Search Clinical Trials
 
By Condition
 
By Location (USA)
 
By Location (Other)
 
By Sponsor
 
Resources
 
Privacy Policy
 
About Us
Disclaimer
A Study of ALRT1057 in Patients with AIDS-Related Kaposi's Sarcoma Clinical Trials Info presented on Clinical Trials Search isn't intended to be a substitute for certified health advice, travels to or treatment by using a genuine physician. We are not physicians. Always consult your dr. on A Study of ALRT1057 in Patients with AIDS-Related Kaposi's Sarcoma conditions. Clinical Trials Search.org is a site committed to listing clinical research studies in human subjects. A Study of ALRT1057 in Patients with AIDS-Related Kaposi's Sarcoma Clinical research trials and A Study of ALRT1057 in Patients with AIDS-Related Kaposi's Sarcoma health trials occur in hundreds of cities throughout the U.S.A.. A clinical trial or clinical study is a research project with human volunteer subjects. Clinical drug trials and pharmaceutical clinical trials typically assess the effectivity of new drugs. The propose of the studies / undertakings is to resolve certain human health questions. Clinical trials are a popular means for physicians, government agencies, and private sector companies to locate treatments for all sorts of conditions, including A Study of ALRT1057 in Patients with AIDS-Related Kaposi's Sarcoma. A Study of ALRT1057 in Patients with AIDS-Related Kaposi's Sarcoma Clinical Trials and other clinical trials permit volunteers to acquire medical treatment choices before they are available to the masses. Some times the test subjects obtain professional assistance for free, and every now and again they are compensated for their time. Sometimes there is a cost for a A Study of ALRT1057 in Patients with AIDS-Related Kaposi's Sarcoma clinical trial. Participants oftentimes recieve the most expert healthcare available for their A Study of ALRT1057 in Patients with AIDS-Related Kaposi's Sarcoma condition. Hazards are a reality, however, and can include extra or frequent physician visits, health risks (potentially life-endangering), and/or the treatment being uneffective. Trials are federally governed with rigorous guidelines to protect clinical trials subjects.

Home > "A" Clinical Trials Conditions > A Study of ALRT1057 in Patients with AIDS-Related Kaposi's Sarcoma

A Study of ALRT1057 in Patients with AIDS-Related Kaposi's Sarcoma



A Study of ALRT1057 in Patients with AIDS-Related Kaposi's Sarcoma

For Condition: Sarcoma, Kaposi,HIV Infections
Status: Completed
Sponsor(s): Anderson Clinical Research , Ligand Pharmaceuticals
Synopsis: The purpose of this study is to see if ALRT1057 is safe and effective in treating patients with AIDS-related Kaposi's sarcoma (KS).
Details: Patients receive open-label ALRT1057 for 16 weeks, as tolerated. In the absence of unacceptable toxicity, patients may continue treatment indefinitely provided they continue to benefit from therapy and the study remains open and active. Thirteen patients are treated initially. If at least one response is observed in these patients, up to 14 additional patients will be evaluated.
Eligibility:
Study Type:  Interventional, Treatment, Safety Study
Minimum Age/Maximum Age: 18 Years/
Genders: Both
Protocol Entry Criteria: Inclusion Criteria Patients must have: - HIV positive status and histologic confirmation of KS. - CD4 count > 200 mm3 (required of one-half of patients). - Minimum of 6 mucocutaneous KS lesions, including at least 3 raised lesions meeting criteria for "indicator" lesions. - Acceptable organ system function. Exclusion Criteria Co-existing Condition: Patients with the following conditions or symptoms are excluded: Serious or intercurrent illness or infection that would interfere with the ability of the patient to carry out the treatment program. Prior Medication: Excluded: - Systemic therapy for KS within 30 days. - Local or topical therapy for KS indicative lesions within 60 days. - Systemic therapy with vitamin A in doses exceeding 15,000 IU per day or other retinoid class drug. Required: Approved antiretroviral therapy.
Total Enrollment: 27

Location and Contact Information:


Additional Information:
Study ID Numbers:  271A;  L1057-28,96ACR-LIG2
Study Start Date: 
Record last reviewed: August 1997
Additional information available at: clinicaltrials.gov
Clinicaltrials.gov Reference link: NCT00002188

Other Sarcoma, Kaposi Studies:
1. A Phase I Study to Evaluate the Safety and Toxicity of the Combination of Zidovudine and 2',3'-Dideoxyinosine (Didanosine) in Children With HIV Infection

2. A Phase I/II Study of the Safety, Tolerance, and Pharmacokinetics of 9-(2-Phosphonylmethoxyethyl)adenine ( PMEA; Adefovir ) in Patients With Advanced HIV Disease.

3. A Study of Valacyclovir as Treatment for Genital Herpes Simplex Virus in HIV-Infected Patients

4. Photodynamic Therapy Clinical Trial For Cutaneous AIDS-Related Kaposi's Sarcoma Study Summary.

5. A Phase I Trial of HIV-1 C4-V3 Polyvalent Peptide Vaccine in HIV-1 Infected Persons

Related Studies:

Other Sarcoma, Kaposi Clinical Trials
Other Clinical Trials
Other Clinical Trials

A Study of ALRT1057 in Patients with AIDS-Related Kaposi's Sarcoma
Modify your Search

  Other Sarcoma, Kaposi Clinical Trials
  Other Clinical Trials
  Other Clinical Trials


Warning: include(/var/www/cgi-bin/traxis/counter.php) [function.include]: failed to open stream: No such file or directory in /home/cts/domains/clinicaltrialssearch.org/public_html/index.php on line 103

Warning: include() [function.include]: Failed opening '/var/www/cgi-bin/traxis/counter.php' for inclusion (include_path='.:/usr/local/lib/php') in /home/cts/domains/clinicaltrialssearch.org/public_html/index.php on line 103