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A Comparison of BMS-232632 with Efavirenz, Each in Combination with Zidovudine-Lamivudine Clinical Trials References presented on Clinical Trials Search is not intended to be a substitute for proven healthcare advice, trips or professional assistance by using a real medical. We aren't mDs. Always confer with your physician about A Comparison of BMS-232632 with Efavirenz, Each in Combination with Zidovudine-Lamivudine conditions. Clinical Trials Search.org is a website devoted to listing clinical research studies in human subjects. A Comparison of BMS-232632 with Efavirenz, Each in Combination with Zidovudine-Lamivudine Clinical research trials and A Comparison of BMS-232632 with Efavirenz, Each in Combination with Zidovudine-Lamivudine medical trials take place in hundreds of localities across the U.S.. A clinical trial or clinical study is a research project with human volunteer subjects. Clinical drug trials and pharmaceutical clinical trials usually evaluate the effectualness of new does drugs. The purpose of the studies / projects is to solve specific human health questions. Clinical trials are a popular way for physicians, government agencies, and private sector companies to discover treatments for all sorts of conditions, such as A Comparison of BMS-232632 with Efavirenz, Each in Combination with Zidovudine-Lamivudine. A Comparison of BMS-232632 with Efavirenz, Each in Combination with Zidovudine-Lamivudine Clinical Trials and other clinical trials permit volunteers to access healthcare treatment choices before they are available to the general public. Some times the subjects recieve professional assistance for without cost, and every now and again they are compensated for their time. Sometimes there is a cost for a A Comparison of BMS-232632 with Efavirenz, Each in Combination with Zidovudine-Lamivudine clinical trial. Subjects often receive the most expert healthcare possible for their A Comparison of BMS-232632 with Efavirenz, Each in Combination with Zidovudine-Lamivudine condition. Risks are a reality, nevertheless, and could include additional or frequent dr. calls, healthcare dangers (perhaps life-jeopardising), and/or the treatment being ineffective. Trials are federally governed with stern guidelines to protect clinical trials subjects.
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Home > "A" Clinical Trials Conditions > A Comparison of BMS-232632 with Efavirenz, Each in Combination with Zidovudine-Lamivudine  A Comparison of BMS-232632 with Efavirenz, Each in Combination with Zidovudine-Lamivudine
A Comparison of BMS-232632 with Efavirenz, Each in Combination with Zidovudine-Lamivudine
For Condition: HIV Infections
Status: No longer recruiting
Sponsor(s): Bristol-Myers Squibb ,
Synopsis: The purpose of this study is to compare the effectiveness of treatment with BMS-232632 to that of efavirenz (EFV) when both are used with zidovudine (ZDV) and lamivudine (3TC).
Details: This is a multinational, 2-arm study. Patients in 1 arm receive BMS-232632 plus EFV placebo capsules. Patients in the other arm receive EFV plus BMS-232632 placebo. Both arms also receive a fixed dose of ZDV-3TC.
Eligibility:
Study Type: Interventional, Treatment, Double-Blind
Minimum Age/Maximum Age: 16 Years/
Genders: Both
Protocol Entry Criteria: Inclusion Criteria Patients may be eligible for this study if they: - Have a viral load of 2,000 or more copies/ml and a CD4 cell count of 100 or more cells/mm3 (or 75 or more cells/mm3 with no prior history of AIDS-defining diagnosis) within 2 weeks before randomization. - Are at least 16 years old. - Have signed consent of parent or guardian if under 18 years of age. - Are willing to use effective barrier methods of birth control. - Are available for follow-up for at least 52 weeks. Exclusion Criteria Patients will not be eligible for this study if they: - Have had anti-HIV treatment within 30 days before screening. - Have a recently diagnosed HIV-related infection. - Have any medical condition requiring treatment at enrollment. - Have recently become HIV infected. - Have acute hepatitis within 30 days of study entry. Certain patients with chronic hepatitis will be eligible. - Expect to need or have taken drugs with myelosuppressive, neurotoxic, pancreatotoxic, hepatotoxic, or cytotoxic potential within 3 months before study. Expect to need methadone, ribavirin/interferons, neurotoxic drugs or drugs that affect CYP3A4. - Abuse alcohol or drugs. - Have severe diarrhea within 30 days before study entry. - Are pregnant or breast-feeding. - Have a history of hemophilia. - Have a history of bilateral peripheral neuropathy. - Cannot take medicines by mouth. - Have any other conditions that the doctor thinks would interfere with the study.
Total Enrollment:
Location and Contact Information:
Ospedale degli Infermi
Rimini, ,
Italy
Hosp Edgardo Rebagliati
Lima, ,
Peru
Associates in Research
Ft. Myers, Florida, 33901
United States
Chiangmai Univ
Chiang Mai, ,
Thailand
Rajavithi Hosp
Bangkok, ,
Thailand
Tygerberg Hosp
Cape Town, ,
South Africa
Hosp Clinic
Barcelona, ,
Spain
Kaplan Med Ctr
Rehovot, ,
Israel
Infectious Hosp 30
St Petersburg, ,
Russian Federation
Hosp Sotero de Rio
Santiago, ,
Chile
ID Care Inc
Somerville, New Jersey, 08876
United States
Hosp Vargas de Caracas
Caracas, ,
Venezuela
Hosp Germans Trias I Pujol
Barcelona, ,
Spain
Saint Laszlo Hosp
Budapest, ,
Hungary
Vajira Hosp
Bangkok, ,
Thailand
Gary Rubin
Toronto, Ontario,
Canada
Montrose Clinic
Houston, Texas, 77006
United States
Duke Univ Med Ctr / Infectious Disease Clinic
Durham, North Carolina, 27710
United States
Univ Zu Koeln
Koeln, ,
Germany
Ospedale Amedeo di Savoia
Torino, ,
Italy
Oaklawn Physicians Group
Dallas, Texas, 75219
United States
Siriraj Hosp / Mahidol Univ
Bangkok, ,
Thailand
Jemsek Clinic
Huntersville, North Carolina, 28078
United States
Hosp Nuestra Senora de Covadonga
Oviedo, ,
Spain
Julio Arroyo
West Columbia, South Carolina, 29169
United States
Services des Maladies Infectieuses
Paris Cedex 12, ,
France
Emory Univ
Atlanta, Georgia, 30308
United States
Royal Free Hosp
London, ,
United Kingdom
Dr Bruce Rashbaum
Washington D.C., District of Columbia, 20037
United States
Ramathibodi Hosp
Bangkok, ,
Thailand
Hosp Guillermo Almenara-Medicina 1
Lima, ,
Peru
Servicio de Dermatologia-Hosp del Salvador
Santiago, ,
Chile
Dupont Circle Physicians Group
Washington D.C., District of Columbia, 200091104
United States
San Juan VAMC
San Juan, , 009265800
Puerto Rico
Univ of Alberta/Division of Inf Dis/Dept of Med
Edmonton, Alberta,
Canada
Washington Univ School of Medicine
St. Louis, Missouri, 63108
United States
CHU Saint Pierre
Brussels, ,
Belgium
Saint James Hosp
Dublin, ,
United Kingdom
Fundacion Arriaran
Santiago, ,
Chile
Tarrant County Infectious Diseases Associates
Ft. Worth, Texas, 76104
United States
Ohio State Univ Hosp
Columbus, Ohio, 432101282
United States
Univ of British Columbia
Vancouver, British Columbia,
Canada
Immunoligia Universita Cagliari
Cagliari, ,
Italy
Hosp Roosevelt Chief Infectious Diseases Unit
Guatemala, ,
Guatemala
Univ of Michigan Hospitals and Health Ctrs
Ann Arbor, Michigan, 481090378
United States
Univ of Malaya Med Ctr
Kuala Lumpur, ,
Malaysia
Pulmologisches Zentrum Der Stadt Wien
Wien, ,
Austria
Clinical Research Puerto Rico Inc
San Juan, , 009091711
Puerto Rico
Universitatsspital Zurich
Zurich, ,
Switzerland
Ust Izhora Fed Infectious Hosp
St Petersburg, ,
Russian Federation
Hosp Dr Domingo Luciani
Miranda, ,
Venezuela
Methodist Healthcare
Memphis, Tennessee, 38104
United States
Ospedale S Raffaele
Milano, ,
Italy
Federal AIDS Ctr
Moscow, ,
Russian Federation
Hopital Hotel Dieu de Lyon
Lyon, ,
France
Phoenix Body Positive
Phoenix, Arizona, 85006
United States
Univ of Kansas School of Medicine
Wichita, Kansas, 672143124
United States
Univ of Southern California
Los Angeles, California, 90033
United States
AKH Wien
Wien, ,
Austria
Hosp General San Juan de Dios
Guatemala, ,
Guatemala
Rheinische Friedrich Wilhelms Universitaet Medizinische
Bonn, ,
Germany
North Broward Hosp District / HIV Clinical Research
Ft. Lauderdale, Florida, 33311
United States
Ospedale Amedeo de Savoia
Torino, ,
Italy
Philadelphia FIGHT
Philadelphia, Pennsylvania, 19107
United States
Hosp Clinico de La Pontificia Universidad Catolica de Chile
Santiago, ,
Chile
Hosp Virgen Del Rocio
Sevilla, ,
Spain
The CORE Ctr
Chicago, Illinois, 60612
United States
Steinhart Medical Associates
Miami, Florida, 33133
United States
Hopital Cochin - Port Royal
Paris, ,
France
Chris Hani Baragwanath Hosp
Johannesburg, ,
South Africa
Saint Francis Mem Hosp / HIV Care Unit
San Francisco, California, 94109
United States
Hosp De Sao Joao
Porto, ,
Portugal
McMaster Univ Med Ctr
Hamilton, Ontario,
Canada
Toga Lab
Johannesburg, ,
South Africa
Saint Josephs Comprehensive Research Institute
Tampa, Florida, 33607
United States
Robert Wood Johnson Med School/UMDNJ
New Brunswick, New Jersey, 089030019
United States
UMDNJ - New Jersey Med School
Newark, New Jersey, 071032757
United States
Ospedale S Orsola
Bologna, ,
Italy
King's College Hosp
Cambewell, ,
United Kingdom
Hosp Ramon y Cajal
Madris, ,
Spain
Hosp Reina Sofia
Cordoba, ,
Spain
Hosp U de Caracas / Ciudad
Caracas, ,
Venezuela
Hosp de Basurto / Enfermedades Infecciosas
Bilboa, ,
Spain
Univ of NM
Albuquerque, New Mexico, 87131
United States
Hosp Nacional Arzobispo Loayza-PROCETS
Lima, ,
Peru
UZ Gasthuisberg
Leuven, ,
Belgium
Ospedale Luigi Sacco Cargnel
Milano, ,
Italy
Univ of Nebraska Medical Ctr
Omaha, Nebraska, 681985400
United States
Brooklyn Med Ctr
Cape Town, ,
South Africa
Cat All Immun Clin
Roma, ,
Italy
Hosp Nacional dos de Mayo
Lima, ,
Peru
Hosp De Santa Maria
Lisboa, ,
Portugal
Hosp Carlos III
Madrid, ,
Spain
Hosp Kuala Lumpur
Kuala Lumpur, ,
Malaysia
Hospital Gustave Dron
Tourcoing, ,
France
Hosp Nacional Cayetano Heredia
Lima, ,
Peru
CHU De Bicetre
Paris, ,
France
Consultorio Royal Ctr
Panama, ,
Panama
SEMECO
San Jose, ,
Costa Rica
Additional Information:
Study ID Numbers: 302C; AI424-034
Study Start Date: February 2001
Record last reviewed: February 2004
Additional information available at: clinicaltrials.gov
Clinicaltrials.gov Reference link: NCT00013897
Other Hiv Infections Studies:
1. Endothelial Dysfunction as a Risk Factor in HIV Study
2. A Study to See Whether Two HIV Vaccines Are Safe and Can Prevent HIV Infection
3. Assessment of Attentional Functioning in Children with HIV-1 Infection
4. A Study of CI-1012 in HIV-Infected Patients
5. A Phase I Study of the Safety and Immunogenicity of rgp 120/HIV-1IIIB Vaccine in HIV-1 Seropositive Adult Volunteers
Related Studies:
Other HIV Infections Clinical Trials
Other New Jersey Clinical Trials
Other Somerville Clinical Trials
A Comparison of BMS-232632 with Efavirenz, Each in Combination with Zidovudine-Lamivudine
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