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Alzheimer's Disease Prevention Trial



Alzheimer's Disease Prevention Trial

For Condition: Alzheimer Disease,Memory Disorders
Status: No longer recruiting
Sponsor(s): National Institute on Aging (NIA) ,
Synopsis: This is a three-year study to determine if estrogens can prevent memory loss and Alzheimer's disease in women with a family history of Alzheimer's disease.
Details: PREventing Postmenopausal memory loss and Alzheimer's with Replacement Estrogens (PREPARE) is a double-blind-placebo controlled trial to determine whether estrogen (or estrogen and progesterone) can delay the onset of memory loss or Alzheimer's Disease in elderly women with a family history of the disease.
Eligibility:
Study Type:
  Interventional, Prevention, Randomized, Double-Blind, Placebo Control
Minimum Age/Maximum Age: 65 Years/
Genders: Female
Protocol Entry Criteria: Inclusion Criteria: - Healthy women 65 or older with a family history of memory problems not currently on estrogen. Exclusion Criteria: - Significant neurological impairment - Current estrogen use - History of breast cancer
Total Enrollment: 

Location and Contact Information:

Overall Study Official:
MarySano,  Principal Investigator,  Mount Sinai Medical Center

University of Alabama
Birmingham,  Alabama,  35294
United States
 

Lee Memorial Health System
Ft. Myers,  Florida,  33901
United States
 

St. Mary's Medical Center
West Palm Beach,  Florida,  33407
United States
 

Medical University of South Carolina
North Charleston,  South Carolina,  29406
United States
 

Johns Hopkins Bayview Medical Center
Baltimore,  Maryland,  21224
United States
 

Cornell Medical Center, New York Presbyterian Medical Center
New York City,  New York, 
United States
 

New England Center for Headache
Stamford,  Connecticut,  06902-1249
United States
 

Neurology Group of Bergen County
Ridgewood,  New Jersey,  07450
United States
 

Butler Hospital, Rhode Island Hospital
Providence,  Rhode Island,  02906
United States
 

Howard University
Washington D.C.,  District of Columbia,  20060
United States
 

Mayo Clinic Jacksonville
Jacksonville,  Florida,  32225
United States
 

North Broward Medical Center
Pompano Beach,  Florida, 
United States
 

Tallahassee Memorial Health Center
Tallahassee,  Florida,  32308
United States
 

Burke Medical Research Institute
White Plains,  New York,  10605
United States
 

Columbia University
New York City,  New York,  10032
United States
 

West Florida Regional Medical Center
Pensacola,  Florida,  32514
United States
 

Eastern Virginia Medical School
Norfolk,  Virginia,  23507-1912
United States
 

University of California, Irvine
Irvine,  California,  29697-4540
United States
 

New York United Hospital Medical Center
Port Chester,  New York,  10573
United States
 

Clinical Pharmaceutical Trials
Tulsa,  Oklahoma,  74104-5428
United States
 

Duke University Medical Center
Durham,  North Carolina,  27710
United States
 

Wein Center
Miami,  Florida,  33140
United States
 


Additional Information:
Study ID Numbers:
  IA0018;  RO 1AG15922-01
Study Start Date: 
Record last reviewed: October 2003
Additional information available at: clinicaltrials.gov
Clinicaltrials.gov Reference link: NCT00000176

Other Alzheimer Disease Studies:
1. Cholesterol Lowering Agent to Slow Progression (CLASP) of Alzheimer's Disease Study

2. Multicenter Trial of Prednisone in Alzheimer's Disease

3. Brain Imaging in Alzheimer's Disease

4. Serotonergic Pharmacotherapy for Agitation of Dementia

5. Alzheimer's Disease Anti-Inflammatory Prevention Trial (ADAPT)

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