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A Phase II Study of Continuous versus Syncopated Dosing of CC-5013 for the Treatment of Refractory Multiple Myeloma



A Phase II Study of Continuous versus Syncopated Dosing of CC-5013 for the Treatment of Refractory Multiple Myeloma

For Condition: Multiple Myeloma
Status: Recruiting
Sponsor(s): Celgene Corporation ,
Synopsis: To evaluate the response rate, response duration, and survival of patients treated with CC-5013 in a chronic dosing schedule versus a syncopated dosing schedule.
Details:
Eligibility:
Study Type:
  Interventional, Treatment, Randomized, Open Label, Active Control, Parallel Assignment, Safety/Efficacy Study
Minimum Age/Maximum Age: 18 Years/
Genders: Both
Protocol Entry Criteria: - History of histologically documented multiple myeloma with relapsed or resistant disease - Pregnant or nursing women may not participate. Women of childbearing potential must have a negative pregnancy documented within one week of registration. Women of reproductive potential may not participate unless they have agreed to use an effective contraceptive method. - Signed written informed consent and willingness to meet follow-up schedule and study procedure obligations
Total Enrollment: 100

Location and Contact Information:

Myeloma Institute University of Arkansas for Medical Sciences *Recruiting*
Little Rock,  Arkansas,  72205
United States
Recruiting Jenifer  Prather 501-296-1503


Additional Information:
Study ID Numbers:
  CC-5013-MM-008; 
Study Start Date: May 2002
Record last reviewed: May 2004
Additional information available at: clinicaltrials.gov
Clinicaltrials.gov Reference link: NCT00051116

Other Multiple Myeloma Studies:
1. Ondansetron in Treating Patients With Advanced Cancer and Chronic Nausea and Vomiting Not Caused by Cancer Treatment

2. A Study of PS-341 Given to Patients With Multiple Myeloma who Experienced Progressive Disease After Receiving Dexamethasone in M34101-039

3. Combination Chemotherapy With or Without Idarubicin and Peripheral Stem Cell Transplantation in Treating Patients With Leukemia or Myelodysplastic Syndrome

4. Treatment with Zometa in patients with breast cancer, multiple myeloma, and prostate cancer with cancer related bone lesions

5. Itraconazole Compared With Fluconazole to Prevent Infections in Patients Undergoing Peripheral Stem Cell or Bone Marrow Transplantation

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A Phase II Study of Continuous versus Syncopated Dosing of CC-5013 for the Treatment of Refractory Multiple Myeloma

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