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A Study of Combivir plus Abacavir plus 141W94 in Patients Who Previously Have Used Anti-HIV Drugs Clinical Trials Information presented on Clinical Trials Search isn't intended to be a substitute for proven healthcare advice, trips or treatment using a real physician. We are not docs. Always confer with your mD on A Study of Combivir plus Abacavir plus 141W94 in Patients Who Previously Have Used Anti-HIV Drugs conditions. Clinical Trials Search.org is a site dedicated to listing clinical research studies in human subjects. A Study of Combivir plus Abacavir plus 141W94 in Patients Who Previously Have Used Anti-HIV Drugs Clinical research trials and A Study of Combivir plus Abacavir plus 141W94 in Patients Who Previously Have Used Anti-HIV Drugs medical trials take place in hundreds of localities across the U.S.. A clinical trial or clinical study is a research project with human volunteer subjects. Clinical drug trials and pharmaceutical clinical trials usually measure the effectiveness of new drugs. The intention of the studies / projects is to resolve certain human health questions. Clinical trials are a popular means for physicians, government agencies, and private sector corporations to detect remedies for all forms of circumstances, like A Study of Combivir plus Abacavir plus 141W94 in Patients Who Previously Have Used Anti-HIV Drugs. A Study of Combivir plus Abacavir plus 141W94 in Patients Who Previously Have Used Anti-HIV Drugs Clinical Trials and other clinical trials allow for volunteers to undergo healthcare treatment options before they are available to the masses. Most times the participants receive treatment for free, and every now and again they are paid for their time. Occasionally there is a cost for a A Study of Combivir plus Abacavir plus 141W94 in Patients Who Previously Have Used Anti-HIV Drugs clinical trial. Subjects typically recieve the finest healthcare available for their A Study of Combivir plus Abacavir plus 141W94 in Patients Who Previously Have Used Anti-HIV Drugs condition. Hazards are a reality, nonetheless, and might include more or frequent mD trips, health risks (potentially life-endangering), and/or the treatment being ineffective. Trials are federally regulated with stern guidelines to protect clinical trials subjects.

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A Study of Combivir plus Abacavir plus 141W94 in Patients Who Previously Have Used Anti-HIV Drugs



A Study of Combivir plus Abacavir plus 141W94 in Patients Who Previously Have Used Anti-HIV Drugs

For Condition: HIV Infections
Status: Completed
Sponsor(s): Glaxo Wellcome ,
Synopsis: The purpose of this study is to test the effectiveness of Combivir plus abacavir plus 141W94 in patients who previously have used anti-HIV drugs.
Details: In this open-label study antiretroviral-experienced patients receive Combivir (3TC/AZT tablet) plus 1592U89 (abacavir) and 141W94 twice daily for 48 weeks.
Eligibility:
Study Type:
  Interventional, Treatment, Open Label, Safety Study
Minimum Age/Maximum Age: 18 Years/
Genders: Both
Protocol Entry Criteria: Inclusion Criteria Patients must have: - CD4 count greater than 50 cells/mm3. - HIV RNA less than 50,000 copies/ml. - No active AIDS (excluding CD4 count less than 200 cells/mm3). - Ability to comply with dosing schedule and protocol evaluations. Prior Medication: Allowed: AZT or non-nucleoside reverse transcriptase inhibitors (NNRTIs). Exclusion Criteria Co-existing Condition: Patients with any of the following symptoms or conditions are excluded: - Active AIDS (not excluding CD4 count less than 200). - Malabsorption syndrome affecting drug absorption. - Serious medical condition that would compromise safety of the patient. Concurrent Medication: Excluded: - AZT or NNRTIs. - More than 1 week treatment with any protease inhibitor. - Enrollment in any other investigational drug protocol. Patients with the following prior conditions are excluded: History of clinically relevant pancreatitis or hepatitis within the past 6 months. Required: Antiretroviral therapy with either single or double reverse transcriptase inhibitors.
Total Enrollment: 

Location and Contact Information:

Anderson Clinical Research
Pittsburgh,  Pennsylvania,  15213
United States
 


Additional Information:
Study ID Numbers:
  280D;  UNAP 12,NZTA 4005
Study Start Date: 
Record last reviewed: May 1999
Additional information available at: clinicaltrials.gov
Clinicaltrials.gov Reference link: NCT00002217

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2. A Double-Blind, Randomized, Dose Response Study of Three Doses of Delavirdine Mesylate (U-90152S) in Combination with Zidovudine (ZDV) versus ZDV alone in HIV-1 Infected Individuals with CD4 Counts of 200-500mm3

3. Safety and Effectiveness of Fluconazole Versus SCH 56592 to Treat Thrush in HIV-Positive Patients

4. Prophylaxis Against Tuberculosis (TB) in Patients With Human Immunodeficiency Virus (HIV) Infection and Confirmed Latent Tuberculous Infection

5. The Safety and Effectiveness of Zidovudine in the Treatment of HIV-Infected Children with Mild to Moderate Symptoms

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