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Acupuncture for the Treatment of Hot Flashes in Breast Cancer Patients.



Acupuncture for the Treatment of Hot Flashes in Breast Cancer Patients.

For Condition: Breast Neoplasms,Hot Flashes
Status: Recruiting
Sponsor(s): National Center for Complementary and Alternative Medicine (NCCAM) ,
Synopsis: The purpose of this trial is to determine whether acupuncture reduces the incidence of hot flashes in women with breast cancer.
Details: Hot flashes are a common side effect of treatment for breast and prostate cancer. Opioids produced by the body are associated with these hot flashes. Acupuncture causes a release of endorphins that may affect opioid levels. Several studies have shown significant decreases in hot flashes following acupuncture treatment. This study will expose participants to either acupunture or placebo to determine the effectiveness of acupuncture in alleviating hot flashes in breast cancer patients. Participants in this study will be randomly assigned to receive eight sessions of either real or placebo acupunture over 4 weeks. Participants will monitor their hot flashes in a diary that will be analyzed 6, 13, and 26 weeks after the start of the study. The frequency and severity of hot flashes will be measured. At the end of 4 weeks, participants in the placebo group will be offered real acupuncture.
Eligibility:
Study Type:  Interventional, Treatment, Randomized, Double-Blind, Placebo Control, Crossover Assignment, Efficacy Study
Minimum Age/Maximum Age: /
Genders: Both
Protocol Entry Criteria: Inclusion Criteria: - Treatment for breast cancer - Average of three or more hot flashes a day - Ability to walk Exclusion Criteria: - Surgery; initiation of a new chemotherapy regimen, immunotherapy, or radiotherapy; or initiation or cessation of hormonal therapy during the study or for 3 weeks before the start of the study - Pharmacological treatment of hot flashes or use of selective serotonin reuptake inhibitors (unless the dose has been stable for 4 weeks) - Skin infections - Any acupuncture treatment within the 6 weeks prior to study entry or acupuncture given specifically for the treatment of hot flashes within 6 months prior to study entry
Total Enrollment: 70

Location and Contact Information:

Memorial Sloan-Kettering Cancer Center *Recruiting*
New York City,  New York,  10021
United States
Recruiting Barrie  Cassileth


Additional Information:
Study ID Numbers:  1-R21-CA098565-01; 
Study Start Date: 
Record last reviewed: April 2004
Additional information available at: clinicaltrials.gov
Clinicaltrials.gov Reference link: NCT00081965

Other Hot Flashes Studies:
1. Chemotherapy Related Anemia in Patients with Non-Myeloid Malignancies

2. Breast Duct Lavage and Breast Duct Endoscopy for Detecting Breast Cancer

3. A Phase II Study of a Combination of MTA (LY231514) and Gemcitabine in Patients with Metastatic Breast Cancer.

4. Evaluation of BNP7787 for the Prevention of Neurotoxicity in Metastatic Breast Cancer Patients Receiving Weekly Paclitaxel

5. An open-label, multicenter, randomized, controlled study of an investigational drug in postmenopausal women with advanced breast cancer (ABC) having progressed on Tamoxifen.

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