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A Phase III Study of Entecavir vs Lamivudine in Adults with Chronic Hepatitis B Infection and negative for Hepatitis B e Antigen Clinical Trials Data presented on Clinical Trials Search isn't meant to be a substitute for qualified health advice, calls or treatment using a genuine doctor. We are not docs. Always consult your dr. on A Phase III Study of Entecavir vs Lamivudine in Adults with Chronic Hepatitis B Infection and negative for Hepatitis B e Antigen conditions. Clinical Trials Search.org is a site dedicated to listing clinical research studies in human subjects. A Phase III Study of Entecavir vs Lamivudine in Adults with Chronic Hepatitis B Infection and negative for Hepatitis B e Antigen Clinical research trials and A Phase III Study of Entecavir vs Lamivudine in Adults with Chronic Hepatitis B Infection and negative for Hepatitis B e Antigen healthcare trials occur in a lot of of places throughout the United States. A clinical trial or clinical study is a research project with human volunteer subjects. Clinical drug trials and pharmaceutical clinical trials generally assess the potency of new drugs. The intent of the studies / undertakings is to figure out certain human medical questions. Clinical trials are a popular means for mDs, government agencies, and private sector corporations to locate remedies for all kinds of circumstances, including A Phase III Study of Entecavir vs Lamivudine in Adults with Chronic Hepatitis B Infection and negative for Hepatitis B e Antigen. A Phase III Study of Entecavir vs Lamivudine in Adults with Chronic Hepatitis B Infection and negative for Hepatitis B e Antigen Clinical Trials and other clinical trials allow volunteers to obtain health treatment alternatives before they are available to the masses. Many times the participants undergo treatment for free, and sometimes they are paid for their time. Occasionally there is a cost for a A Phase III Study of Entecavir vs Lamivudine in Adults with Chronic Hepatitis B Infection and negative for Hepatitis B e Antigen clinical trial. Participants typically obtain the most effective healthcare available for their A Phase III Study of Entecavir vs Lamivudine in Adults with Chronic Hepatitis B Infection and negative for Hepatitis B e Antigen condition. Dangers are a reality, nonetheless, and can include extra or frequent mD trips, medical hazards (potentially life-endangering), and/or the treatment being uneffective. Trials are federally regulated with rigid guidelines to protect clinical trials patients.

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A Phase III Study of Entecavir vs Lamivudine in Adults with Chronic Hepatitis B Infection and negative for Hepatitis B e Antigen



A Phase III Study of Entecavir vs Lamivudine in Adults with Chronic Hepatitis B Infection and negative for Hepatitis B e Antigen

For Condition: Chronic Hepatitis B
Status: No longer recruiting
Sponsor(s): Bristol-Myers Squibb ,
Synopsis: The purpose of this clinical research study is to assess the safety and effectiveness of entecavir, as compared to lamivudine, in the treatment of adults with chronic hepatitis B infection who are hepatitis B e antigen negative.
Details:
Eligibility:
Study Type:
  Interventional, Treatment
Minimum Age/Maximum Age: 16 Years/
Genders: Both
Protocol Entry Criteria: - Male and female subjects =/> 16 years of age (or minimum age required in a given country) with history of chronic hepatitis B infection; - HBeAg negative, anti-HBeAb positive; - Absence of coinfection with human immunodeficiency virus (HIV), hepatitis C virus (HCV) or hepatitis D virus (HDV); - Absence of other forms of liver disease e.g., alcoholic, autoimmune, biliary disease; - Less than 12 weeks prior therapy with nucleoside or nucleotide analogue antiviral agents with activity against hepatitis B (e.g., adefovir, famciclovir and lamivudine)
Total Enrollment: 

Location and Contact Information:

Local Investigator
Worcester,  Massachusetts, 
United States
 

Local Investigator
Dundalk,  Maryland, 
United States
 

Local Investigator
Richmond,  Virginia, 
United States
 

Local Investigator
Providence,  Rhode Island, 
United States
 

Local Investigator
Orange,  California, 
United States
 

Local Investigator
Ann Arbor,  Michigan, 
United States
 

Local Investigator
Charlotte,  North Carolina, 
United States
 

Local Investigator
Rochester,  New York, 
United States
 

Local Investigator
Miami,  Florida, 
United States
 

Local Investigator
Seattle,  Washington, 
United States
 

Local Investigator
Los Angeles,  California,  90048
United States
 

Local Investigator
Cleveland,  Ohio, 
United States
 

Local Investigator
Manhasset,  New York, 
United States
 

Local Investigator
Philadelphia,  Pennsylvania, 
United States
 

Local Investigator
La Jolla,  California, 
United States
 

Local Investigator
Dallas,  Texas, 
United States
 

Local Investigator
Atlanta,  Georgia,  30322
United States
 

Local Investigator
Honolulu,  Hawaii, 
United States
 

Local Investigator
San Francisco,  California, 
United States
 

Local Investigator
New York City,  New York, 
United States
 

Local Investigator
Iowa City,  Iowa, 
United States
 

Local Investigator
Birmingham,  Alabama, 
United States
 

Local Investigator
Royal Oak,  Michigan, 
United States
 

Local Investigator
Nashville,  Tennessee,  37211
United States
 

Local Investigator
New York City,  New York, 
United States
 

Local Investigator
Chicago,  Illinois,  60622
United States
 

Local Investigator
Fairfax,  Virginia, 
United States
 

Local Investigator
Tucson,  Arizona, 
United States
 

Local Investigator
New York City,  New York, 
United States
 

Local Investigator
Pittsburgh,  Pennsylvania, 
United States
 

Local Investigator
Farmington,  Connecticut, 
United States
 

Local Investigator
St. Paul,  Minnesota, 
United States
 

Local Investigator
Kansas City,  Kansas, 
United States
 


Additional Information:
Study ID Numbers:
  AI463-027; 
Study Start Date: 
Record last reviewed: February 2004
Additional information available at: clinicaltrials.gov
Clinicaltrials.gov Reference link: NCT00035789

Other Chronic Hepatitis B Studies:
1. An Open-Label Program of Adefovir Dipivoxil in the Treatment of Patients with Lamivudine-Resistant Chronic Hepatitis B With Limited Treatment Options

2. A Phase III Study of Entecavir vs Lamivudine in Adults with Chronic Hepatitis B Infection and negative for Hepatitis B e Antigen

3. Lamivudine and Adefovir to Treat Chronic Hepatitis B Infection in People With and Without HIV Infection

4. Safety and antiviral study of ACH126, 433 (b-L-Fd4C) in adults with lamivudine-resistant chronic hepatitis B

5. Efficacy and safety study of Pegasys in the treatment of chronic hepatitis B

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A Phase III Study of Entecavir vs Lamivudine in Adults with Chronic Hepatitis B Infection and negative for Hepatitis B e Antigen

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