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A Comparative Trial of Valacyclovir Hydrochloride ( 256U87 ) and Acyclovir for the Suppression of Anogenital Herpes Infections in HIV-Infected Patients Clinical Trials Info presented on Clinical Trials Search is not intended to be a substitute for certified medical advice, visits or professional assistance using a real physician. We are not physicians. Always consult your dr. about A Comparative Trial of Valacyclovir Hydrochloride ( 256U87 ) and Acyclovir for the Suppression of Anogenital Herpes Infections in HIV-Infected Patients conditions. Clinical Trials Search.org is a site dedicated to listing clinical research studies in human subjects. A Comparative Trial of Valacyclovir Hydrochloride ( 256U87 ) and Acyclovir for the Suppression of Anogenital Herpes Infections in HIV-Infected Patients Clinical research trials and A Comparative Trial of Valacyclovir Hydrochloride ( 256U87 ) and Acyclovir for the Suppression of Anogenital Herpes Infections in HIV-Infected Patients health trials happen in many of localities throughout the U.S.. A clinical trial or clinical study is a research project with human volunteer subjects. Clinical drug trials and pharmaceutical clinical trials typically measure the effectualness of new drugs. The function of the studies / projects is to resolve particular human medical questions. Clinical trials are a popular manner for mDs, government agencies, and private sector corporations to discover remedies for all varieties of circumstances, like A Comparative Trial of Valacyclovir Hydrochloride ( 256U87 ) and Acyclovir for the Suppression of Anogenital Herpes Infections in HIV-Infected Patients. A Comparative Trial of Valacyclovir Hydrochloride ( 256U87 ) and Acyclovir for the Suppression of Anogenital Herpes Infections in HIV-Infected Patients Clinical Trials and other clinical trials allow volunteers to obtain healthcare treatment options before they are available to the masses. Some times the participants undergo professional assistance for free of charge, and occasionally they are paid for their time. Sometimes there is a cost for a A Comparative Trial of Valacyclovir Hydrochloride ( 256U87 ) and Acyclovir for the Suppression of Anogenital Herpes Infections in HIV-Infected Patients clinical trial. Human subjects often get the best healthcare available for their A Comparative Trial of Valacyclovir Hydrochloride ( 256U87 ) and Acyclovir for the Suppression of Anogenital Herpes Infections in HIV-Infected Patients condition. Dangers are a reality, however, and may include additional or frequent mD visits, healthcare dangers (potentially life-jeopardising), and/or the treatment being ineffectual. Trials are federally governed with rigorous guidelines to protect clinical trials patients.

Home > "A" Clinical Trials Conditions > A Comparative Trial of Valacyclovir Hydrochloride ( 256U87 ) and Acyclovir for the Suppression of Anogenital Herpes Infections in HIV-Infected Patients

A Comparative Trial of Valacyclovir Hydrochloride ( 256U87 ) and Acyclovir for the Suppression of Anogenital Herpes Infections in HIV-Infected Patients



A Comparative Trial of Valacyclovir Hydrochloride ( 256U87 ) and Acyclovir for the Suppression of Anogenital Herpes Infections in HIV-Infected Patients

For Condition: Herpes Simplex,HIV Infections
Status: Completed
Sponsor(s): Glaxo Wellcome ,
Synopsis: To determine the safety and efficacy of oral valacyclovir hydrochloride ( 256U87 ) compared to acyclovir in the treatment of recurrent anogenital herpes in HIV-infected patients with CD4 counts = or > 100 cells/mm3.
Details:
Eligibility:
Study Type:
  Interventional, Treatment, Safety Study
Minimum Age/Maximum Age: 18 Years/
Genders: Both
Protocol Entry Criteria: Inclusion Criteria Patients must have: - HIV infection with CD4 counts = or > 100 cells/mm3. - Documented culture of anogenital herpes simplex virus (HSV) within the last 5 years. - History of recurrent anogenital HSV infection, with a recurrence (with or without culture) within 1 year prior to study. Exclusion Criteria Co-existing Condition: Patients with the following symptoms and conditions are excluded: - Malabsorption or vomiting that would potentially limit the retention and absorption of oral therapy. Concurrent Medication: Excluded: - Systemic antiherpes medication. - Interferon. Patients with the following prior conditions are excluded: History of hypersensitivity to acyclovir.
Total Enrollment: 

Location and Contact Information:

George Washington Univ Med Ctr
Washington D.C.,  District of Columbia,  20037
United States
 

AIDS Research Consortium of Atlanta
Atlanta,  Georgia,  30308
United States
 

San Diego Naval Hosp
San Diego,  California,  921345000
United States
 

Northwestern Memorial Hosp
Chicago,  Illinois,  60611
United States
 

Regional Med Ctr at Memphis
Memphis,  Tennessee,  38103
United States
 

Infectious Disease Med Group / Adult Immunology Clinic
Oakland,  California,  94609
United States
 

Baylor College of Medicine / Texas Med Ctr
Houston,  Texas,  77030
United States
 

Univ of Arizona / Health Science Ctr
Tucson,  Arizona,  85724
United States
 

Dr Marcus Conant
San Francisco,  California,  94115
United States
 

Combat Group
Los Angeles,  California,  90028
United States
 

UCSD Med Ctr
San Diego,  California,  92103
United States
 

Buckley Braffman Stern Med Associates
Philadelphia,  Pennsylvania,  19107
United States
 

Baylor College of Medicine
Houston,  Texas,  77030
United States
 

Univ TX Med Branch / Ctr for Clinical Studies
Nassau Bay,  Texas,  77058
United States
 

Univ of Kansas School of Medicine
Wichita,  Kansas,  67214
United States
 

Univ of Pittsburgh / Graduate School of Public Health
Pittsburgh,  Pennsylvania,  15261
United States
 

Saint Vincent's Hosp and Med Ctr
New York City,  New York,  10011
United States
 

Rush Presbyterian - Saint Luke's Med Ctr
Chicago,  Illinois,  60612
United States
 

Mount Sinai Med Ctr
New York City,  New York,  10029
United States
 

Univ of Missouri at Kansas City School of Medicine
Kansas City,  Missouri,  64108
United States
 

Emory Univ School of Medicine
Atlanta,  Georgia,  30303
United States
 

West Haven Veterans Administration Med Ctr
West Haven,  Connecticut,  06516
United States
 

Whitman - Walker Clinic
Washington D.C.,  District of Columbia,  20009
United States
 

MacGregor Med Association
Houston,  Texas,  77054
United States
 

Infectious Diseases Research Clinic / Indiana Univ Hosp
Indianapolis,  Indiana,  46202
United States
 

Univ of Mississippi Med Ctr
Jackson,  Mississippi,  39216
United States
 

Georgetown Univ Med Ctr
Washington D.C.,  District of Columbia,  20007
United States
 

Beth Israel Med Ctr
New York City,  New York,  10003
United States
 

UCSF - San Francisco Gen Hosp
San Francisco,  California,  94110
United States
 

Univ of Rochester Med Ctr
Rochester,  New York,  14642
United States
 

St Paul Ramsey Med Ctr
St. Paul,  Minnesota,  55101
United States
 

Univ of South Florida
St. Petersburg,  Florida,  33705
United States
 

Univ TX Galveston Med Branch
Galveston,  Texas,  77550
United States
 

Univ of Iowa Hosp & Clinic
Iowa City,  Iowa,  52242
United States
 

UCI Med Ctr
Orange,  California,  92668
United States
 

Thomas Audetta Clinic
Houston,  Texas,  77006
United States
 

Univ of South Alabama
Mobile,  Alabama,  36604
United States
 

Veterans Administration Med Ctr / Regional AIDS Program
Washington D.C.,  District of Columbia,  20422
United States
 

Med College of Virginia
Richmond,  Virginia,  232980049
United States
 

Roger Williams Med Ctr
Providence,  Rhode Island,  02908
United States
 

St Louis Univ
St. Louis,  Missouri,  63104
United States
 

Univ of Maryland at Baltimore
Baltimore,  Maryland,  21201
United States
 

Los Angeles County - USC Med Ctr
Los Angeles,  California,  90033
United States
 

Dallas Associated Dermatologists
Dallas,  Texas,  75246
United States
 

ViRx Inc
San Francisco,  California,  94103
United States
 

Portland Veterans Adm Med Ctr / Rsch & Education Grp
Portland,  Oregon,  97210
United States
 


Additional Information:
Study ID Numbers:
  104B;  07
Study Start Date: 
Record last reviewed: April 1996
Additional information available at: clinicaltrials.gov
Clinicaltrials.gov Reference link: NCT00002084

Other Herpes Simplex Studies:
1. SP-303T Applied to the Skin of Patients with Herpes Simplex Virus (HSV) Infection and AIDS Who Have Not Had Success with Acyclovir

2. The Safety and Effectiveness of Valacyclovir HCl in the Treatment of Herpes Simplex or Varicella/Zoster Infections in HIV-1 Infected Children

3. A Phase I/II Study of the Safety and Efficacy of Topical 1-(S)-(3-Hydroxy-2-phosphonylmethoxypropyl)cytosine Dihydrate (Cidofovir; HPMPC) in the Treatment of Refractory Mucocutaneous Herpes Simplex Disease in Patients With AIDS

4. Phase III Randomized Study of Oral Acyclovir in Infants With Herpes Simplex Virus Infection Involving the Central Nervous System

5. Comparison of Foscarnet Versus Vidarabine in the Treatment of Herpes Infection in Patients with AIDS Who Have Not Had Success with Acyclovir

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A Comparative Trial of Valacyclovir Hydrochloride ( 256U87 ) and Acyclovir for the Suppression of Anogenital Herpes Infections in HIV-Infected Patients

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