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Axillary Drainage Following Lymph Node Dissection in Women With Stage I or Stage II Breast Cancer Clinical Trials Resources presented on Clinical Trials Search is not meant to be a substitute for proven health advice, calls or treatment with a real medical. We aren't mDs. Always consult your doctor on Axillary Drainage Following Lymph Node Dissection in Women With Stage I or Stage II Breast Cancer conditions. Clinical Trials Search.org is a website dedicated to listing clinical research studies in human subjects. Axillary Drainage Following Lymph Node Dissection in Women With Stage I or Stage II Breast Cancer Clinical research trials and Axillary Drainage Following Lymph Node Dissection in Women With Stage I or Stage II Breast Cancer healthcare trials take place in a lot of of localities throughout the U.S.. A clinical trial or clinical study is a research project with human volunteer subjects. Clinical drug trials and pharmaceutical clinical trials typically assess the effectiveness of new does drugs. The function of the studies / projects is to figure out specific human medical questions. Clinical trials are a popular means for doctors, government agencies, and private sector corporations to find cures for all varieties of conditions, like Axillary Drainage Following Lymph Node Dissection in Women With Stage I or Stage II Breast Cancer. Axillary Drainage Following Lymph Node Dissection in Women With Stage I or Stage II Breast Cancer Clinical Trials and other clinical trials allow volunteers to access health treatment options before they are available to the masses. Many times the subjects receive professional assistance for free, and every now and again they are compensated for their time. Sometimes there is a cost for a Axillary Drainage Following Lymph Node Dissection in Women With Stage I or Stage II Breast Cancer clinical trial. Human subjects often obtain the finest healthcare possible for their Axillary Drainage Following Lymph Node Dissection in Women With Stage I or Stage II Breast Cancer condition. Hazards are a reality, nevertheless, and might include additional or frequent dr. calls, health hazards (potentially life-jeopardizing), and/or the treatment being uneffective. Trials are federally regulated with stern guidelines to protect clinical trials patients.
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Home > "A" Clinical Trials Conditions > Axillary Drainage Following Lymph Node Dissection in Women With Stage I or Stage II Breast Cancer Axillary Drainage Following Lymph Node Dissection in Women With Stage I or Stage II Breast Cancer
Axillary Drainage Following Lymph Node Dissection in Women With Stage I or Stage II Breast Cancer
For Condition: Lymphedema,stage 1 breast cancer,perioperative/postoperative complications,stage 2 breast cancer
Status: Recruiting
Sponsor(s): Royal Marsden NHS Trust ,
Synopsis: RATIONALE: The use of axillary drains may help to prevent complications following axillary lymph node dissection. PURPOSE: Randomized clinical trial to compare the effectiveness of three methods of axillary drainage following lymph node dissection in women who have stage I or stage II breast cancer.
Details: OBJECTIVES: - Compare high vacuum drainage vs low vacuum drainage vs simple tube drainage in patients undergoing axillary surgery for stage I or II breast cancer. OUTLINE: This is a randomized study. Patients undergo axillary dissection, then are randomized to one of three axillary drainage systems. - Arm I: Patients receive high vacuum drainage. - Arm II: Patients receive low vacuum drainage. - Arm III: Patients receive simple tube drainage (no vacuum). All drains are removed when daily volumes are below 30 mL or at 5 days after surgery, regardless of drain volume. Patients are followed at day 10 and at 3 months. PROJECTED ACCRUAL: A total of 200 patients will be accrued for this study.
Eligibility:
Study Type: Interventional, Treatment
Minimum Age/Maximum Age: 18 Years/
Genders: Both
Protocol Entry Criteria: DISEASE CHARACTERISTICS: - Diagnosis of resectable stage I or II breast cancer - Planned primary surgery of level II or III axillary dissection in association with one of the following: - Wide local excision (may be done through separate incision) - No breast surgery - Bilateral surgery allowed - No prior mastectomy - No immediate breast reconstruction using implants, latissimus dorsi, or rectus abdominus myocutaneous flaps at primary operation - Hormone receptor status: - Not specified PATIENT CHARACTERISTICS: Age: - 18 and over Sex: - Female Menopausal status: - Not specified Performance status: - Not specified Life expectancy: - Not specified Hematopoietic: - Not specified Hepatic: - Not specified Renal: - Not specified Other: - Not pregnant PRIOR CONCURRENT THERAPY: Biologic therapy: - Not specified Chemotherapy: - Not specified Endocrine therapy: - Not specified Radiotherapy: - No prior radiotherapy Surgery: - See Disease Characteristics - No prior axillary surgery
Total Enrollment:
Location and Contact Information:
Overall Study Official:
GeraldGui, Study Chair, Royal Marsden NHS Trust
Royal Marsden Hospital - Sutton *Recruiting*
Sutton, England, SM2 5PT
United Kingdom
Recruiting Anthony Nash 44-20-8642-6011
Royal Marsden NHS Trust - London *Recruiting*
London, England, SW3 6JJ
United Kingdom
Recruiting Gerald Gui 44-20-7808-2783
Additional Information:
Study ID Numbers: CDR0000067713; EU-20004,RMNHS-1489
Study Start Date:
Record last reviewed: September 2000
Additional information available at: clinicaltrials.gov
Clinicaltrials.gov Reference link: NCT00005600
Other Lymphedema Studies:
1. Epoetin Alfa in Treating Chemotherapy-Related Anemia in Women With Stage I, Stage II, or Stage III Breast Cancer
2. Radiation Therapy Following Surgery in Treating Women With Early-Stage Invasive Breast Cancer
3. Microwave Thermotherapy in Treating Women With Stage I or Stage II Breast Cancer
4. Soy Isoflavone Compared With No Treatment Before Surgery in Treating Patients With Breast Cancer
5. Epirubicin Combined With Docetaxel Before Surgery in Treating Women With Early Breast Cancer
Related Studies:
Other Lymphedema Clinical Trials
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Axillary Drainage Following Lymph Node Dissection in Women With Stage I or Stage II Breast Cancer
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