Search Clinical Trials
By Condition
By Location (USA)
By Location (Other)
By Sponsor
Resources
Privacy Policy
About Us
Disclaimer
A Phase I/II Study of Intralesional Recombinant Tumor Necrosis Factor in Patients With AIDS-Related Cutaneous Kaposi's Sarcoma Clinical Trials Resources presented on Clinical Trials Search is not meant to be a substitute for proven health advice, calls or treatment with a real medical. We aren't mDs. Always consult your doctor on A Phase I/II Study of Intralesional Recombinant Tumor Necrosis Factor in Patients With AIDS-Related Cutaneous Kaposi's Sarcoma conditions. Clinical Trials Search.org is a website dedicated to listing clinical research studies in human subjects. A Phase I/II Study of Intralesional Recombinant Tumor Necrosis Factor in Patients With AIDS-Related Cutaneous Kaposi's Sarcoma Clinical research trials and A Phase I/II Study of Intralesional Recombinant Tumor Necrosis Factor in Patients With AIDS-Related Cutaneous Kaposi's Sarcoma healthcare trials take place in a lot of of localities throughout the U.S.. A clinical trial or clinical study is a research project with human volunteer subjects. Clinical drug trials and pharmaceutical clinical trials typically assess the effectiveness of new does drugs. The function of the studies / projects is to figure out specific human medical questions. Clinical trials are a popular means for doctors, government agencies, and private sector corporations to find cures for all varieties of conditions, like A Phase I/II Study of Intralesional Recombinant Tumor Necrosis Factor in Patients With AIDS-Related Cutaneous Kaposi's Sarcoma. A Phase I/II Study of Intralesional Recombinant Tumor Necrosis Factor in Patients With AIDS-Related Cutaneous Kaposi's Sarcoma Clinical Trials and other clinical trials allow volunteers to access health treatment options before they are available to the masses. Many times the subjects receive professional assistance for free, and every now and again they are compensated for their time. Sometimes there is a cost for a A Phase I/II Study of Intralesional Recombinant Tumor Necrosis Factor in Patients With AIDS-Related Cutaneous Kaposi's Sarcoma clinical trial. Human subjects often obtain the finest healthcare possible for their A Phase I/II Study of Intralesional Recombinant Tumor Necrosis Factor in Patients With AIDS-Related Cutaneous Kaposi's Sarcoma condition. Hazards are a reality, nevertheless, and might include additional or frequent dr. calls, health hazards (potentially life-jeopardizing), and/or the treatment being uneffective. Trials are federally regulated with stern guidelines to protect clinical trials patients.

Home > "A" Clinical Trials Conditions > A Phase I/II Study of Intralesional Recombinant Tumor Necrosis Factor in Patients With AIDS-Related Cutaneous Kaposi's Sarcoma

A Phase I/II Study of Intralesional Recombinant Tumor Necrosis Factor in Patients With AIDS-Related Cutaneous Kaposi's Sarcoma



A Phase I/II Study of Intralesional Recombinant Tumor Necrosis Factor in Patients With AIDS-Related Cutaneous Kaposi's Sarcoma

For Condition: Sarcoma, Kaposi,HIV Infections
Status: Completed
Sponsor(s): University of California, San Francisco ,
Synopsis: To evaluate tolerance, toxicity, and preliminary evidence of antitumor efficacy of intralesionally administered tumor necrosis factor (TNF) and to define a maximum tolerated dose (MTD) for single intralesional injections. In addition, to assess the effects of TNF injections on Kaposi's sarcoma (KS) lesions as measured by P-32 magnetic resonance spectroscopy.
Details:
Eligibility:
Study Type:
  Interventional, Treatment, Dose Comparison
Minimum Age/Maximum Age: 18 Years/70 Years
Genders: Male
Protocol Entry Criteria: Inclusion Criteria Patients must have: - Biopsy-proven Kaposi's sarcoma (KS) with multiple cutaneous lesions. - Minimum life expectancy of 3 months. Exclusion Criteria Co-existing Condition: Patients with the following conditions or symptoms are excluded: - Clinically significant cardiac disease. - Known hemorrhagic diathesis or active bleeding disorder. - Clinically apparent vascular disease. - Known lipoprotein disorders. - History of seizure disorder or central nervous system (CNS) metastasis. - Additional malignancy. Concurrent Medication: Excluded: - Cardiac agents. - Anticoagulants. - Thrombolytic agents. - Nonsteroidal anti-inflammatory drugs. - Corticosteroids. - Aspirin. - Vasodilators. Patients with the following are excluded: - Additional malignancies or other conditions listed in Patient Exclusion Co-Existing Conditions. Prior Treatment: Excluded within 4 weeks of study entry: - Chemotherapy. - Radiotherapy. - Immunotherapy.
Total Enrollment: 

Location and Contact Information:

San Francisco AIDS Clinic / San Francisco Gen Hosp
San Francisco,  California,  941102859
United States
 


Additional Information:
Study ID Numbers:
  066A;  86-989
Study Start Date: 
Record last reviewed: December 1988
Additional information available at: clinicaltrials.gov
Clinicaltrials.gov Reference link: NCT00002262

Other Sarcoma, Kaposi Studies:
1. A Study of Chemotherapy Plus Azidothymidine in the Treatment of Kaposi's Sarcoma in Patients with AIDS

2. A Phase I Study of AZT and Human Interferon Alpha (Recombinant Alpha-2A and Lymphoblastoid) in the Treatment of AIDS-Associated Kaposi's Sarcoma

3. The Safety and Effectiveness of Interferon Alfa-2B Plus Didanosine in Patients with Kaposi's Sarcoma

4. The Safety and Effectiveness of Ritonavir in the Treatment of HIV-Related Kaposi's Sarcoma

5. A Phase I Trial of Tecogalan sodium ( DS-4152 ) Administered as an Infusion Twice Weekly for 21 Days.

Related Studies:

Other Sarcoma, Kaposi Clinical Trials
Other California Clinical Trials
Other San Francisco Clinical Trials

A Phase I/II Study of Intralesional Recombinant Tumor Necrosis Factor in Patients With AIDS-Related Cutaneous Kaposi's Sarcoma

Modify your Search

  Other Sarcoma, Kaposi Clinical Trials
  Other California Clinical Trials
  Other San Francisco Clinical Trials


Warning: include(/var/www/cgi-bin/traxis/counter.php) [function.include]: failed to open stream: No such file or directory in /home/cts/domains/clinicaltrialssearch.org/public_html/index.php on line 103

Warning: include() [function.include]: Failed opening '/var/www/cgi-bin/traxis/counter.php' for inclusion (include_path='.:/usr/local/lib/php') in /home/cts/domains/clinicaltrialssearch.org/public_html/index.php on line 103