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A Phase II Open-Label Exploratory Study of Saquinavir + Zidovudine + Lamivudine in HIV Infected Patients



A Phase II Open-Label Exploratory Study of Saquinavir + Zidovudine + Lamivudine in HIV Infected Patients

For Condition: HIV Infections
Status: Completed
Sponsor(s): Hoffmann-La Roche ,
Synopsis: To explore the antiviral efficacy, tolerability and safety of saquinavir plus zidovudine plus lamivudine.
Details: A total of 30 patients receive the triple drug regimen saquinavir plus zidovudine plus lamivudine until the completion of the analysis after at least 4 weeks of therapy.
Eligibility:
Study Type:
  Interventional, Treatment, Safety Study
Minimum Age/Maximum Age: 18 Years/
Genders: Both
Protocol Entry Criteria: Inclusion Criteria Patients must have: - HIV antibody positive. - CD4 count >= 150 and <= 500 cells/mm3. Exclusion Criteria Prior Medication: Excluded: - Prior antiretroviral therapy. - Prior protease inhibitor therapy.
Total Enrollment: 30

Location and Contact Information:

Pacific Oaks Med Group / Rsch & Scientific Investigation
Sherman Oaks,  California,  91403
United States
 

Davies Med Ctr / c/o HIV Institute
San Francisco,  California,  94114
United States
 

Columbia Presbyterian Med Ctr
New York City,  New York,  10032
United States
 


Additional Information:
Study ID Numbers:
  229N;  NV15114
Study Start Date: 
Record last reviewed: July 1997
Additional information available at: clinicaltrials.gov
Clinicaltrials.gov Reference link: NCT00002190

Other Hiv Infections Studies:
1. A Study of Indinavir Sulfate Plus Zidovudine (AZT) Plus Lamivudine in HIV-Infected Patients Who Have Taken AZT for Six or More Months

2. When to Start Anti-HIV Drugs in Patients with Opportunistic Infections

3. Dual Boosted- PI PK trial

4. The Effects of Anti-HIV Therapy on the Immune Systems of Children Infected With HIV

5. A Phase I, Open Label Trial to Evaluate the Safety, Tolerance and Biological Effects of SDZ ILE-964 (Recombinant Human Interleukin-3, RhIL-3) in HIV Infected Patients with Cytopenia

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A Phase II Open-Label Exploratory Study of Saquinavir + Zidovudine + Lamivudine in HIV Infected Patients

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