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Body Water Content in Cyanotic Congenital Heart Disease



Body Water Content in Cyanotic Congenital Heart Disease

For Condition: Heart Defects, Congenital
Status: Completed
Sponsor(s): National Center for Research Resources (NCRR) ,
Synopsis: Adults with cyanotic congenital heart disease have elevated levels of plasma proatrial natruretic peptide (proANP) which most likely results in chronic dehydration, leading to reduced oxygen transport to tissues and shortness of breath with activity. The purpose of this study is to characterize adults with cyanotic congenital heart defects with respect to their body composition (water and fat-free mass) and resting metabolic rates. The study consists of several measures of how much body water, fat and lean tissue a subject has, and measures the number of calories the subject's body uses at rest. Adult subjects with cyanotic congenital heart disease will be recruited along with healthy noncyanotic control subjects matched for age, gender, and body weight.
Details:
Eligibility:
Study Type:
  Observational, Natural History, Case Control
Minimum Age/Maximum Age: 17 Years/60 Years
Genders: Both
Protocol Entry Criteria: Inclusion Criteria: - Resting blood pressure below 140/90
Total Enrollment: 

Location and Contact Information:

University of Vermont
Burlington,  Vermont,  05401
United States
 


Additional Information:
Study ID Numbers:
  NCRR-M01RR00109-0737;  M01RR00109
Study Start Date: 
Record last reviewed: December 2003
Additional information available at: clinicaltrials.gov
Clinicaltrials.gov Reference link: NCT00000107

Other Heart Defects, Congenital Studies:
1. Liothyronine in Children with Single Ventricle Congenital Cardiac Malformations Undergoing the Fontan Procedure

2. Body Water Content in Cyanotic Congenital Heart Disease

3. Study of the Relationship Between Calcium Levels and Intact Parathyroid Hormone (iPTH) in Adults with Repaired or Palliated Conotruncal Cardiac Defects

4. Study of Triostat in Infants during Heart Surgery

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Body Water Content in Cyanotic Congenital Heart Disease

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