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A Study of Nystatin in HIV-Infected Patients



A Study of Nystatin in HIV-Infected Patients

For Condition: HIV Infections
Status: Completed
Sponsor(s): Argus Pharmaceuticals ,
Synopsis: To evaluate the clinical toxicity, safety, and potential anti-HIV activity of intravenous nystatin in patients with HIV infection who have completed protocol FDA 103C. To evaluate the safety and potential antiviral activity of intravenous nystatin and oral didanosine (ddI) administered in an alternating regimen in this patient population.
Details: Patients who have completed protocol FDA 103B are offered the option of receiving extended maintenance. Patients who have received no prior ddI are treated either with intravenous nystatin alone (at the same dose level administered in FDA 103B) or with a regimen of intravenous nystatin and ddI alternating on 3-week cycles. Treatment continues for 12 weeks.
Eligibility:
Study Type:  Interventional, Treatment, Dose Comparison, Safety Study
Minimum Age/Maximum Age: 18 Years/
Genders: Both
Protocol Entry Criteria: Inclusion Criteria Patients must have: - Completed 12 weeks of therapy with intravenous nystatin on protocol FDA 103B. - No evidence of toxicity or progression of disease on protocol FDA 103B. (See protocol FDA 103B for initial entry requirements.) Active drug or alcohol abuse.
Total Enrollment: 

Location and Contact Information:

Twelve Oaks Hosp
Houston,  Texas,  77027
United States
 


Additional Information:
Study ID Numbers:  103C;  AR-91-35,606-005A
Study Start Date: 
Record last reviewed: April 1994
Additional information available at: clinicaltrials.gov
Clinicaltrials.gov Reference link: NCT00002313

Other Hiv Infections Studies:
1. Study of Itraconazole in Patients with Advanced HIV Infection

2. The Effects of Giving Interleukin-2 (IL-2) Plus Anti-HIV Therapy to HIV-Positive Patients with CD4 Cell Counts of at Least 350 Cells/mm3

3. Acupuncture and Herbal Treatment of Chronic HIV Sinusitis

4. A Study of Immune System Activity in Healthy Adults

5. A Study of T-20 in HIV-Positive Adults

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A Study of Nystatin in HIV-Infected Patients
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