: This is a multicenter study. More than 3 years after completion of therapy, patients undergo 9 different tests to assess intelligence, memory, learning, attention, concentration, processing of information, functioning, and visual-motor integration. Patients also undergo MRI of the head. PROJECTED ACCRUAL: A total of 30-54 patients previously treated on protocol POG-9201 will be accrued for this study. A total of 60-108 patients previously treated on protocol POG-9605 will be accrued for this study.
Eligibility:
Study Type: Interventional, Treatment
Minimum Age/Maximum Age: 1 Year/9 Years
Genders: Both
Protocol Entry Criteria: DISEASE CHARACTERISTICS: - Previously enrolled on POG-9201 or POG-9605 - Good prognosis by NCI risk (9201 and 9605 stratum 1) - Eligible for the therapeutic study - Completed therapy by 12/31/2000 - No CNS3 at diagnosis - No relapsed disease PATIENT CHARACTERISTICS: Age: - 1 to 9 at diagnosis Performance status: - Not specified Life expectancy: - Not specified Hematopoietic: - Not specified Hepatic: - Not specified Renal: - Not specified Other: - No Down syndrome PRIOR CONCURRENT THERAPY: Biologic therapy - Not specified Chemotherapy - Not specified Endocrine therapy - Not specified Radiotherapy - Not specified Surgery - Not specified Other - See Disease Characteristics
Total Enrollment:
Location and Contact Information:
Overall Study Official:
PatriciaDuffner, Study Chair, Women and Children's Hospital of Buffalo
Baptist Hospital of Miami *Recruiting*
Miami, Florida, 33176-2197
United States
Recruiting Doured Daghistani 786-596-1960
Joe DiMaggio Children's Hospital at Memorial *Recruiting*
Hollywood, Florida, 33021
United States
Recruiting Iftikhar Hanif 954-986-2234
MBCCOP - LSU Health Sciences Center *Recruiting*
New Orleans, Louisiana, 70112
United States
Recruiting Jill Gilbert 504-568-5136
Madigan Army Medical Center *Recruiting*
Tacoma, Washington, 98431-5000
United States
Recruiting Kelly Faucette 253-968-1864
Children's Hospital of Denver *Recruiting*
Denver, Colorado, 80218-1088
United States
Recruiting Roger Giller 303-861-6892
Midwest Children's Cancer Center *Recruiting*
Milwaukee, Wisconsin, 53226
United States
Recruiting Bruce Camitta 414-456-4118
CCOP - Scott and White Hospital *Recruiting*
Temple, Texas, 76508
United States
Recruiting Lucas Wong 254-724-7048
Jackson Memorial Hospital *Recruiting*
Miami, Florida, 33136
United States
Recruiting Stuart Toledano 305-585-5635
CCOP - Columbia River Oncology Program *Recruiting*
Portland, Oregon, 97225
United States
Recruiting Keith Lanier 503-216-6260
St. Mary's Hospital *Recruiting*
West Palm Beach, Florida, 33407
United States
Recruiting Narayana Gowda 561-840-6125
Hollings Cancer Center at Medical University of South Carolina *Recruiting*
Charleston, South Carolina, 29425-0721
United States
Recruiting Julio Barredo 803-792-2957
Huntsman Cancer Institute *Recruiting*
Salt Lake City, Utah, 84112
United States
Recruiting Carol Bruggers 801-585-0303
University of Texas Health Science Center at San Antonio *Recruiting*
San Antonio, Texas, 78207
United States
Recruiting Paul Thomas 210-704-3405
University Hospital at State University of New York - Upstate Medical University *Recruiting*
Syracuse, New York, 13210
United States
Recruiting Ronald Dubowy 315-464-5294
University of Mississippi Medical Center *Recruiting*
Jackson, Mississippi, 39216-4505
United States
Recruiting Dale Pullen 601-984-5220
CCOP - St. Vincent Hospital Cancer Center, Green Bay *Recruiting*
Green Bay, Wisconsin, 54301
United States
Recruiting Thomas Saphner 920-432-5134
Baylor College of Medicine *Recruiting*
Houston, Texas, 77030
United States
Recruiting C. Steuber 713-770-4200
Miami Children's Hospital *Recruiting*
Miami, Florida, 33155-4069
United States
Recruiting Enrique Escalon 305-662-8360
Women and Children's Hospital of Buffalo *Recruiting*
Buffalo, New York, 14222
United States
Recruiting Patricia Duffner 716-878-7848
Children's Hospital of New Orleans *Recruiting*
New Orleans, Louisiana, 70118
United States
Recruiting Rajasekharan Warrier 504-568-4561
CCOP - Marshfield Clinic Research Foundation *Recruiting*
Marshfield, Wisconsin, 54449
United States
Recruiting Tarit Banerjee 715-387-5134
Cancer Center at Hackensack University Medical Center *Recruiting*
Hackensack, New Jersey, 07601
United States
Recruiting Michael Harris 201-996-5437
Duke Comprehensive Cancer Center *Recruiting*
Durham, North Carolina, 27710
United States
Recruiting Philip Breitfeld 919-684-3377
Children's Hospital of Michigan *Recruiting*
Detroit, Michigan, 48201
United States
Recruiting Yaddanapudi Ravindranath 313-745-5649
Women's and Children's Hospital *Recruiting*
North Adelaide, South Australia, 5006
Australia
Recruiting Maria Kirby 61-8-8161-7411
Additional Information:
Study ID Numbers: CDR0000069100; NCI-P01-0198,COG-ACCL0131
Study Start Date:
Record last reviewed: August 2003
Additional information available at: clinicaltrials.gov
Clinicaltrials.gov Reference link: NCT00028509
Other Long-Term Effects Secondary To Cancer Therapy In Children Studies:
1. Genetic Study of Late-Occurring Complications in Childhood Cancer Survivors
2. Study of Lung Function in Children Who Have Undergone Bone Marrow Transplantation
3. Brain Function in Children Previously Treated on Clinical Trials POG-9605 and POG-9201
4. Health-Related Outcomes in Patients Who Were Previously Treated for Rhabdomyosarcoma
Related Studies:
Other long-term effects secondary to cancer therapy in children Clinical Trials
Other Texas Clinical Trials
Other San Antonio Clinical Trials
Brain Function in Children Previously Treated on Clinical Trials POG-9605 and POG-9201
|
|
|
|
|
|
|
|
