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A phase II multicenter uncontrolled trial of BAY 43-9006 in patients with advanced hepatocellular carcinoma



A phase II multicenter uncontrolled trial of BAY 43-9006 in patients with advanced hepatocellular carcinoma

For Condition: Carcinoma, Hepatocellular
Status: Recruiting
Sponsor(s): Bayer Corporation ,
Synopsis: The primary objective of the study is to evaluate the anti-cancer activity (e.g. proportion of patients with confirmed complete responses and partial responses as per the WHO criteria) in patients with advanced inoperable biopsy-proven hepatocellular carcinoma. The secondary objectives are as follows: * To determine duration of response, time
Details:
Eligibility:
Study Type:
  Interventional, Treatment, Non-Randomized, Open Label, Uncontrolled, Single Group Assignment, Safety/Efficacy Study
Minimum Age/Maximum Age: 18 Years/
Genders: Both
Protocol Entry Criteria: - Patients with measurable, histologically or cytologically documented hepatocellular carcinoma, which is inoperable. - Patients must have previously untreated disease (except for local therapy). - No prior chemotherapy is permitted.
Total Enrollment: 135

Location and Contact Information:

Memorial Sloan Kettering Cancer center *Recruiting*
New York City,  New York,  00014
United States
Recruiting Leonard  Saltz 212-639-2501


Additional Information:
Study ID Numbers:
  100874;  100874
Study Start Date: August 2002
Record last reviewed: March 2004
Additional information available at: clinicaltrials.gov
Clinicaltrials.gov Reference link: NCT00048919

Other Carcinoma, Hepatocellular Studies:
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3. Safety and Efficacy Study of a Caspase Inhibitor in Patients Undergoing Liver Transplantation

4. A Trial of Thymalfasin in Adult Patients with Hepatocellular Carcinoma

5. A Safety and Efficacy Study of DENSPM in Patients with Liver Cancer who are Not Eligible for Surgical Cure

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