Search Clinical Trials
By Condition
By Location (USA)
By Location (Other)
By Sponsor
Resources
Privacy Policy
About Us
Disclaimer
4-PBA: Will it increase the level of Alpha 1-Antitrypsin(AAT) in persons with AAT deficiency? Clinical Trials Information presented on Clinical Trials Search is not intended to be a substitute for qualified health advice, trips or treatment by using a genuine doctor. We aren't doctors. Always consult your mD on 4-PBA: Will it increase the level of Alpha 1-Antitrypsin(AAT) in persons with AAT deficiency? conditions. Clinical Trials Search.org is a site committed to listing clinical research studies in human subjects. 4-PBA: Will it increase the level of Alpha 1-Antitrypsin(AAT) in persons with AAT deficiency? Clinical research trials and 4-PBA: Will it increase the level of Alpha 1-Antitrypsin(AAT) in persons with AAT deficiency? health trials take place in a lot of of cities across the US. A clinical trial or clinical study is a research project with human volunteer subjects. Clinical drug trials and pharmaceutical clinical trials generally measure the potency of new drugs. The aim of the studies / projects is to answer specific human medical questions. Clinical trials are a popular manner for physicians, government agencies, and private sector corporations to discover remedies for all kinds of circumstances, like 4-PBA: Will it increase the level of Alpha 1-Antitrypsin(AAT) in persons with AAT deficiency?. 4-PBA: Will it increase the level of Alpha 1-Antitrypsin(AAT) in persons with AAT deficiency? Clinical Trials and other clinical trials allow for volunteers to have health treatment alternatives before they are available to the general public. Many times the test subjects obtain treatment for without cost, and occasionally they are paid for their time. Sometimes there is a cost for a 4-PBA: Will it increase the level of Alpha 1-Antitrypsin(AAT) in persons with AAT deficiency? clinical trial. Subjects oftentimes recieve the most effective healthcare possible for their 4-PBA: Will it increase the level of Alpha 1-Antitrypsin(AAT) in persons with AAT deficiency? condition. Hazards are a reality, however, and could include additional or frequent doctor visits, healthcare dangers (perhaps life-threatening), and/or the treatment being ineffective. Trials are federally governed with exacting guidelines to protect clinical trials subjects.

Home > "4" Clinical Trials Conditions > 4-PBA: Will it increase the level of Alpha 1-Antitrypsin(AAT) in persons with AAT deficiency?

4-PBA: Will it increase the level of Alpha 1-Antitrypsin(AAT) in persons with AAT deficiency?



4-PBA: Will it increase the level of Alpha 1-Antitrypsin(AAT) in persons with AAT deficiency?

For Condition: alpha 1-Antitrypsin Deficiency
Status: Recruiting
Sponsor(s): Alpha-1 Foundation ,
Synopsis: The purpose of this study is to find out whether 4-PBA will increase the level of AAT in persons with AAT deficiency whether or not they have liver disease.
Details:
Eligibility:
Study Type:
  Interventional, Treatment, Non-Randomized, Open Label, Active Control, Single Group Assignment, Safety/Efficacy Study
Minimum Age/Maximum Age: 18 Years/65 Years
Genders: Both
Protocol Entry Criteria: Inclusion Criteria: - Age 18-65 - Serum A1-PI levels <11uM an appropriate genetic phenotype/genotype - 5 of 10 subjects must have documented laboratory evidence of liver disease - Willingness to withold Prolastin therapy for 6 weeks prior to screening and throughout the 4-PBA dosing period (up to 3 months) Exclusion Criteria: - Any cause of liver disease other than Alpha-1 Antitrypsin deficiency - Evidence of advanced liver disease - HIV positive - Use of systemic steroids, ursodeoxycholic acid (Actigall, Urso), or herbs in the prior 6 months
Total Enrollment: 

Location and Contact Information:

Overall Study Official:
MarkBrantly,  Principal Investigator,  University of Florida

University of Florida Health Science Center *Recruiting*
Gainesville,  Florida,  32610-0225
United States
Recruiting  


Additional Information:
Study ID Numbers:
  87-2001; 
Study Start Date: November 2001
Record last reviewed: August 2003
Additional information available at: clinicaltrials.gov
Clinicaltrials.gov Reference link: NCT00067756

Other Alpha 1-Antitrypsin Deficiency Studies:
1. 4-PBA: Will it increase the level of Alpha 1-Antitrypsin(AAT) in persons with AAT deficiency?

2. Study of Genotype and Phenotype in Patients With Alpha 1-Antitrypsin Deficiency

3. Characterization of the Pathobiology of Early Lung Destruction in Alpha 1-Antitrypsin Deficient Individuals

Related Studies:

Other alpha 1-Antitrypsin Deficiency Clinical Trials
Other Florida Clinical Trials
Other Gainesville Clinical Trials

4-PBA: Will it increase the level of Alpha 1-Antitrypsin(AAT) in persons with AAT deficiency?

Modify your Search

  Other alpha 1-Antitrypsin Deficiency Clinical Trials
  Other Florida Clinical Trials
  Other Gainesville Clinical Trials


Warning: include(/var/www/cgi-bin/traxis/counter.php) [function.include]: failed to open stream: No such file or directory in /home/cts/domains/clinicaltrialssearch.org/public_html/index.php on line 103

Warning: include() [function.include]: Failed opening '/var/www/cgi-bin/traxis/counter.php' for inclusion (include_path='.:/usr/local/lib/php') in /home/cts/domains/clinicaltrialssearch.org/public_html/index.php on line 103