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Atazanavir Versus Lopinavir/Ritonavir (LPV/RTV) in Patients Who Have Not Had Success with Protease Inhibitor-Containing HAART Regimen(s) Clinical Trials Data presented on Clinical Trials Search is not meant to be a substitute for qualified medical advice, visits or professional assistance with a genuine dr.. We are not doctors. Always consult your mD about Atazanavir Versus Lopinavir/Ritonavir (LPV/RTV) in Patients Who Have Not Had Success with Protease Inhibitor-Containing HAART Regimen(s) conditions. Clinical Trials Search.org is a site devoted to listing clinical research studies in human subjects. Atazanavir Versus Lopinavir/Ritonavir (LPV/RTV) in Patients Who Have Not Had Success with Protease Inhibitor-Containing HAART Regimen(s) Clinical research trials and Atazanavir Versus Lopinavir/Ritonavir (LPV/RTV) in Patients Who Have Not Had Success with Protease Inhibitor-Containing HAART Regimen(s) medical trials take place in many of places throughout the U.S.A.. A clinical trial or clinical study is a research project with human volunteer subjects. Clinical drug trials and pharmaceutical clinical trials usually evaluate the effectiveness of new does drugs. The purpose of the studies / projects is to solve specific human healthcare questions. Clinical trials are a popular way for mDs, government agencies, and private sector companies to find cures for all varieties of conditions, like Atazanavir Versus Lopinavir/Ritonavir (LPV/RTV) in Patients Who Have Not Had Success with Protease Inhibitor-Containing HAART Regimen(s). Atazanavir Versus Lopinavir/Ritonavir (LPV/RTV) in Patients Who Have Not Had Success with Protease Inhibitor-Containing HAART Regimen(s) Clinical Trials and other clinical trials allow for volunteers to have health treatment options before they are available to the masses. Many times the human subjects acquire professional assistance for free of charge, and sometimes they are compensated for their time. Occasionally there is a cost for a Atazanavir Versus Lopinavir/Ritonavir (LPV/RTV) in Patients Who Have Not Had Success with Protease Inhibitor-Containing HAART Regimen(s) clinical trial. Test subjects typically obtain the finest healthcare available for their Atazanavir Versus Lopinavir/Ritonavir (LPV/RTV) in Patients Who Have Not Had Success with Protease Inhibitor-Containing HAART Regimen(s) condition. Dangers are a reality, nevertheless, and might include additional or frequent doctor trips, medical dangers (possibly life-jeopardising), and/or the treatment being ineffectual. Trials are federally regulated with strict guidelines to protect clinical trials patients.

Home > "A" Clinical Trials Conditions > Atazanavir Versus Lopinavir/Ritonavir (LPV/RTV) in Patients Who Have Not Had Success with Protease Inhibitor-Containing HAART Regimen(s)

Atazanavir Versus Lopinavir/Ritonavir (LPV/RTV) in Patients Who Have Not Had Success with Protease Inhibitor-Containing HAART Regimen(s)



Atazanavir Versus Lopinavir/Ritonavir (LPV/RTV) in Patients Who Have Not Had Success with Protease Inhibitor-Containing HAART Regimen(s)

For Condition: HIV Infections
Status: No longer recruiting
Sponsor(s): Bristol-Myers Squibb ,
Synopsis: This study will compare 2 treatments in the way they affect cholesterol levels and the amount of HIV in the blood.
Details: The study is designed to determine the metabolic changes, antiviral activity, safety, and tolerability of atazanavir as compared to LPV/RTV, each in combination with 2 nucleosides, over the initial 24 weeks, with a final analysis at 48 weeks.
Eligibility:
Study Type:
  Interventional, Treatment, Open Label, Safety Study
Minimum Age/Maximum Age: 16 Years/
Genders: Both
Protocol Entry Criteria: Inclusion Criteria Patients may be eligible for this study if they: - Are receiving a PI-containing highly active antiretroviral therapy (HAART) for at least 12 weeks. - Have a viral load of 1,000 or more copies/ml within 4 weeks of screening and within 4 weeks prior to randomization. - Have 2 CD4 cell counts of 50 or more cells/mm3 at least 96 hours apart and within 4 weeks before randomization. - Are at least 16 years old. - Have a documented virologic response to at least 1 HAART regimen. - Have phenotypic sensitivity to at least 2 of the following: ddl, d4T, ZDV, 3TC, ABC. - Have phenotypic sensitivity to atazanavir and LPV/RTV. - Use effective barrier methods of birth control. - Will be available for 48 weeks. Exclusion Criteria Patients will not be eligible for this study if they: - Have taken 2 or more PIs and had virologic failure. - Have taken atazanavir or LPV/RTV. - Have an HIV-related infection (within 30 days) or any medical condition requiring treatment at the time of enrollment. - Have had acute hepatitis in the 30 days prior to study entry. - Have received certain drugs within 3 months of study start or expect to need them at time of enrollment. - Abuse alcohol or drugs in a way that would interfere with the study. - Have very bad diarrhea within 30 days prior to study entry. - Are pregnant or breast-feeding. - Have a history of hemophilia. - Use lipid-lowering drugs (within the previous 30 days). - Have cardiomyopathy or symptoms of other heart disease. - Cannot take medicine by mouth. - Have any other condition that would interfere with the study. - Have pancreatitis, if choosing ddI as part of NRTI pair. - Have bilateral peripheral neuropathy at time of screening, if choosing ddI or or d4T as part of the NRTI pair.
Total Enrollment: 

Location and Contact Information:

Univ Medical Center Utrecht
CX Utrecht,  , 
Netherlands
 

Phoenix Body Positive
Phoenix,  Arizona,  85006
United States
 

Saint Francis Mem Hosp / HIV Care Unit
San Francisco,  California,  94109
United States
 

Infectious Disease of Indiana
Indianapolis,  Indiana,  46218
United States
 

CHU Saint Pierre
Brussels,  , 
Belgium
 

East Bay AIDS Ctr
Berkeley,  California,  94705
United States
 

Hosp Sotero de Rio
Santiago,  , 
Chile
 

Hospital Germans Trias I Pujol
Barcelona,  , 
Spain
 

North Texas Center for AIDS & Clinical Research
Dallas,  Texas,  75208
United States
 

Harbor UCLA Med Ctr
Torrance,  California,  90502
United States
 

Univ of Massachusetts
Worcester,  Massachusetts,  01655
United States
 

North Shore Univ Hosp
Manhasset,  New York,  11030
United States
 

Ospedale degli Infermi
Rimini,  , 
Italy
 

North Jersey Community Research Initiative
Newark,  New Jersey,  071032842
United States
 

Hopital Cochin - Port Royal
Paris,  , 
France
 

Cooper Green Hosp
Birmingham,  Alabama,  35233
United States
 

Aurora Hospital
Unknown,  , 
Finland
 

Ospedale S Raffaele
Milano,  , 
Italy
 

Hosp de Basurto / Enfermedades Infecciosas
Bilboa,  , 
Spain
 

Royal Liverpool Univ Hosp
Liverpool,  , 
United Kingdom
 

Univ of Hawaii
Honolulu,  Hawaii,  96816
United States
 

Community Research Initiative
Brookline,  Massachusetts,  02445
United States
 

Dr Roger P Leblanc
Montreal,  Quebec, 
Canada
 

Southampton Healthcare Inc
St. Louis,  Missouri,  63139
United States
 

Florida ID Group
Orlando,  Florida,  32801
United States
 

Domaine Universitaire Du SART-TILMAN
LIEGE,  , 
Belgium
 

Prahran Market Clinic
South Yarra,  , 
Australia
 

Hosp Nacional Cayetano Heredia
Lima,  , 
Peru
 

Hospital de Clinicas da Universidade Federal do Parana
Curitiba,  , 
Brazil
 

Hospital 1 ro de Octubre
Mexico City,  , 
Mexico
 

Inst of Tropical Medicine
Antwerpe,  , 
Belgium
 

Fundacion Huesped
Buenos Aires,  , 
Argentina
 

Taylors Square Clinic
Sydney,  , 
Australia
 

Hospital Nossa Senhora da Conceicao-GCH
Porto Alegre,  , 
Brazil
 

Erie County Med Ctr
Buffalo,  New York,  14215
United States
 

Oregon Health Sciences Univ
Portland,  Oregon,  97201
United States
 

San Francisco Veterans Administration Med Ctr
San Francisco,  California,  94121
United States
 

Infectious Disease Specialists of Atlanta
Decatur,  Georgia,  30033
United States
 

Montreal Gen Hosp / Div of Clin Immuno and Allergy
Montreal,  Quebec, 
Canada
 

Houston Clinical Research Network
Houston,  Texas,  77006
United States
 

Hospital General
Mexico City,  , 
Mexico
 

San Cristobal Hosp
Coto Laurel, Ponce,  ,  00780
Puerto Rico
 

Sky Blue
Boise,  Idaho,  83704
United States
 

Hospital Italiano
Buenos Aires,  , 
Argentina
 

Clinical Research Puerto Rico Inc
San Juan,  ,  009091711
Puerto Rico
 

Whittal Street Clinic
Birmingham,  , 
United Kingdom
 

Hosp Ramon y Cajal
Madris,  , 
Spain
 

Elida Pallone MD
Buenos Aires,  , 
Argentina
 

Hosp Nuestra Senora de Covadonga
Oviedo,  , 
Spain
 

Alfred Hosp
Prahan,  , 
Australia
 

Hosp Reina Sofia
Cordoba,  , 
Spain
 

Hosp Virgen Del Rocio
Sevilla,  , 
Spain
 

Cat All Immun Clin
Roma,  , 
Italy
 

Ospedale Amedeo di Savoia
Torino,  , 
Italy
 

Community Health Care
Ft. Lauderdale,  Florida,  33306
United States
 

Clinique Medicale du Quartier Latin
Montreal,  Quebec, 
Canada
 

Larry Bush
Atlantis,  Florida,  33462
United States
 

Infectious Diseases Associates of Houston
Houston,  Texas,  77030
United States
 

Beacon Clinic / Boulder Community Hosp
Boulder,  Colorado,  80304
United States
 

Instituto de Infectologia Emilio Ribas
Sao Paulo,  , 
Brazil
 

VAMC New Jersey Healthcare System
East Orange,  New Jersey,  07018
United States
 

Hopital Gustave Dron
Tourcoing,  , 
France
 

Jemsek Clinic
Huntersville,  North Carolina,  28078
United States
 

IDC Research Initiative
Altamonte Springs,  Florida,  32701
United States
 

South Beach Medical Associates
Miami,  Florida,  33160
United States
 

Nicholas Bellos
Dallas,  Texas,  75246
United States
 

Ospedale Luigi Sacco Cargnel
Milano,  , 
Italy
 

Services des Maladies Infectieuses
Paris Cedex 12,  , 
France
 

Ospedale S Orsola
Bologna,  , 
Italy
 

Univ of Kentucky Med Ctr
Lexington,  Kentucky,  40536
United States
 

University Hospital Gent
Gent,  , 
Belgium
 

Fundacion Arriaran
Santiago,  , 
Chile
 

Univ of Kansas School of Medicine
Wichita,  Kansas,  672143124
United States
 

Immunoligia Universita Cagliari
Cagliari,  , 
Italy
 

Toronto Hosp
Toronto,  Ontario, 
Canada
 

Hospital Regional
Mexico City,  , 
Mexico
 

CHU De Bicetre
Paris,  , 
France
 

Kaiser Foundation Hospital
San Francisco,  California,  94118
United States
 

CAICI
Rosario Santa Fe,  , 
Argentina
 

Hosp Clinic
Barcelona,  , 
Spain
 

Reparto di Malattie Infettive
Corso Svizzera,  , 
Italy
 

Mark Watkins
Philadelphia,  Pennsylvania,  19107
United States
 

Hosp Guillermo Almenara-Medicina 1
Lima,  , 
Peru
 

Univ of South Carolina School of Medicine
Columbia,  South Carolina,  29203
United States
 

Klinicka Chorobzkaznych AM
Unknown,  , 
Poland
 

Department of Infection & Tropical Medicine
Unknown,  , 
United Kingdom
 

Cliniques Universitaires Saint Luc
BRUXELLES,  , 
Belgium
 

Steven Zell
Reno,  Nevada,  89502
United States
 

Instituto Nacional de la Nutricion
Mexico City,  , 
Mexico
 

Research & Education Group
Portland,  Oregon,  97209
United States
 

Hosp Carlos III
Madrid,  , 
Spain
 

Claudia Rodriguez MD
Buenos Aires,  , 
Argentina
 

Hopital Hotel Dieu de Lyon
Lyon,  , 
France
 

Albany Med College
Albany,  New York,  12208
United States
 

Community Health Network
Rochester,  New York,  14620
United States
 

Ospedale Amedeo de Savoia
Torino,  , 
Italy
 

Saint Vincent's Hosp Med Centre
Sydney,  , 
Australia
 


Additional Information:
Study ID Numbers:
  302D;  AI424-043
Study Start Date: February 2001
Record last reviewed: February 2004
Additional information available at: clinicaltrials.gov
Clinicaltrials.gov Reference link: NCT00028301

Other Hiv Infections Studies:
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