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A Study of DTC in Patients With AIDS and AIDS Related Complex



A Study of DTC in Patients With AIDS and AIDS Related Complex

For Condition: HIV Infections
Status: Completed
Sponsor(s): Merieux Institute ,
Synopsis: To determine if ditiocarb sodium (sodium diethyldithiocarbamate; DTC) restores immune and host defense function; if DTC ameliorates the AIDS related complex (ARC) symptoms in patients with AIDS and ARC; if DTC prevents progression from ARC to AIDS or progression of AIDS; and if DTC prolongs survival in AIDS.
Details:
Eligibility:
Study Type:  Interventional, Treatment
Minimum Age/Maximum Age: 18 Years/
Genders: Both
Protocol Entry Criteria: Inclusion Criteria Concurrent Medication: Allowed: - Zidovudine (AZT). Exclusion Criteria Co-existing Condition: Patients with the following are excluded: - Active opportunistic infection or progressive Kaposi's sarcoma (KS). - Dementia. - Lymphoma. Concurrent Medication: Excluded within 3 weeks of study entry: - Other experimental AIDS therapy. Patients with the following are excluded: - Active opportunistic infection or progressive Kaposi's sarcoma (KS). Patients must be either HIV seropositive or have AIDS or AIDS related complex (ARC) and have life expectancy of at least 6 months.
Total Enrollment: 

Location and Contact Information:

Portion Med Group
Sherman Oaks,  California,  91403
United States
 

Univ of Arizona / Arizona Cancer Ctr
Tucson,  Arizona,  85724
United States
 

Duke Univ Med Ctr
Durham,  North Carolina,  27710
United States
 

Dr Gary Brewton
Houston,  Texas,  77027
United States
 

San Francisco AIDS Clinic / San Francisco Gen Hosp
San Francisco,  California,  941102859
United States
 

USC School of Medicine / Norris Cancer Hosp
Los Angeles,  California,  90033
United States
 

SUNY / Health Sciences Ctr at Brooklyn
Brooklyn,  New York,  11203
United States
 

Florida Keys Memorial Hosp
Key West,  Florida,  33040
United States
 


Additional Information:
Study ID Numbers:  010A; 
Study Start Date: 
Record last reviewed: July 1989
Additional information available at: clinicaltrials.gov
Clinicaltrials.gov Reference link: NCT00002069

Other Hiv Infections Studies:
1. A Study of Two Forms of Pentamidine in the Treatment of Pneumocystis carinii Pneumonia (PCP) in Patients with AIDS

2. Safety of and Immune Response to a New HIV Vaccine: HIV CTL MEP

3. Safety and Effectiveness of Ritonavir Plus Lamivudine Plus Zidovudine in HIV-Infected Pregnant Women and Their Babies

4. The Effect of Fish Oil Plus Fenofibrate on Triglyceride Levels in People Taking Highly Active Antiretroviral Therapy (HAART)

5. A Study of CI-1012 in HIV-Infected Patients

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