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Anemia in Patients with a Non-Myeloid Malignancy Clinical Trials Info presented on Clinical Trials Search isn't intended to be a substitute for certified health advice, travels to or treatment by using a genuine physician. We are not physicians. Always consult your dr. on Anemia in Patients with a Non-Myeloid Malignancy conditions. Clinical Trials Search.org is a site committed to listing clinical research studies in human subjects. Anemia in Patients with a Non-Myeloid Malignancy Clinical research trials and Anemia in Patients with a Non-Myeloid Malignancy health trials occur in hundreds of cities throughout the U.S.A.. A clinical trial or clinical study is a research project with human volunteer subjects. Clinical drug trials and pharmaceutical clinical trials typically assess the effectivity of new drugs. The propose of the studies / undertakings is to resolve certain human health questions. Clinical trials are a popular means for physicians, government agencies, and private sector companies to locate treatments for all sorts of conditions, including Anemia in Patients with a Non-Myeloid Malignancy. Anemia in Patients with a Non-Myeloid Malignancy Clinical Trials and other clinical trials permit volunteers to acquire medical treatment choices before they are available to the masses. Some times the test subjects obtain professional assistance for free, and every now and again they are compensated for their time. Sometimes there is a cost for a Anemia in Patients with a Non-Myeloid Malignancy clinical trial. Participants oftentimes recieve the most expert healthcare available for their Anemia in Patients with a Non-Myeloid Malignancy condition. Hazards are a reality, however, and can include extra or frequent physician visits, health risks (potentially life-endangering), and/or the treatment being uneffective. Trials are federally governed with rigorous guidelines to protect clinical trials subjects.

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Anemia in Patients with a Non-Myeloid Malignancy



Anemia in Patients with a Non-Myeloid Malignancy

For Condition: Neoplasms,Anemia
Status: No longer recruiting
Sponsor(s): Amgen ,
Synopsis: Chemotherapy can often cause anemia in patients with cancer. Anemia is a low number of red blood cells. The symptoms of anemia may include fatigue, dizziness, headache, chest pain, and shortness of breath. Erythropoietin is a hormone made by the kidneys that signals the bone marrow to produce more red blood cells. Recombinant human erythropoeitin has been produced in the laboratory and has the same effect as the hormone produced by the body. Use of recombinant human erythropoeitin allows the body to produce more red blood cells, possibly eliminating or decreasing your symptoms and the need for a red blood cell transfusion. Recombinant human erythropoeitin is FDA approved to treat anemia in cancer patients receiving chemotherapy. This clinical study is investigating the effectiveness of darbepoetin alfa for the treatment of anemia in patients with non-myeloid malignanices who are receiving multicycle chemotherapy. Darbepoetin alfa is a recombinant erythropoeitic protein that stimulates the production of red blood cells. This medication has not been approved to treat cancer patients with anemia, however it has been approved by the FDA to treat chronic renal failure patients with anemia.
Details:
Eligibility:
Study Type:
  Interventional, Treatment
Minimum Age/Maximum Age: 18 Years/
Genders: Both
Protocol Entry Criteria: - Men or women of legal age, diagnosed with a non-myeloid malignancy and scheduled to receive a minimum of an additional 12 weeks of cytotoxic chemotherapy from the time of first dose of study drug. Screening hemoglobin concentration less than or equal to 11.0 g/dL, ECOG performance status of 0 to 2 (inclusive). - Subjects with a history of seizure disorder, primary hematologic disorder that could cause anemia, unstable or uncontrolled disease/condition related to or affecting cardiac function, clinical evidence of chronic infection/inflammatory disease, positive test for HIV infection, or previously confirmed neutralizing antibodies to rHuEPO will be excluded from the study.
Total Enrollment: 1200

Location and Contact Information:

Research Center
Casper,  Wyoming, 
United States
 

Research Center
Los Angeles,  California, 
United States
 

Research Center
Hot Springs,  Arkansas, 
United States
 

Research Center
Huntington,  New York, 
United States
 

Research Center
Orange City,  Florida, 
United States
 

Research Center
Bronx,  New York, 
United States
 

Research Center
Toledo,  Ohio, 
United States
 

Research Center
Fountain Valley,  California, 
United States
 

Research Center
Columbia,  South Carolina, 
United States
 

Research Center
Bismark,  North Dakota, 
United States
 

Research Center
Bay City,  Michigan, 
United States
 

Research Center
Macon,  Georgia, 
United States
 

Research Center
Long Beach,  California, 
United States
 

Research Center
Chicago,  Illinois, 
United States
 

Research Center
Fergus Falls,  Minnesota, 
United States
 

Research Center
Birmingham,  Alabama, 
United States
 

Research Center
New Haven,  Connecticut, 
United States
 

Research Center
Jackson,  Mississippi, 
United States
 

Research Center
Minot,  North Dakota, 
United States
 

Research Center
Tucson,  Arizona, 
United States
 

Research Center
Boynton Beach,  Florida, 
United States
 

Research Center
Bristol,  Tennessee, 
United States
 

Research Center
Detroit,  Michigan, 
United States
 


Additional Information:
Study ID Numbers:
  20010101; 
Study Start Date: 
Record last reviewed: September 2003
Additional information available at: clinicaltrials.gov
Clinicaltrials.gov Reference link: NCT00038064

Other Anemia Studies:
1. Ro 50-3821 in Treating Anemia in Patients Receiving Antineoplastic Therapy for Stage IIIB or Stage IV Non-Small Cell Lung Cancer

2. Treatment of T-Large Granular Lymphocyte (T-LGL) Lymphoproliferative Disorders with Cyclosporine

3. Epoetin Alfa in Treating Chemotherapy-Related Anemia in Women With Stage I, Stage II, or Stage III Breast Cancer

4. Darbepoetin alfa in Treating Anemia in Patients With Cancer Who Are Receiving Chemotherapy

5. Radiation Therapy and Cisplatin With or Without Epoetin Alfa in Treating Patients With Cervical Cancer and Anemia

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Anemia in Patients with a Non-Myeloid Malignancy

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