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Assessment of Potential Interactions Between Intravenous Methamphetamine and Oral Selegiline - 1



Assessment of Potential Interactions Between Intravenous Methamphetamine and Oral Selegiline - 1

For Condition: Substance-Related Disorders,Infusions, Intravenous,Substance Abuse, Intravenous
Status: No longer recruiting
Sponsor(s): National Institute on Drug Abuse (NIDA) ,
Synopsis: An assessment of potential interactions between intravenous methamphetamine and oral selegiline.
Details: To determine the safety of the selegiline concurrent with d-methamphetamine challenges of 15mg & 30mg i.v. with the focus being on cardiovascular responses (HR,BP) to the i.v. methamphetamine challenges. This is a randomized, single-blind, placebo-controlled, two-arm study design to evaluate the safety of selegiline treatment, compared to placebo treatment, concurrent with i.v. methamphetamine challenges.
Eligibility:
Study Type:
  Interventional, Treatment, Randomized, Single Blind, Placebo Control
Minimum Age/Maximum Age: 18 Years/45 Years
Genders: Both
Protocol Entry Criteria: Inclusion Criteria: Volunteers who meet DSM-4 criteria for methamphetamine abuse or dependence; non-treatment seeking individuals; between 18-45 yrs of age; be able to verbalize understanding of consent form; provide written informed consent Exclusion Criteria: Additional criteria available during screening at the site
Total Enrollment: 16

Location and Contact Information:

Overall Study Official:
ThomasNewton,  Principal Investigator,  University of California, Los Angeles

UCLA Integrated Substance Abuse Program
Los Angeles,  California,  90024
United States
 


Additional Information:
Study ID Numbers:
  NIDA-CTO-0004-1; 
Study Start Date: September 2001
Record last reviewed: November 2003
Additional information available at: clinicaltrials.gov
Clinicaltrials.gov Reference link: NCT00033072

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