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A Study to Compare the Efficacy and Safety of Pegvisomant to that of Sandostatin LAR in Patients with Acromegaly Clinical Trials Facts presented on Clinical Trials Search is not designed to be a substitute for certified medical advice, travels to or treatment with a real dr.. We aren't doctors. Always consult your mD on A Study to Compare the Efficacy and Safety of Pegvisomant to that of Sandostatin LAR in Patients with Acromegaly conditions. Clinical Trials Search.org is a website dedicated to listing clinical research studies in human subjects. A Study to Compare the Efficacy and Safety of Pegvisomant to that of Sandostatin LAR in Patients with Acromegaly Clinical research trials and A Study to Compare the Efficacy and Safety of Pegvisomant to that of Sandostatin LAR in Patients with Acromegaly medical trials occur in many of places across the U.S.A.. A clinical trial or clinical study is a research project with human volunteer subjects. Clinical drug trials and pharmaceutical clinical trials generally assess the effectiveness of new does drugs. The role of the studies / undertakings is to figure out certain human healthcare questions. Clinical trials are a popular means for doctors, government agencies, and private sector corporations to locate treatments for all forms of circumstances, including A Study to Compare the Efficacy and Safety of Pegvisomant to that of Sandostatin LAR in Patients with Acromegaly. A Study to Compare the Efficacy and Safety of Pegvisomant to that of Sandostatin LAR in Patients with Acromegaly Clinical Trials and other clinical trials permit volunteers to get medical treatment options before they are available to the masses. Most times the human subjects acquire treatment for free of charge, and sometimes they are paid for their time. Occasionally there is a cost for a A Study to Compare the Efficacy and Safety of Pegvisomant to that of Sandostatin LAR in Patients with Acromegaly clinical trial. Participants oftentimes recieve the finest healthcare available for their A Study to Compare the Efficacy and Safety of Pegvisomant to that of Sandostatin LAR in Patients with Acromegaly condition. Dangers are a reality, nonetheless, and might include extra or frequent physician calls, health hazards (potentially life-endangering), and/or the treatment being ineffectual. Trials are federally regulated with strict guidelines to protect clinical trials subjects.

Home > "A" Clinical Trials Conditions > A Study to Compare the Efficacy and Safety of Pegvisomant to that of Sandostatin LAR in Patients with Acromegaly

A Study to Compare the Efficacy and Safety of Pegvisomant to that of Sandostatin LAR in Patients with Acromegaly



A Study to Compare the Efficacy and Safety of Pegvisomant to that of Sandostatin LAR in Patients with Acromegaly

For Condition: Acromegaly
Status: Recruiting
Sponsor(s): Pfizer ,
Synopsis: The pupose of the study is to determine if Pegvisomant is more efficacious than Sandostatin LAR Depot in normalizing IGF-I levels in treatment naive patients with acromegaly.
Details:
Eligibility:
Study Type:
  Interventional, Treatment
Minimum Age/Maximum Age: 18 Years/
Genders: Both
Protocol Entry Criteria: Other specific inclusion/exclusion criteria may apply. In order to determine eligibility, further examination by the investigator is necessary. Inclusion Criteria: - Diagnosis of acromegaly - IGF-I levels >=1.3xULN (upper limit of normal) at screening - No history of radiotherapy or prior treatment with other drugs for acromegaly - Minimum of two months must have elapsed post surgery prior to screening Exclusion Criteria: - Presence of other conditions that may result in abnormal GH (Growth Hormone) and/or IGF-I concentrations - AST/ALT >= 3xULN (upper limit of normal) - Pituitary adenoma within 3mm of optic chiasm confirmed by recent MRI - Visual field defects (except post surgical stable residual defects) - Unable to self administer drug
Total Enrollment: 

Location and Contact Information:

Research Center *Recruiting*
Halifax,  Nova Scotia,  B3H 2YR
Canada
Recruiting  

Research Center *Recruiting*
Manchester,  ,  M20 4BX
United Kingdom
Recruiting  

Research Center *Recruiting*
Stockholm,  ,  171 76
Sweden
Recruiting  

Research Center *Recruiting*
ESSEN,  , 
Germany
Recruiting  

Research Center *Recruiting*
London,  ,  EC1A 78E
United Kingdom
Recruiting  

Research Center *Recruiting*
London,  ,  SE1 7EH
United Kingdom
Recruiting  

Research Center *Recruiting*
Fitzroy,  Victoria,  3065
Australia
Recruiting  

Research Center *Recruiting*
Cleveland,  Ohio,  44106
United States
Recruiting  

Research Center *Recruiting*
Charlottesville,  Virginia,  22908
United States
Recruiting  

Research Center *Recruiting*
Cork,  , 
Ireland
Recruiting  

Research Center *Recruiting*
Sevilla,  ,  41013
Spain
Recruiting  

Research Center *Recruiting*
Leeds,  ,  LS1 3EX
United Kingdom
Recruiting  

Research Center *Recruiting*
Berlin,  ,  10117
Germany
Recruiting  

Research Center *Recruiting*
Montreal,  Quebec,  H2L 2W5
Canada
Recruiting  

Research Center *Recruiting*
Chapel Hill,  North Carolina,  27599
United States
Recruiting  

Research Center *Recruiting*
Genova,  ,  16132
Italy
Recruiting  

Research Center *Recruiting*
Boston,  Massachusetts,  02114
United States
Recruiting  

Research Center *Recruiting*
Chicago,  Illinois, 
United States
Recruiting  

Research Center *Recruiting*
Dublin,  , 
Ireland
Recruiting  

Research Center *Recruiting*
Dresden,  ,  01307
Germany
Recruiting  

Research Center *Recruiting*
Linkoping,  ,  581 85
Sweden
Recruiting  

Research Center *Recruiting*
Torino,  , 
Italy
Recruiting  

Research Center *Recruiting*
Le Kremlin-Bicetre,  ,  94275
France
Recruiting  

Research Center *Recruiting*
Barcelona,  ,  08916
Spain
Recruiting  

Research Center *Recruiting*
Heidelberg,  ,  69120
Germany
Recruiting  

Research Center *Recruiting*
Toronto,  Ontario,  M5G 1X5
Canada
Recruiting  

Research Center *Recruiting*
Roma,  ,  00168
Italy
Recruiting  

Research Center *Recruiting*
Ann Arbor,  Michigan,  48109
United States
Recruiting  

Research Center *Recruiting*
Oslo,  ,  0027
Norway
Recruiting  

Research Center *Recruiting*
Pessac,  ,  33604
France
Recruiting  

Research Center *Recruiting*
Pittsburgh,  Pennsylvania,  15212
United States
Recruiting  

Research Center *Recruiting*
Barcelona,  ,  08907
Spain
Recruiting  

Research Center *Recruiting*
Chicago,  Illinois, 
United States
Recruiting  

Research Center *Recruiting*
Cork,  , 
Ireland
Recruiting  

Research Center *Recruiting*
Belfast,  Ireland,  BT12 6BA
United Kingdom
Recruiting  

Research Center *Recruiting*
Belfast,  ,  BT12 6BA
Ireland
Recruiting  

Research Center *Recruiting*
Madrid,  ,  28035
Spain
Recruiting  


Additional Information:
Study ID Numbers:
  PEGA-0435-003; 
Study Start Date: 
Record last reviewed: May 2004
Additional information available at: clinicaltrials.gov
Clinicaltrials.gov Reference link: NCT00068042

Other Acromegaly Studies:
1. Study of the Effect of Growth Hormone-Releasing Hormone Antagonist on Growth Hormone Release in Acromegaly

2. Measurement of Outcome of Surgical Treatment in Patients With Acromegaly

3. The Treatment and Natural History of Acromegaly

4. A Study to Compare the Efficacy and Safety of Pegvisomant to that of Sandostatin LAR in Patients with Acromegaly

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A Study to Compare the Efficacy and Safety of Pegvisomant to that of Sandostatin LAR in Patients with Acromegaly

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