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A Comparison of Emtricitabine and Abacavir Used in a Three-Drug Combination in HIV-Infected Patients Who Have Never Taken Anti-HIV Drugs Clinical Trials Facts presented on Clinical Trials Search isn't designed to be a substitute for proven healthcare advice, calls or treatment using a real mD. We aren't mDs. Always confer with your physician on A Comparison of Emtricitabine and Abacavir Used in a Three-Drug Combination in HIV-Infected Patients Who Have Never Taken Anti-HIV Drugs conditions. Clinical Trials Search.org is a website dedicated to listing clinical research studies in human subjects. A Comparison of Emtricitabine and Abacavir Used in a Three-Drug Combination in HIV-Infected Patients Who Have Never Taken Anti-HIV Drugs Clinical research trials and A Comparison of Emtricitabine and Abacavir Used in a Three-Drug Combination in HIV-Infected Patients Who Have Never Taken Anti-HIV Drugs healthcare trials happen in a lot of of localities across the United States of America. A clinical trial or clinical study is a research project with human volunteer subjects. Clinical drug trials and pharmaceutical clinical trials generally measure the potency of new drugs. The aim of the studies / undertakings is to answer particular human medical questions. Clinical trials are a popular manner for doctors, government agencies, and private sector corporations to discover remedies for all kinds of circumstances, such as A Comparison of Emtricitabine and Abacavir Used in a Three-Drug Combination in HIV-Infected Patients Who Have Never Taken Anti-HIV Drugs. A Comparison of Emtricitabine and Abacavir Used in a Three-Drug Combination in HIV-Infected Patients Who Have Never Taken Anti-HIV Drugs Clinical Trials and other clinical trials allow volunteers to get healthcare treatment alternatives before they are available to the general public. Most times the participants receive treatment for without cost, and occasionally they are paid for their time. Sometimes there is a cost for a A Comparison of Emtricitabine and Abacavir Used in a Three-Drug Combination in HIV-Infected Patients Who Have Never Taken Anti-HIV Drugs clinical trial. Human subjects often receive the most effective healthcare possible for their A Comparison of Emtricitabine and Abacavir Used in a Three-Drug Combination in HIV-Infected Patients Who Have Never Taken Anti-HIV Drugs condition. Risks are a reality, nonetheless, and may include more or frequent dr. calls, healthcare hazards (perhaps life-threatening), and/or the treatment being ineffective. Trials are federally governed with rigorous guidelines to protect clinical trials subjects.
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Home > "A" Clinical Trials Conditions > A Comparison of Emtricitabine and Abacavir Used in a Three-Drug Combination in HIV-Infected Patients Who Have Never Taken Anti-HIV Drugs A Comparison of Emtricitabine and Abacavir Used in a Three-Drug Combination in HIV-Infected Patients Who Have Never Taken Anti-HIV Drugs
A Comparison of Emtricitabine and Abacavir Used in a Three-Drug Combination in HIV-Infected Patients Who Have Never Taken Anti-HIV Drugs
For Condition: HIV Infections
Status: Suspended
Sponsor(s): Triangle Pharmaceuticals ,
Synopsis: This study will look at whether emtricitabine is as safe and effective as abacavir (ABC) when taken with stavudine (d4T) and efavirenz (EFV) in patients who have never taken anti-HIV drugs.
Details: Patients are randomized to receive open-label emtricitabine or ABC in combination with stavudine and efavirenz. Viral load and CD4+ cell counts are compared at Weeks 24 and 48. Patients are followed for 48 weeks.
Eligibility:
Study Type: Interventional, Treatment, Safety Study
Minimum Age/Maximum Age: 18 Years/
Genders: Both
Protocol Entry Criteria: Inclusion Criteria You may be eligible if you: - Are HIV-positive and generally healthy. - Have a viral load of 5,000 copies/ml or more. - Have CD4 cell counts of 200 cells/mm3 or more. - Are age 18 or older. - Agree to practice sexual abstinence or use effective barrier methods of birth control (such as condoms). Exclusion Criteria You will not be eligible if you: - Have ever taken anti-HIV drugs for 3 days or more. - Have had certain AIDS-related infections. - Have had severe diarrhea within the past 30 days. - Are unable to eat at least 1 meal a day due to nausea, vomiting, or stomach pain. - Are being treated for active tuberculosis (TB). - Are pregnant or breast-feeding. - Use illegal drugs or alcohol that make it difficult for you to take study drugs or keep clinic appointments. - Are taking certain medications, or have certain other conditions or diseases (see the technical summary for more detail).
Total Enrollment:
Location and Contact Information:
Northstar Med Clinic
Chicago, Illinois, 60657
United States
Univ of Texas / Med School at Houston
Houston, Texas, 77030
United States
Houston Clinical Research Network
Houston, Texas, 77006
United States
Gary Richmond MD
Ft. Lauderdale, Florida, 33316
United States
Univ of Texas Southwestern Med Ctr of Dallas
Dallas, Texas, 75235
United States
Ctr for AIDS Research / Education and Service (CARES)
Sacramento, California, 95814
United States
South Jersey Infectious Diseases Inc
Somers Point, New Jersey, 08244
United States
North Shore Univ Hosp / Div of Infectious Diseases
Manhasset, New York, 11030
United States
San Francisco Veterans Administration Med Ctr
San Francisco, California, 94121
United States
Univ of Texas Health Sciences Ctr
San Antonio, Texas, 78284
United States
Additional Information:
Study ID Numbers: 298B; FTC-301
Study Start Date: August 1999
Record last reviewed: March 2000
Additional information available at: clinicaltrials.gov
Clinicaltrials.gov Reference link: NCT00002362
Other Hiv Infections Studies:
1. A Study of Zidovudine Plus Interleukin-2 in HIV-Infected Patients Who Have No Symptoms of Infection But Who Have Tender Lymph Nodes
2. The Safety and Effectiveness of Methylprednisolone in the Treatment of Pneumocystis carinii Pneumonia (PCP) in Children with AIDS
3. A Phase I Safety and Immunogenicity Trial of UBI Multivalent HIV-1 Peptide Immunogen in HIV-1 Seronegative Human Subjects
4. A Phase I Study of the Safety and Pharmacokinetics of Recombinant CD4 (rCD4) in Patients With AIDS and AIDS-Related Complex
5. Safety and Effectiveness of a Combination Anti-HIV Drug Treatment
Related Studies:
Other HIV Infections Clinical Trials
Other Texas Clinical Trials
Other Houston Clinical Trials
A Comparison of Emtricitabine and Abacavir Used in a Three-Drug Combination in HIV-Infected Patients Who Have Never Taken Anti-HIV Drugs
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