Search Clinical Trials
By Condition
By Location (USA)
By Location (Other)
By Sponsor
Resources
Privacy Policy
About Us
Disclaimer
Aminocamptothecin in Treating Patients With Recurrent or Refractory Ovarian Epithelial Cancer or Primary Cancer of the Peritoneum Clinical Trials Facts presented on Clinical Trials Search isn't designed to be a substitute for proven healthcare advice, calls or treatment by using a genuine medical doctor. We aren't mDs. Always confer with your doctor on Aminocamptothecin in Treating Patients With Recurrent or Refractory Ovarian Epithelial Cancer or Primary Cancer of the Peritoneum conditions. Clinical Trials Search.org is a website devoted to listing clinical research studies in human subjects. Aminocamptothecin in Treating Patients With Recurrent or Refractory Ovarian Epithelial Cancer or Primary Cancer of the Peritoneum Clinical research trials and Aminocamptothecin in Treating Patients With Recurrent or Refractory Ovarian Epithelial Cancer or Primary Cancer of the Peritoneum healthcare trials occur in a lot of of places across the United States. A clinical trial or clinical study is a research project with human volunteer subjects. Clinical drug trials and pharmaceutical clinical trials generally assess the effectivity of new does drugs. The role of the studies / undertakings is to solve specific human healthcare questions. Clinical trials are a popular way for doctors, government agencies, and private sector companies to find treatments for all kinds of conditions, including Aminocamptothecin in Treating Patients With Recurrent or Refractory Ovarian Epithelial Cancer or Primary Cancer of the Peritoneum. Aminocamptothecin in Treating Patients With Recurrent or Refractory Ovarian Epithelial Cancer or Primary Cancer of the Peritoneum Clinical Trials and other clinical trials allow for volunteers to access health treatment choices before they are available to the general public. Many times the test subjects get treatment for without cost, and sometimes they are compensated for their time. Occasionally there is a cost for a Aminocamptothecin in Treating Patients With Recurrent or Refractory Ovarian Epithelial Cancer or Primary Cancer of the Peritoneum clinical trial. Test subjects typically receive the most effective healthcare possible for their Aminocamptothecin in Treating Patients With Recurrent or Refractory Ovarian Epithelial Cancer or Primary Cancer of the Peritoneum condition. Risks are a reality, nonetheless, and could include extra or frequent dr. calls, health hazards (perhaps life-jeopardizing), and/or the treatment being ineffective. Trials are federally regulated with rigid guidelines to protect clinical trials subjects.

Home > "A" Clinical Trials Conditions > Aminocamptothecin in Treating Patients With Recurrent or Refractory Ovarian Epithelial Cancer or Primary Cancer of the Peritoneum

Aminocamptothecin in Treating Patients With Recurrent or Refractory Ovarian Epithelial Cancer or Primary Cancer of the Peritoneum



Aminocamptothecin in Treating Patients With Recurrent or Refractory Ovarian Epithelial Cancer or Primary Cancer of the Peritoneum

For Condition: recurrent ovarian epithelial cancer,peritoneal cavity cancer
Status: No longer recruiting
Sponsor(s): National Cancer Institute (NCI) , Gynecologic Oncology Group
Synopsis: RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. PURPOSE: Phase II trial to study the effectiveness of aminocamptothecin in treating patients with recurrent or refractory ovarian epithelial cancer or primary cancer of the peritoneum.
Details: OBJECTIVES: I. Estimate the antitumor activity of aminocamptothecin colloidal dispersion in patients with platinum-resistant recurrent or refractory ovarian cancer or primary peritoneal carcinoma who have failed on higher priority treatment protocols. II. Determine the nature and degree of toxicity of aminocamptothecin colloidal dispersion in this patient population. PROTOCOL OUTLINE: Patients receive aminocamptothecin colloidal dispersion IV over 120 hours weekly for two of every three weeks. Courses are repeated every 21 days in the absence of disease progression or unacceptable toxicity. Patients are followed every 3 months for 2 years, then every 6 months for 3 years. PROJECTED ACCRUAL: Approximately 23-56 patients will be accrued for this study within 5-12 months.
Eligibility:
Study Type:
  Interventional, Treatment
Minimum Age/Maximum Age: 13 Years/
Genders: 
Protocol Entry Criteria: PROTOCOL ENTRY CRITERIA: --Disease Characteristics-- - Histologically confirmed recurrent or persistent ovarian epithelial cancer or primary peritoneal carcinoma; Progressive disease on platinum-based treatment alone or in combination; Two prior treatment regimens allowed only if other regimen was paclitaxel OR recurrence within 6 months of chemotherapy - Measurable disease - Not eligible for a higher priority GOG protocol --Prior/Concurrent Therapy-- - Biologic therapy: At least 4 weeks since prior biologic therapy - Chemotherapy: See Disease Characteristics; At least 4 weeks since prior chemotherapy and recovered; No prior treatment with aminocamptothecin - Endocrine therapy: At least 4 weeks since prior endocrine therapy - Radiotherapy: At least 4 weeks since prior radiotherapy and recovered; No prior radiotherapy to site(s) of measurable disease used on this trial; No prior radiotherapy to more than 25% of marrow-bearing areas - Surgery: At least 4 weeks since prior surgery --Patient Characteristics-- - Age: 13 and over - Performance status: GOG 0-2 - Life expectancy: Not specified - Hematopoietic: WBC at least 3,000/mm3; Platelet count at least 100,000/mm3; Granulocyte count at least 1,500/mm3 - Hepatic: Bilirubin no greater than 1.5 mg/dL; SGOT/SGPT no greater than 2.5 times upper limit of normal (ULN); Alkaline phosphatase no greater than 2.5 times ULN - Renal: Creatinine no greater than 1.5 mg/dL - Other: No significant infection; Not pregnant; Fertile patients must use effective contraception; At least 5 years since prior malignancy; no prior chemotherapy or radiotherapy for that malignancy; No concurrent malignancy other than non-melanoma skin cancer
Total Enrollment: 

Location and Contact Information:

Overall Study Official:
DavidMiller,  Study Chair,  Gynecologic Oncology Group

University of Rochester Cancer Center
Rochester,  New York,  14642
United States
 

Women's Cancer Center
Palo Alto,  California,  94304
United States
 

University of Colorado Cancer Center
Denver,  Colorado,  80262
United States
 

State University of New York Health Sciences Center - Stony Brook
Stony Brook,  New York,  11790-7775
United States
 

University of Washington Medical Center
Seattle,  Washington,  98195-6043
United States
 

CCOP - Montana Cancer Consortium
Billings,  Montana,  59101
United States
 

CCOP - Baptist Cancer Institute
Memphis,  Tennessee,  38117
United States
 

State University of New York Health Science Center at Brooklyn
Brooklyn,  New York,  11203
United States
 

CCOP - Atlanta Regional
Atlanta,  Georgia,  30342-1701
United States
 

H. Lee Moffitt Cancer Center and Research Institute
Tampa,  Florida,  33612
United States
 

Brookview Research, Inc.
Nashville,  Tennessee,  37203
United States
 

Comprehensive Cancer Center of Wake Forest University Baptist Medical Center
Winston Salem,  North Carolina,  27157-1082
United States
 

Chao Family Comprehensive Cancer Center
Orange,  California,  92868
United States
 

Medical University of South Carolina
Charleston,  South Carolina,  29425-0721
United States
 

CCOP - Kansas City
Kansas City,  Missouri,  64131
United States
 

CCOP - Sooner State
Tulsa,  Oklahoma,  74136
United States
 

Milton S. Hershey Medical Center
Hershey,  Pennsylvania,  17033
United States
 

Cancer Center of Albany Medical Center
Albany,  New York,  12208
United States
 

USC/Norris Comprehensive Cancer Center
Los Angeles,  California,  90033-0800
United States
 

Barbara Ann Karmanos Cancer Institute
Detroit,  Michigan,  48201
United States
 

University of Oklahoma College of Medicine
Oklahoma City,  Oklahoma,  73190
United States
 

University of Pennsylvania Cancer Center
Philadelphia,  Pennsylvania,  19104
United States
 

Vincent T. Lombardi Cancer Research Center, Georgetown University
Washington D.C.,  District of Columbia,  20007
United States
 

Emory University Hospital - Atlanta
Atlanta,  Georgia,  30322
United States
 

Radiation Oncology Branch
Bethesda,  Maryland,  20892
United States
 

Indiana University Cancer Center
Indianapolis,  Indiana,  46202-5265
United States
 

University of Iowa Hospitals and Clinics
Iowa City,  Iowa,  52242
United States
 

Fox Chase Cancer Center
Philadelphia,  Pennsylvania,  19111
United States
 

CCOP - Missouri Valley Cancer Consortium
Omaha,  Nebraska,  68131
United States
 

Rush-Presbyterian-St. Luke's Medical Center
Chicago,  Illinois,  60612
United States
 

University of Texas - MD Anderson Cancer Center
Houston,  Texas,  77030
United States
 

Cooper Hospital/University Medical Center
Camden,  New Jersey,  08103
United States
 

Walter Reed Army Medical Center
Washington D.C.,  District of Columbia,  20307-5000
United States
 

University of Chicago Cancer Research Center
Chicago,  Illinois,  60637
United States
 

Memorial Sloan-Kettering Cancer Center
New York City,  New York,  10021
United States
 

Abington Memorial Hospital
Abington,  Pennsylvania,  19001
United States
 

Lineberger Comprehensive Cancer Center, UNC
Chapel Hill,  North Carolina,  27599-7295
United States
 

Keesler Medical Center - Keesler AFB
Keesler AFB,  Mississippi,  39534-2576
United States
 

Washington University School of Medicine
St. Louis,  Missouri,  63110
United States
 

Barrett Cancer Center, The University Hospital
Cincinnati,  Ohio,  45219
United States
 

Medicine Branch
Bethesda,  Maryland,  20892
United States
 

Kimmel Cancer Center of Thomas Jefferson University - Philadelphia
Philadelphia,  Pennsylvania,  19107
United States
 

CCOP - Upstate Carolina
Spartanburg,  South Carolina,  29303
United States
 

CCOP - Evanston
Evanston,  Illinois,  60201
United States
 

North Shore University Hospital
Manhasset,  New York,  11030
United States
 

Ireland Cancer Center
Cleveland,  Ohio,  44106-5065
United States
 

Cleveland Clinic Cancer Center
Cleveland,  Ohio,  44195
United States
 

University of Minnesota Cancer Center
Minneapolis,  Minnesota,  55455
United States
 

Duke Comprehensive Cancer Center
Durham,  North Carolina,  27710
United States
 

Arthur G. James Cancer Hospital - Ohio State University
Columbus,  Ohio,  43210
United States
 

University of Mississippi Medical Center
Jackson,  Mississippi,  39216-4505
United States
 

Tacoma General Hospital
Tacoma,  Washington,  98405
United States
 

CCOP - Greater Phoenix
Phoenix,  Arizona,  85006-2726
United States
 

MBCCOP - Hawaii
Honolulu,  Hawaii,  96813
United States
 

Jonsson Comprehensive Cancer Center, UCLA
Los Angeles,  California,  90095-1781
United States
 

Simmons Cancer Center - Dallas
Dallas,  Texas,  75235-9154
United States
 

Johns Hopkins Oncology Center
Baltimore,  Maryland,  21231
United States
 

CCOP - Ann Arbor Regional
Ann Arbor,  Michigan,  48106
United States
 

University of Massachusetts Memorial Medical Center
Worcester,  Massachusetts,  01655
United States
 

CCOP - Columbia River Program
Portland,  Oregon,  97213
United States
 

University of Alabama Comprehensive Cancer Center
Birmingham,  Alabama,  35294
United States
 

CCOP - Central Illinois
Decatur,  Illinois,  62526
United States
 

Albert B. Chandler Medical Center, University of Kentucky
Lexington,  Kentucky,  40536-0084
United States
 

Tom Baker Cancer Center - Calgary
Calgary,  Alberta,  T2N 4N2
Canada
 

CCOP - Southern Nevada Cancer Research Foundation
Las Vegas,  Nevada,  89106
United States
 


Additional Information:
Study ID Numbers:
  CDR0000066567;  GOG-126I
Study Start Date: June 2000
Record last reviewed: May 2004
Additional information available at: clinicaltrials.gov
Clinicaltrials.gov Reference link: NCT00003523

Other Recurrent Ovarian Epithelial Cancer Studies:
1. CT-2103 in Treating Patients With Recurrent Ovarian Epithelial or Fallopian Tube Cancer or Primary Peritoneal Cancer

2. Topotecan Plus Etoposide in Treating Patients With Recurrent Ovarian, Peritoneal, or Fallopian Tube Cancer

3. Paclitaxel in Treating Patients With Advanced Ovarian, Fallopian Tube, or Primary Peritoneal Cancer in Remission

4. Irinotecan in Treating Patients With Refractory Ovarian Epithelial, Primary Peritoneal, or Fallopian Tube Cancer

5. Gemcitabine With or Without cBR96-Doxorubicin Immunoconjugate (SGN-15) in Treating Patients With Recurrent or Persistent Ovarian Epithelial Cancer

Related Studies:

Other recurrent ovarian epithelial cancer Clinical Trials
Other New York Clinical Trials
Other Manhasset Clinical Trials

Aminocamptothecin in Treating Patients With Recurrent or Refractory Ovarian Epithelial Cancer or Primary Cancer of the Peritoneum

Modify your Search

  Other recurrent ovarian epithelial cancer Clinical Trials
  Other New York Clinical Trials
  Other Manhasset Clinical Trials


Warning: include(/var/www/cgi-bin/traxis/counter.php) [function.include]: failed to open stream: No such file or directory in /home/cts/domains/clinicaltrialssearch.org/public_html/index.php on line 103

Warning: include() [function.include]: Failed opening '/var/www/cgi-bin/traxis/counter.php' for inclusion (include_path='.:/usr/local/lib/php') in /home/cts/domains/clinicaltrialssearch.org/public_html/index.php on line 103